王鵬

王鵬，中國科學院上海高等研究院研究員。畢業於北京大學生命科學學院

系統生物學，基於網絡動態的重大疾病機理研究及生物標記物研發。

承擔科研項目情況：

“百人計劃”2013-2015

國家自然科學基金委面上項目， 2013-2016年，80萬

上海市科學技術委員會重點專項，2013-2015， 310萬

1. Chang H, Liu Y, Xue M, Liu H, Du S, Zhang L, et al. Synergistic action of master transcription factors controls epithelial-to-mesenchymal transition. Nucleic acids research 2016, 44(6): 2514-2527.

2. Li L, Wang D, Xue M, Mi X, Liang Y, Wang P. 3'UTR shortening identifies high-risk cancers with targeted dysregulation of the ceRNA network. Scientific reports 2014, 4: 5406.

3. Wang L, Hu X, Wang P, Shao ZM. The 3'UTR signature defines a highly metastatic subgroup of triple-negative breast cancer. Oncotarget 2016.

4. Mucida D, Husain MM, Muroi S, van Wijk F, Shinnakasu R, Naoe Y, Reis BS, Huang Y, Lambolez F, Docherty M, Attinger A, Shui JW, Kim G, Lena CJ, Sakaguchi S, Miyamoto C, Wang P, Atarashi K, Park Y, Nakayama T, Honda K, Ellmeier W, Kronenberg M, Taniuchi I, Cheroutre H: Transcriptional reprogramming of mature CD4? helper T cells generates distinct MHC class II-restricted cytotoxic T lymphocytes. Nat Immunol. 2013 143:281-9.

5. Chen C, Dow C, Wang P, Sidney J, Read A, Harmsen AG, Samuel JE, Peters B: Identification of CD4+ T cell epitopes in C. burnetii antigens targeted by antibody responses. 2011. PLoS One, 2011 Mar15;63:e17712

6. Wang P, Sidney J, Sette A, Peters B: Peptide binding predictions for all HLA class II loci. 2010. (BMC Bioinformatics. 2010; 11: 568)

7. Zhang H, Wang P, Papangelopoulos N, Xu Y, Sette A, Bourne PE, Lund O, Ponomarenko J, Nielsen M, Peters B: Limitations of ab initio predictions of peptide binding to MHC class II molecules. PLoS One. 2010, 5(2):e9272. (co-first author)

8. Wang P, Sidney J, Dow C, Mothe B, Sette A, Peters B: A systematic assessment of MHC class II peptide binding predictions and evaluation of a consensus approach. PLoS Comput Biol 2008, 4(4):e1000048.

9. Wang P, Yan B, Guo JT, Hicks C, Xu Y: Structural genomics analysis of alternative splicing and application to isoform structure modeling. Proc Natl Acad Sci U S A 2005, 102(52):18920-18925. ^[1]