王愛華

1989年6月本科畢業於西北農業大學獸醫系5年制獸醫專業，獲農學學士學位；2008年6月博士畢業於西北農林科技大學動物醫學院臨牀獸醫學專業，獲農學博士學位。1989年7月至1992年6 月在天津市農工商總公司東海公司現代化養雞廠從事獸醫工作，助理獸醫師兼獸醫室主任；1992年7月至今於西北農林科技大學動物醫學院預防獸醫學系從事教學與科研工作，先後晉升為講師、副教授、教授；2006年7月至2006年12月於加拿大圭爾夫大學細胞與分子生物學系研修。 ^[1] 

分子病原學與免疫學、動物疫病防制。

主要研究內容：病原微生物致病機制、病原與宿主互作、檢測製劑及新型疫苗。 ^[1] 

畜牧微生物學、動物微生物與免疫學、獸醫微生物學 ^[1] 

[1]Wang X, Lin P, Li Y, Xiang C, Yin Y, Chen Z, Du Y, Zhou D, Jin Y, and Wang A*. Brucella suis Vaccine Strain 2 Induces Endoplasmic Reticulum Stress that Affects Intracellular Replication in Goat Trophoblast Cells In vitro.Front Cell Infect Microbiol. 2016, 6: 19. doi: 10.3389/fcimb.2016.00019.

[2]Chen F, Wang N, Yang D, Wen X, Mahmoud T N, Zhou D, Tang K, Lin P, Wang A*, and Jin Y.. Herp depletion arrests the S phase of the cell cycle and increases estradiol synthesis in mouse granulosa cells.J Reprod Dev. 2016 Jan 15. [Epub ahead of print]

[3]Chen F, Lin P, Wang N, Yang D, Wen X, Zhou D, Wang A*, and Jin Y. Herp depletion inhibits zearalenone-induced cell death in RAW 264.7 macrophages. Toxicol In Vitro. 2016, 32: 115-122

[4]Zhou J, Dai R, Lei L, Lin P, Lu X, Wang X, Tang K, Wang A, and Jin Y. Establishment and evaluation of a stable steroidogenic goat Leydig cell line. Anim Sci J. 2016, 87（4）：492-502

[5]Chen F L, Li Q, Zhang J Y, Lei L J, Zhang Z, Mahmoud T N, Wang X G, Lin P F, Jin Y P, and Wang A H*. Silencing effect of lentiviral vectors encod-ing shRNA of Herp on endoplasmic reticulum stress and inflammatory responses in RAW 264.7 macrophages.Genet Mol Res.2015, 14(4): 17587-91758

[6]Lin P, Chen F, Sun J, Zhou J, Wang X, Wang N, Li X, Zhang Z, Wang A*, and Jin Y. Mycotoxin zearalenone induces apoptosis in mouse Leydig cells via an endoplasmic reticulum stress-dependent signalling pathway.Reprod Toxicol. 2015, 52: 71-77

[7]Wang X, Lin P, Yin Y, Zhou J, Lei L, Zhou X, Jin Y, and Wang A. Brucella suis vaccine strain S2-infected immortalized caprine endometrial epithelial cell lines induce non-apoptotic ER-stress.Cell Stress Chaperones. 2015, 20(3): 399-409

[8]Chen F, Li Q, Zhang Z, Lin P, Lei L, Wang A*, and Jin Y. Endoplasmic Reticulum Stress Cooperates in Zearalenone-Induced Cell Death of RAW 264.7 Macrophages.Int J Mol Sci.2015, 16(8): 19780-19795

[9]Chen F, Lin P F, Li X, Sun J, Zhang Z, Du E, Wang A, and Jin Y P. Construction and expression of lentiviral vectors encoding recombinant mouse CREBZF in NIH 3T3 cells.Plasmid.2014, 76C: 24-31

[10]Lin P, Jin Y, Lan X, Yang Y, Chen F, Wang N, Li X, Sun Y, and Wang A*. GRP78 expression and regulation in the mouse uterus during embryo implantation. J Mol Histol.2014, 45(3): 259-268

[11]Lin P, Lan X, Chen F, Yang Y, Jin Y, Wang A*. Reference gene selection for real-time quantitative PCR analysis of the mouse uterus in the peri-implantation period. PLoS One. 2013, 8(4): e62462.

[12]Lin P, Chen F, Wang N, Wang X, Li X, Zhou J, Jin Y, Wang A*. CREBZF expression and hormonal regulation in the mouse uterus. Reproductive Biology and Endocrinology, 2013;11(1):110. doi:10.1371/journal.pone.0062462

[13]Lan X, Jin Y, Yang Y, Lin P, Hu L, Cui C, Li Q, Li X, Wang A*. Expression and localization of Luman RNA and protein during mouse implantation and decidualization. Theriogenology. 2013, 80(2):138-144.

[14]Yang Y, Jin Y, Martyn AC, Lin P, Song Y, Chen F, Hu L, Cui C, Li X, Li Q, Lu R, Wang A* . Expression pattern implicates a potential role for luman recruitment factor in the process of implantation in uteri and development of preimplantation embryos in mice. Journal Reproduction and Development. 2013, 59(3): 245-251.

[15]Yang Y, Jin Y, Lin P, Hu L, Cui C, Li X, Li Q, Wang A*.The expression and localization of LRF in the female reproductive tract of cycling mice throughout the estrous cycle. Journal of Immunoassay and Immunochemistry. 2013, 34(4): 313-322.

[16]Xuefeng Qi, Yanyan Qu, Zhichun Nan, Yaping Jin, Xianjun Zhao, Aihua Wang* Stromal-epithelial interactions modulate the effect of ovarian steroids on goat uterine epithelial cell interleukin-18 release. Domestic Animal Endocrinology, 2012, 42: 210-21.

[17]Lin PF, Chen FL, Yang YZ, Song YJ, Li X, Lan XL, Jin YP, Wang. AH*.GRP78 expression and immunohistochemical localization in the female reproductive tract of mice. Theriogenology, 2012, 78: 1824-1829.

[18]Xuefeng Qi, Yanyan Qu, Zhichun Nan, Yaping Jin, Xianjun Zhao, Aihua Wang*. Caprine endometrial stromal cells modulate the effects of steroid hormones on cytokine secretion by endometrial epithelial cells in vitro. Reproductive Biology, 2012, 12(3):309-315.

[19]Hu L，Cui C， Song Y，Wang X，Jin Y, Wang A*, Zhang Y. An alternative method for cDNA cloning from surrogate eukaryotic cells transfected with the corresponding genomic DNA. Biotechnology Letters, 2012, 34: 1251-1255.

[20]Yanyan Zhang, Aihua Wang*, Qingxia Wu, Hongxia Sheng, Yaping Jin. Establishment and characteristics of immortal goat endometrial epithelial cells and stromal cells with hTERT. Journal of animal and veterinary advances, 2010, 9(21): 2738-2747.

[21] Lei Yang, Xiangguo Wang, Lanjie lei, Guangdong Zhang, Qin Xu, Jianpo Zhang, Chunnan Zhang, Jiao Yu, Pengfei Lin, Yaping Jin, Aihua Wang*. Construction of eukaryotic expression vector of main B. Melitensis S19 outer membrane proteins. Journal of Pure and Applied Microbiology, 2014, 8(1),

[22]胡林勇, 陳華濤, 李倩, 徐曉彬, 王愛華, 靳亞平. 山羊β-乳球蛋白基因打靶載體的構建[J]. 中國農業科學, 2011, 44(11):2364-2370

[23]《畜牧微生物學實驗指導》王愛華編著.北京：中國農業出版社. ISBN 978-7-109-17194-72012.國家級動物科學實驗教學示範中心繫列資助教材

[24]國家發明專利：一種法氏囊素的提取方法及其在疾病治療和免疫中的應用，ZL200310105809. 第1發明人 ^[1] 

1. Luman在布魯氏菌調節非摺疊蛋白反應和細胞凋亡抑制中的作用及其機制研究，國家自然科學基金(31672584)，主持，直接經費58萬元，2017.01-2020.12

2. 奶山羊重大疫病防控關鍵技術研究與示範，陝西省科技廳(2016KTZDNY02-06)，直接經費15萬元，2017.01-2019.12

3.羊布魯菌病防控與預警關鍵技術研究，陝西省農業創新(2012NKC01-17)，主持，10萬元，2012-2014

4.畜禽疫病檢測診斷技術與疫苗研製，陝西省科技攻關(2009K01-19)，主持，3萬元，2009-2011

5.內質網應激在布魯氏菌感染調控中的作用及其機制，家畜疫病病原生物學國家重點實驗室(蘭州獸醫研究所)開放基金(SKLVEB2015KFKT-0017)，主持，5萬元，2015-2017

6.β-乳球蛋白基因敲除奶山羊新品種培育，農業部生物新品種培育重大專項(2014 ZX08008-004)，子課題，60萬，2014-2015

7.奶山羊新品種培育，農業部生物新品種培育重大專項(2011ZX08008-004)，子課題，55萬元，2011-2013

8.LRF介導的內質網應激在胚胎着牀過程中的作用及其調節機制，國家自然科學基金(31372499)，主要參加，80萬元，2014-2017 ^[1] 

2009年獲校級優秀青年教師指導教師 ^[1]