-
李豔華
(東北農業大學動物藥學系主任)
鎖定
李豔華,東北農業大學動物醫學學院,教授,博士生導師,動物藥學系主任
[1]
。現為國家生豬產業技術體系崗位科學家
[2]
、中國畜牧獸醫學會獸醫藥理與毒理學分會常務理事、黑龍江省畜牧獸醫學會常務理事、黑龍江省畜牧獸醫雜誌編委、中獸藥產業技術創新戰略聯盟理事、獸用化學藥品技術創新戰略聯盟理事、河南省洛陽惠中獸藥有限公司專家顧問團成員
[3]
。
- 中文名
- 李豔華 [1]
- 出生日期
- 1970年10月 [1]
- 畢業院校
- 東北農業大學 [1]
李豔華科研項目
1.“十二五”國家科技支撐項目 抗豬鏈球菌病複方製劑的研製 ,50萬,主持
[4]
7.黑龍江省教育廳科學技術研究項目 大環內酯類藥物對豬鏈球菌體外生物被膜的作用及毒力因子影響,2萬,主持
[4]
李豔華省部級以上獎勵
4.禽流感H5和H9亞型滅活疫苗研製與應用 全國農牧漁業豐收獎 二等獎
[7]
李豔華近五年發表文章
[1] Ding W Y; Zhou Y H; Qu Q W; Cui W Q; God'spower B O; Liu Y Y; Li Y H*. Azithromycin Inhibits Biofilm Formation by Staphylococcus xylosus and Affects Histidine Biosynthesis Pathway[J]. Frontiers in Pharmacology, 2018
[8]
.
[2] Liu Y Y; Chen X R; Gao L F; Chen M; Cui W Q; Ding W Y; Chen X Y; God'spower B O; Li Y H*. Spectrum-effect Relationships between the Bioactive Ingredient of Syringa oblata Lindl. Leaves and its Role in Inhibiting the Biofilm Formation of Streptococcus suis[J]. Frontiers in Pharmacology, 2018
[9]
.
[3] Ding W Y;Sun J;Lian H;Xu C G;Liu X;Zheng S D;Zhang D;Han X P;Liu Y Y;Chen X Y,God'spower B O; Li Y H *. The Influence of Shuttle-Shape Emodin Nanoparticles on the Streptococcus suiBiofilm[J].Frontiers in Pharmacology,2018
[10]
[4] Zhou Y H;Xu C G;Yang Y B;Xing X X;Liu X;Qu Q W;Ding W Y;Bello-Onaghise G; Li Y H *. Histidine Metabolism and IGPD Play a Key Role in Cefquinome Inhibiting Biofilm Formation of Staphylococcus xylosus.[J]. Frontiers in Pharmacology, 2018, 9:665
[11]
.
[5] Li Y H;Zhou Y H;Ren Y Z;Xu C G;Liu X;Liu B;Chen J Q;Ding W Y;Zhao Y L;Yang Y B;Wang S;Liu D. Inhibition of Streptococcus suis Adhesion and Biofilm Formationin Vitroby Water Extracts of Rhizoma Coptidis[J]. Frontiers in Pharmacology, 2018, 9
[12]
.
[6] Liu Y Y;Wang T Z;Ding W Y;Dong C L;Wang X T;Chen J Q; Li Y H *. Dissolution and oral bioavailability enhancement of praziquantel by solid dispersions.[J]. Drug Deliv Transl Res, 2018(2):1-11
[13]
.
[7] Bai, J W;Yang Y B;Wang S;Gao L F;Chen J Q;Ren Y Z;Ding W Y;Muhammad I; Li Y H *. Syringa oblata Lindl. Aqueous Extract Is a Potential Biofilm Inhibitor in S. suis[J]. Frontiers in Pharmacology, 2017, 8(e89059):26
[14]
.
[8] Wang S;Wang C;Gao L F;Cai H;Zhou Y H;Yang Y B;Xu C G; Ding W Y; Chen J Q;Muhammad I; Li Y H *. Rutin Inhibits Streptococcus suis Biofilm Formation by Affecting CPS Biosynthesis[J]. Frontiers in Pharmacology, 2017, 8:379
[15]
[9] Ding W Y;Li Y H;Lian H;Ai X Y;Zhao Y L;Yang Y B;Han Q;Liu X;Chen X Y;He Z G; Li Y H *. Sub-Minimum Inhibitory Concentrations of Rhubarb Water Extracts Inhibit Streptococcus suis Biofilm Formation[J]. Frontiers in Pharmacology, 2017, 8:379
[16]
[10] Xu C G;Yang Y B;Zhou Y H;Hao M Q;Ren Y Z;Wang X T;Chen J Q;Muhammad I;Wang S;Liu D; Li Y H *. Comparative Proteomic Analysis Provides insight into the Key Proteins as Possible Targets Involved in Aspirin Inhibiting Biofilm Formation of Staphylococcus xylosus.[J]. Frontiers in Pharmacology, 2017, 8:543
[17]
[11] Liu X;Zheng S D;Qin Y;Ding W Y;Tu Y B;Chen, X R;Wu Y Z;Li Y H;Cai X H. Experimental Evaluation of the Transport Mechanisms of PoIFN-α in Caco-2 Cells[J]. Frontiers in Pharmacology, 2017, 8:781
[18]
[12] Chen X R;Wang X T;Hao M Q;Zhou Y H;Cui W Q;Xing X X;Xu C G;Bai J W;Li Y H*. Homology Modeling and Virtual Screening to Discover Potent Inhibitors Targeting the Imidazole Glycerophosphate Dehydratase Protein in Staphylococcus xylosus.[J]. Frontiers in chemistry, 2017, 5:9
[19]
[13] S. Wang, Y.B. Yang, Y.L. Zhao, H.H. Zhao, J.W. Bai, J.Q. Chen, Y.H. Zhou, C. Wang, and Y.H. Li*, Sub-MIC Tylosin Inhibits Streptococcus suis Biofilm Formation and Results in Differential Protein Expression, Frontiers in Microbiology,Vol (7),No. 26, 1-9, 2016
[20]
[14] Y.B. Yang, J.Q. Chen, Y.L. Zhao, J.W. Bai, W.Y. Ding, Y.H. Zhou, X.Y. Chen, D. Liu, and Y.H. Li*, Sub-MICs of Azithromycin Decrease Biofilm Formation of Streptococcus suis and Increase Capsular Polysaccharide Content of S. suis, Frontiers in Microbiology, Vol(7), No. 1-8, 2016
[21]
[15] Y.B. Yang, S. Wang, C. Wang, Q.Y. Huang, J.W. Bai, J.Q. Chen, X.Y. Chen, and Y.H. Li*, Emodin affects biofilm formation and expression of virulence factors in Streptococcus suis ATCC700794, Archives of Microbiology,Vol (197), No. 10, 1173-1180,2015
[4]
[22]
[16] Y.L. Zhao, Y.H. Zhou, J.Q. Chen, Q.Y. Huang, Q. Han, B. Liu, G.D. Cheng, and Y.H. Li*, Quantitative proteomic analysis of sub-MIC erythromycin inhibiting biofilm formation ofS-suis in vitro, Journal of Proteomics,Vol (116), No.1-14,2014
[4]
[23]
[17] P.F. Wan, Z.L. Sheng, Q. Han, Y.L. Zhao, G.D. Cheng, and Y.H. Li*, Enrichment and purification of total flavonoids from Flos Populi extracts with macroporous resins and evaluation of antioxidant activities in vitro, Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences,Vol (945),No.68-74,2014
[4]
[24]
[18] G.D. Cheng, Y.L. Zhao, H. Li, Y. Wu, X.X. Li, Q. Han, C.S. Dai, and Y.H. Li*, Forsythiaside attenuates lipopolysaccharide-induced inflammatory responses in the bursa of Fabricius of chickens by downregulating the NF-kappa B signaling pathway, Experimental and Therapeutic Medicine, Vol(7), No.1,179-184, 2014
[25]
[19] Z. Sheng, Y. Wang, P. Wan, and Y.H. Li*, ULTRASOUND-ASSISTED EXTRACTION OF TOTAL FLAVONOIDS FROM LEAVES OF SYRINGA OBLATA LINDL, Latin American Applied Research, Vol(44),No.2, 131-131, 2014
[26]
[20] X. Gao, G. Xu, Y. Liu, J.Q. Chen, Y. Cui, G.D. Cheng, Q.B. Yan, and Y.H. Li*, Validation of a UPLC/MS/MS Method for Determination of Compound Amoxicillin and Tylosin in Swine Plasma and its Application in a Pharmacokinetic Study, Journal of Pure and Applied Microbiology,Vol (7), No. 655-662,2013
[27]
[21] Z.L. Sheng, P.F. Wan, C.L. Dong, and Y.H. Li*, Optimization of total flavonoids content extracted from Flos Populi using response surface methodology, Industrial Crops and Products,Vol (43), No.778-786,2013
[28]
[27] 高凌飛#,陳儉清,盛尊來,劉霄磊,魏樹閣,張叢祿,房良,李豔華*. 丁香葉干預豬鏈球菌體外生物被膜形成有效部位的篩選[J]. 黑龍江畜牧獸醫,2015,(13):189-191
[34]
.
[33] 程廣東#,嶽麗紅,呂冬雲,盛尊來,李盛舉,張強,王偉娥,張偉,趙玉林,李豔華*. 連翹酯苷A抗LPS介導大鼠類風濕性關節炎機制研究[J]. 東北農業大學學報,2014,(06):103-108.
[40]
[35] 李豔華*,李賢賢,陳儉清,王宇希,趙玉蓮,吳悦,李鶴,程廣東. 丁香葉醇提物對豬流感病毒感染BALB/C小鼠血清中細胞因子的影響[J]. 東北農業大學學報,2013,(12):6-9.
[42]
李豔華所獲專利情況
[2]預防或治療豬鏈球菌病的複方抗生素組合物 發明專利 CN200910137645.9
[49]
[3]丁香葉或其提取物在製備抗豬流感病毒藥物中的用途 發明專利 CN201210186698.1
[49]
[5]水楊酸在製備抑制木糖葡萄球菌生物被膜藥物中的用途 發明專利 CN201510357710.4
[50]
[7]阿司匹林在製備抑制木糖葡萄球菌生物被膜藥物中的用途 發明專利 CN201510357706.8
[52]
- 參考資料
-
- 1. 李豔華簡介 .東北農業大學動物醫學學院[引用日期2018-10-04]
- 2. 關於公示現代農業產業技術體系“十三五”新增崗位科學家候選人名單的通知 .中華人民共和國農業部[引用日期2018-10-06]
- 3. 學校“巾幗女傑”獲得者——李豔華 .東北農業大學校工會[引用日期2018-10-06]
- 4. 博士生導師詳細簡介 .博士生導師詳細簡介[引用日期2018-10-06]
- 5. 哈爾濱市科學技術協會 .哈爾濱市科學技術協會.2014[引用日期2018-10-06]
- 6. 博士生導師簡介 .東北農業大學[引用日期2018-10-06]
- 7. 中國農業科學院 .中國農業科學院官網[引用日期2018-10-06]
- 8. Azithromycin Inhibits Biofilm Formation by Staphylococcus xylosus and Affects Histidine Biosynthesis Pathway .Frontiers in Pharmacology[引用日期2018-10-06]
- 9. Spectrum-effect Relationships between the Bioactive Ingredient of Syringa oblata Lindl. Leaves and its Role in Inhibiting the Biofilm Formation of Streptococcus suis .Frontiers in Pharmacology[引用日期2018-10-06]
- 10. The Influence of Shuttle-Shape Emodin Nanoparticles on the Streptococcus suis Biofilm .Frontiers in Pharmacology[引用日期2018-10-06]
- 11. Histidine Metabolism and IGPD Play a Key Role in Cefquinome Inhibiting Biofilm Formation ofStaphylococcus xylosus .Frontiers in Pharmacology[引用日期2018-10-06]
- 12. Inhibition of Streptococcus suis Adhesion and Biofilm Formationin Vitroby Water Extracts of Rhizoma Coptidis .Frontiers in Pharmacology[引用日期2018-10-06]
- 13. Dissolution and oral bioavailability enhancement of praziquantel by solid dispersions .Drug Delivery Translational Research[引用日期2018-10-06]
- 14. Syringa oblata Lindl. Aqueous Extract Is a Potential Biofilm Inhibitor in S. suis .Frontiers in Pharmacology[引用日期2018-10-06]
- 15. Rutin Inhibits Streptococcus suis Biofilm Formation by Affecting CPS Biosynthesis . Frontiers in Pharmacology[引用日期2018-10-06]
- 16. Sub-Minimum Inhibitory Concentrations of Rhubarb Water Extracts Inhibit Streptococcus suis Biofilm Formation .Frontiers in Pharmacology[引用日期2018-10-06]
- 17. Comparative Proteomic Analysis Provides insight into the Key Proteins as Possible Targets Involved in Aspirin Inhibiting Biofilm Formation of Staphylococcus xylosus .Frontiers in Pharmacology[引用日期2018-10-06]
- 18. Experimental Evaluation of the Transport Mechanisms of PoIFN-α in Caco-2 Cells .Frontiers in Pharmacology[引用日期2018-10-06]
- 19. Homology Modeling and Virtual Screening to Discover Potent Inhibitors Targeting the Imidazole Glycerophosphate Dehydratase Protein in Staphylococcus xylosus .Frontiers in chemistry[引用日期2018-10-06]
- 20. Sub-MIC Tylosin Inhibits Streptococcus suis Biofilm Formation and Results in Differential Protein Expression .Frontiers in Microbiology[引用日期2018-10-06]
- 21. Sub-MICs of Azithromycin Decrease Biofilm Formation of Streptococcus suis and Increase Capsular Polysaccharide Content of S. suis .Frontiers in Microbiology[引用日期2018-10-06]
- 22. Emodin affects biofilm formation and expression of virulence factors in Streptococcus suis ATCC700794 .Archives of Microbiology[引用日期2018-10-06]
- 23. Quantitative proteomic analysis of sub-MIC erythromycin inhibiting biofilm formation of S-suis in vitro . Journal of Proteomics[引用日期2018-10-06]
- 24. Enrichment and purification of total flavonoids from Flos Populi extracts with macroporous resins and evaluation of antioxidant activities in vitro . Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences[引用日期2018-10-06]
- 25. Forsythiaside attenuates lipopolysaccharide-induced inflammatory responses in the bursa of Fabricius of chickens by downregulating the NF-kappa B signaling pathway . Experimental and Therapeutic Medicine[引用日期2018-10-06]
- 26. ULTRASOUND-ASSISTED EXTRACTION OF TOTAL FLAVONOIDS FROM LEAVES OF SYRINGA OBLATA LINDL .Latin American Applied Research[引用日期2018-10-06]
- 27. Validation of a UPLC/MS/MS Method for Determination of Compound Amoxicillin and Tylosin in Swine Plasma and its Application in a Pharmacokinetic Study .Journal of Pure and Applied Microbiology[引用日期2018-10-06]
- 28. Optimization of total flavonoids content extracted from Flos Populi using response surface methodology .Industrial Crops and Products[引用日期2018-10-06]
- 29. 車前草水提物抗腹瀉作用的研究 .中國知網[引用日期2018-10-09]
- 30. 阿司匹林對木糖葡萄球菌體外生物被膜的作用 .中國知網[引用日期2018-10-09]
- 31. 烏梅肉提取物抗腹瀉作用研究 .中國知網[引用日期2018-10-09]
- 32. 響應面法優化丁香葉總皂苷提取工藝 .中國知網[引用日期2018-10-09]
- 33. 大環內酯類藥物對木糖葡萄球菌生物被膜形成的影響 .中國知網[引用日期2018-10-09]
- 34. 丁香葉干預豬鏈球菌體外生物被膜形成有效部位的篩選 .中國知網[引用日期2018-10-09]
- 35. 黃連水提物鹽酸小檗鹼及黃連鹼對豬鏈球菌生物被膜的體外干預作用 .中國知網[引用日期2018-10-09]
- 36. 豬鏈球菌的分型鑑定及其體外形成生物被膜的研究 .中國知網[引用日期2018-10-09]
- 37. 響應面法優化丁香葉總酚酸提取工藝 .中國知網[引用日期2018-10-09]
- 38. 丁香葉水提物對豬鏈球菌體外生物被膜的作用 .中國知網[引用日期2018-10-09]
- 39. 阿苯達唑固體分散體的製備及分析 .中國知網[引用日期2018-10-09]
- 40. 連翹酯苷A抗LPS介導大鼠類風濕性關節炎機制研究 .中國知網[引用日期2018-10-09]
- 41. 吡喹酮聯合載體固體分散體的製備及其性質考察 .中國知網[引用日期2018-10-09]
- 42. 丁香葉醇提物對豬流感病毒感染BALB/C小鼠血清中細胞因子的影響 .中國知網[引用日期2018-10-09]
- 43. 連翹酯苷對脂多糖誘導的肉雞肝臟抗氧化作用的影響 .中國知網[引用日期2018-10-09]
- 44. 木樨科丁香葉中總黃酮的最佳提取工藝研究 .中國知網[引用日期2018-10-09]
- 45. 連翹酯苷對脂多糖誘導的雞胸腺組織抗氧化功能的影響 .中國知網[引用日期2018-10-09]
- 46. 連翹酯苷對LPS誘導的肉雞法氏囊中NO及抗氧化酶活性的影響 .中國知網[引用日期2018-10-09]
- 47. 連翹顆粒劑的急性亞急性毒性試驗研究 .中國知網[引用日期2018-10-09]
- 48. 豬鏈球菌菌株及其用途 .中國專利數據庫知網版[引用日期2018-10-09]
- 49. 博士生導師--李豔華教授 .東北農業大學研究生院[引用日期2018-10-05]
- 50. 水楊酸在製備抑制木糖葡萄球菌生物被膜藥物中的用途 .中國專利數據庫知網版[引用日期2018-10-09]
- 51. 大黃酸在製備抑制木糖葡萄球菌生物被膜藥物中的用途 .中國專利數據庫知網版[引用日期2018-10-09]
- 52. 阿司匹林在製備抑制木糖葡萄球菌生物被膜藥物中的用途 .中國專利數據庫知網版[引用日期2018-10-09]
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