鄧勇

2001年7月獲四川大學華西藥學院藥物化學專業博士學位後留校任教，從事藥物化學的教學和科研工作。 ^[1] 

先後主講本科生及研究生的《藥物合成反應》、《藥物化學》、《有機雜環化學》等課程。 ^[1] 

近年來，作為負責人或主研人員承擔國家“十二五”重大新藥創制項目2項、國家自然科學基金2項、國家“十一五”重大新藥創制項目2項、教育部博士點基金1項、國家“十五”重大科技專項“創新藥物與中藥現代化”項目1項、四川大學青年科學基金1項、企業藥物開發項目20餘項（包括：鹽酸沙丙蝶呤、雷美替胺、利奈唑胺、利伐沙班、熊去氧膽酸、牛磺熊去氧膽酸、奧貝膽酸、氟比洛芬、重酒石酸卡巴拉汀、地紅黴素、氯雷他啶、鹽酸替扎尼定、拉米夫定、曲氟尿苷、奧沙利鉑、他唑巴坦、格列美脲等）；發表研究論文60餘篇（SCI收錄40篇）；申請發明專利70餘件（國際申請5件），其中已授權50件；參編教材3本。被評為四川省學術和技術帶頭人後備人選、四川省衞生廳學術和技術帶頭人。 ^[1] 

國家科技獎勵評審專家，國家自然科學基金同行評審專家，廣東省、浙江省、四川省及成都市科技計劃項目評審專家，四川省新藥評審委員，Eur. J. Med. Chem.、Bioorg. Med. Chem.、Bioorg. Med. Chem. Lett.、Chin. Chem. Lett.等多本雜誌的審稿人。 ^[1] 

1、抗神經退行性疾病藥物研究

2、抗腫瘤藥物研究

3、藥物合成工藝及產業化研究 ^[1] 

1、Design, synthesis and evaluation of scutellarein-O-acetamidoalkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer’s disease. Eur. J. Med. Chem. 2017, 135, 307-323.

2、Pyridoxine-Resveratrol hybrids mannich base derivatives as novel dual inhibitors of AChE and MAO-B with antioxidant and metal-chelating properties for the treatment of Alzheimer’s disease. Bioorg. Chem. 2017, 71, 305-314.

3、Multifunctional thioxanthone derivatives with acetylcholinesterase, monoamine oxidases and β-amyloid aggregation inhibitory activities as potential agents against Alzheimer’s disease. Bioorg. Med. Chem. 2017, 25, 1997-2009.

4、Aurone mannich base derivatives as promising multifunctional agents with acetylcholinesterase inhibition, anti-β-amyloid aggregation and neuroprotective properties for the treatment of Alzheimer's disease. Eur. J. Med. Chem. 2017, 126, 762-775.

5、DL-3-n-butylphthalide-Edaravone hybrids as novel dual inhibitors of amyloid-β aggregation and monoamine oxidases with high antioxidant potency for Alzheimer’s therapy. Bioorg. Med. Chem. Lett. 2017, 27, 718-722.

6、Multitarget drug design strategy against Alzheimer’s disease: homoisoflavonoid mannich base derivatives serve as acetylcholinesterase and monoamine oxidase B dual inhibitors with multifunctional properties. Bioorg. Med. Chem. 2017, 25, 714-726.

7、Design, synthesis and biological evaluation of 4’-aminochalcone-rivastigmine hybrids as multifunctional agents for the treatment of Alzheimer's diseas. Bioorg. Med. Chem. 2017, 25, 1030-1041.

8、Scaffold hopping toward agomelatine: novel 3, 4-dihydroisoquinoline compounds as potential antidepressant agents. Sci. Rep., 2016, 6, 34711.

9、Synthesis and evaluation of 4-hydroxyl aurone derivatives as multifunctional agents for the treatment of Alzheimer’s disease. Bioorg. Med. Chem. 2016, 24, 2342-2351.

10、Pterostilbene-O-acetamidoalkylbenzylamines derivatives as novel dual inhibitors of cholinesterase with anti-β-amyloid aggregation and antioxidant properties for the treatment of Alzheimer’s disease. Bioorg. Med. Chem. Lett. 2016, 26, 2035-2039.

11、二鹽酸沙丙蝶呤的合成. 中國醫藥工業雜誌, 2016, 832-834.

12、奧貝膽酸及其有關物質的合成. 中國醫藥工業雜誌, 2016, 376-379.

13、Design, synthesis, and biological evaluation of scutellarein carbamate derivatives as potential multifunctional agents for the treatment of Alzheimer's disease. Chem. Bio. Drug Des. 2015, 86, 1168-1177.

14、利伐沙班的合成. 中國醫藥工業雜誌, 2015, 442-445.

15、Design, synthesis and evaluation of scutellarein-O-alkylamines as multifunctional agents for the treatment of Alzheimer's disease. Eur. J. Med. Chem. 2015, 94, 348-366.

16、Design, synthesis and evaluation of chromone-2-carboxamido-alkylbenzylamines as multifunctional agents for the treatment of Alzheimer’s disease. Bioorg. Med. Chem. 2015, 23, 911-923.

17、Multifunctional scutellarin-rivastigmine hybrids with cholinergic, antioxidant, biometal chelating and neuroprotective properties for the treatment of Alzheimer’s disease. Bioorg. Med. Chem. 2015, 23, 668-680.

18、Synthesis and evaluation of genistein-O-alkylbenzylamines as potential multifunctional agents for the treatment of Alzheimer’s disease. Eur. J. Med. Chem. 2014, 76, 314-331.

19、Therapeutic efficacy of a novel non-peptide alph v beta 3 integrin antagonist for pathological retinal angiogenesis in mice. Experimental Eye Research 2014, 129, 119-126.

20、Synthesis and biological evaluation of novel naphthalene compounds as potential antidepressant agents. Eur. J. Med. Chem. 2014, 82, 263-273.

21、Synthesis of major degradation products of the injection of linezolid. Chin. J. Org. Chem. 2014, 34, 989-993.

22、Synthesis of pterostilbene and resveratrol carbamate derivatives as potential dual cholinesterase inhibitors and neuroprotective agents. Res. Chem. Intermed. 2014, 40, 787-800.

23、4-(4-氨基苯基)-3-嗎啉酮的製備. 中國醫藥工業雜誌, 2014, 110-112.

24、A facile total synthesis of amorfrutin A. Tetrahedron Letters 2013, 54, 2658-2660.

25、Synthesis and biological evaluation of genistein carbamate derivatives. Chin. J. Org. Chem. 2013, 33, 621-629.

26、An improved synthesis of 1,2,6,7-tetrahydro -8H-indeno-[5,4-b]furan-8-one. Chin. J. Org. Chem. 2012, 32, 2368-2372.

27、Synthesis, characterization, antibacterial and antifungal evaluation of novel monosaccharide esters. Molecules 2012, 17, 8661-8673.

28、Synthesis and biological evaluation of 2-(3-fluoro-4-nitrophenoxy)-N-phenylacetamide derivatives as novel potential affordable antitubercular agents. Molecules 2012, 17, 2248-2258.

29、Synthesis of 2,4-diaminoquinazolines and tricyclic quinazolines by cascade reductive cyclization of methyl N-cyano-2-nitrobenzimidates. J. Org. Chem. 2012, 77, 2649-2658.

30、A novel synthesis of fidarestat. Chin. J. Org. Chem. 2011, 31, 1262-1265.

31、利奈唑胺的合成. 中國醫藥工業雜誌. 中國醫藥工業雜誌, 2011, 245-247.

32、(2S,3R,4S)-4-羥基異亮氨酸的不對稱合成. 中國醫藥工業雜誌, 2010, 491-494.

33、3-(2,3-二氫苯並呋喃-5-基)丙酸的合成. 中國醫藥工業雜誌, 2010, 14-16.

34、牛磺熊去氧膽酸的合成. 中國醫藥工業雜誌, 2009, 88-89. ^[1] 

1、一類黃酮烷基胺類化合物其製備方法和用途. WO 2014111004 A1.

2、一類金雀異黃酮烷基胺類化合物其製備方法和用途. WO 2014111028 A1.

3、五碳或六碳單糖-(E)-3-(呋喃-2-基)丙烯酸單酯類化合物及其製備方法和用途. WO 2012055146 A1.

4、1,3-噁唑烷-2-酮類化合物其製備方法和用途. WO 2012171248 A1.

5、非甾體雄激素受體調節劑及其製備方法、藥物組合物和用途. WO 2006125397 A1. ^[1]