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張蕊

(中國農業大學動物醫學院副教授)

鎖定
張蕊,女,博士,中國農業大學動物醫學院副教授。
中文名
張蕊
出生日期
1983年5月
學位/學歷
博士
任職院校
中國農業大學

張蕊人物經歷

張蕊教育經歷

Ÿ 2003~2007 西南大學動物醫學專業本科, 獲獸醫學學士學位
Ÿ 2007~2010 中國農業大學預防獸醫學專業碩士研究生,獲獸醫學碩士學位
Ÿ 2010~2014 加拿大University of Saskatchewan獸醫微生物及腫瘤學專業博士研究生,獲哲學博士學位 [1] 

張蕊工作經歷

Ÿ 2015~至今 中國農業大學基礎獸醫系,副教授
Ÿ 主講課程:本科《獸醫生物技術》,研究生《細胞生物學實驗技術 [1] 

張蕊研究方向

Ÿ 豬偽狂犬病毒(PRV)等模式病毒抑制宿主天然免疫的分子機制研究
Ÿ 腫瘤發生和發展的信號轉導機制及調控途徑研究 [1] 

張蕊學術成果

張蕊在研項目

Ÿ 2016.01-2018.12,國家自然科學基金青年科學基金項目:凋亡相關蛋白BTF在豬偽狂犬病毒(PRV)裂解性感染中的抗病毒作用與機制(31500703),課題主持人
Ÿ 2016.01-2017.12,中央高校基本科研業務費青年教師創新項目:豬偽狂犬病毒(PRV)及其相關蛋白對早幼粒細胞血病蛋白核體(PML -NBs)的影響和分子機制研究(2016QC001),課題主持人
Ÿ 2017.01-2020.12,國家自然科學基金面上項目: DNA損傷應答相關蛋白Bclaf1在HIF1低氧應激系統中的作用(31671488),課題主要參與人 [1] 

張蕊發表論文

(1) Zhang, Rui,Thamm DH,Misra, Vikram,The effect of ZhangfeiCREBZF on cell growth, differentiation,apoptosis, migration, and the UPR in several canine osteosarcoma cell lines,BMC Vet Res,2015, 10.1186s12917-015-0(15-0331-y.).
(2) Zhang, Rui,Misra, Vikram,Effects of cyclic AMP response element binding protein-Zhangfei (CREBZF) on the unfolded protein response and cell growth are exerted through the tumor suppressor p53.,Cell Cycle,2014,13(2):279-292.
(3) Zhang, Rui,Rapin, Noreen,Ying, Zhengxin,Shklanka, Erika,Bodnarchuk, Timothy W,Verge, Valerie M K,Misra, Vikram,ZhangfeiCREB-ZF - a potential regulator of the unfolded protein response.,PLos One,2013,8(10):e77256-e77256.
(4) Zhang,Rui, Pu,Juan, Su,Jingliang, Zhao,Jixun, Wang,Xiaoting, Zhang,Shouping, Li, Xiaojiao, Zhang, Guozhong, Phylogenetic characterization of Newcastle disease virus isolated in the mainland of China during 2001-2009. Veterinary Microbiology,2010,141(3-4):246-257.
(5) Zhang, Rui,Wang, Xiaoting,Su, Jingliang,Zhao, Jixun,Zhang, Guozhong,Isolation and analysis of two naturally-occurring multi-recombination Newcastle disease viruses in China.,Virus Research,2010,151(1):45-53.
(6) Ying, Zhengxin,Zhang, Rui,Verge, Valerie M K,Misra, Vikram,Cloning and Characterization of Rat Luman/CREB3, A Transcription Factor Highly Expressed in Nervous System Tissue.,Journal of Molecular Neuroscience,2015,55(2):347-354.
(7) Zheng J, Lang Y, Zhang Q, Cui D, Sun H, Jiang J, Jiang L, Chen Z, Zhang R, Gao Y, Tian W, Wu W, Tang J, Chen Z. Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation. Gene & Development, 2015, 29(14):1524-34.
(8) Xu A, Qin C, Lang Y., Wang M, Lin M, Li C, Zhang R, Tang J,A simple and rapid approach to manipulate Pseudorabies virus genome by CRISPRCas9 system,Biotechnology Letters,2015,37(6):1265-72.
(9) Kong, Weili,Liu, Lirong,Wang, Yu,He, Qiming,Wu, Sizhe,Qin, Zhihua,Wang, Jinliang,Sun, Honglei,Sun, Yipeng,Zhang, Rui,Pu, Juan,Liu, Jinhua,C-terminal elongation of NS1 of H9N2 influenza virus induces a high level of inflammatory cytokines and increases transmission.,Journal of General Virology,2015,96(Pt 2):259-268.
(10) Bergeron, T,Zhang, R,Elliot, K,Rapin, N,MacDonald, V,Linn, K,Simko, E,Misra, V,The effect of Zhangfei on the unfolded protein response and growth of cells derived from canine and human osteosarcomas.,Vet Comp Oncol,2013,11(2):140-150.
(11) Zhang, G Z,Zhang, R,Zhao, H L,Wang, X T,Zhang, S P,Li, X J,Qin, C Z,Lv, C M,Zhao, J X,Zhou, J F,A safety assessment of a fowlpox-vectored Mycoplasma gallisepticum vaccine in chickens.,Poult Sci,2010,89(6):1301-1306. [1] 
參考資料
  • 1.    張蕊  .中國農業大學[引用日期2019-11-10]