江正強

1988.09-1992.07，中國農業大學食品科學專業，本科

1992.09-1995.03，中國農業大學食品學院，食品科學專業，碩士生

1998.09-2001.06，中國農業大學食品學院，食品科學專業，博士生

2005.09-2006.08，法國食品工業大學，博士後 ^[1] 

1995.04-2001.08，中國農業大學食品學院，助教，講師

1998.09-1999.04，日本神户大學，訪問學者

2000.04-2001.03，日本食品綜合研究所，聯合國大學特別研究員

2001.09-2004.11，中國農業大學食品學院，副教授

2010.02-2012.02，國家自然科學基金委員會，食品科學流動項目主任

2013.08-2013.10，德國呂貝克大學，德國教育部特邀訪問學者

2004.07-2014.08，德國呂貝克大學，德國教育部特邀訪問學者

2004.12-今，中國農業大學食品學院，教授 ^[1] 

長江學者特聘教授、國家傑出青年基金獲得者、萬人計劃、科技部中青年科技創新領軍人才、教育部新世紀優秀人才等。

擔任食品科學、中國農業科學、中國糧油學報等十多個學術期刊編委。

中國生物發酵產業協會，理事；中國食品科學技術學會酶製劑分會，常務理事；中國糧油學會發酵麪食分會，常務理事；中國農業工程學會農產品加工分會，常務理事；北京市食品學會，理事。 ^[1] 

本科生課程：《食品酶學與酶工程原理》

研究生課程：《酶和酶工程專題》等。 ^[1] 

研究領域：食品生物技術

（1）酶與發酵工程：新型食品酶發掘、基因的克隆和表達、酶製劑的發酵生產、純化、性質和應用；

（2）新酶的結構解析及分子改造：如新型葡聚糖酶、酯酶、幾丁質酶、蛋白酶等；

（3）食品營養與功能研究：利用生物技術製備功能性食品原料並進行功能評價，如功能性低聚糖及活性肽等；

（4）食品加工方向：低聚糖的生產和功能、傳統食品工業化和糧油加工等。 ^[1] 

主持國家級課題10餘項；著有專業著作4部，代表性專著如《酶與酶工程及其應用》和《焙烤食品工藝學(第2版)》。發表SCI收錄論文100多篇，引用1600次；授權國家發明專利40餘項。

主要科研項目

（1）科技部“十三五”國家重點研發計劃“現代食品加工及糧食收儲運技術與裝備”重點專項：食品營養及生物活性物質的健康功能作用研究

（2）國家自然科學基金重點項目：不同家族β-1,3-葡聚糖酶和β-甘露聚糖酶的作用機制及其製備低聚糖的益生活性構效關係

（3）國家自然科學基金面上項目：特異性幾丁質酶的催化機制、幾丁寡糖的高效製備及功能

（4）長江學者特聘教授：食品科學

（5）國家傑出青年科學基金：食品酶學

（6）科技部農業科技成果轉化資金項目：玉米芯高效轉化功能性糖技術應用示範 ^[1] 

著有專業著作4部，代表性專著《酶與酶工程及其應用》（副主編，主筆16萬字，2006年7月化學工業出版社出版）和《焙烤食品工藝學(第2版)》（副主編，主筆25萬字，2010年1月中國輕工業出版社出版）。

在國內外刊物發表學術論文150餘篇，其中SCI、EI收錄的論文70多篇。論文被引用600多次，全部SCI論文的h index為18，部分代表性SCI論文如下：

1. Peng Zhou, Zhongzhou Chen, Qiaojuan Yan, Shaoqing Yang, Rolf Hilgenfeld, Zhengqiang Jiang*. The structure of a glycoside hydrolase family 81 endo-β-1,3-glucanase. Acta Cryst., 2013, D69, 2027–2038. Impact Factor 14.103

2. Shaoqing Yang, Chengwei Hua, Qiaojuan Yan, Yinan Li, Zhengqiang Jiang*. Biochemical properties of a novel glycoside hydrolase family 1 β-glucosidase gene (PtBglu1) from Paecilomyces thermophila expressed in Pichia pastoris. Carbohydrate Polymers, 2013, 92(1):784–791. IF 3.628

3. Jianzhi Zhang, Narasimha Kumar Kopparapu, Qiaojuan Yan, Shaoqing Yang, Zhengqiang Jiang*. Purification and characterization of a novel chitinase from persimmon (Diospyros kaki) with antifungal activity. Food Chemistry, 2013, 138(2-3), 1225-1232. IF 2.823

4. Shaoqing Yang, Haibo Xu, Qiaojuan Yan, Yu Liu, Peng Zhou Zhengqiang Jiang*. A low molecular mass cutinase of Thielavia terrestris efficiently hydrolyzes Poly(esters). Journal of Industrial Microbiology & Biotechnology, 2013, 40 (2):217-226. IF 2.786

5. Priti Katrolia, Qiaojuan Yan, Pan Zhang, Peng Zhou, Shaoqing Yang, Zhengqiang Jiang*. Gene cloning and enzymatic characterization of an alkali-tolerant endo-1,4-β-mannanase from Rhizomucor miehei. J Agric Food Chem. 2013, 61(2):394-401. IF 2.823

6. Peng Han, Peng Zhou, Songqing Hu, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang*. A novel multifunctional α-amylase from the thermophilic fungus Malbranchea cinnamomea: Biochemical characterization and three-dimensional structure. Applied Biochemistry and Biotechnology, 170, 420-435. IF 1.893

7. Priti Katrolia, Peng Zhou, Pan Zhang, Qiaojuan Yan, Yinan Li, Zhengqiang Jiang*, Haibo Xu. High level expression of a novel β-mannanase from Chaetomium sp. exhibiting efficient mannan hydrolysis. Carbohydrate Polymers, 2012, 87(1)480-490. IF 3.628

8. Narasimha Kumar Kopparapu, Shuping Zhang, Peng Zhou, Qiaojuan Yan, Zhengqiang Jiang*, Zhuqing Liu. Purification and characterization of a novel chitinase gene from Paecilomyces thermophila expressed in Escherichia coli. Carbohydrate Research, 2012, 347 (1) 155–160. IF2.332

9. Qiaojuan Yan, Luo Tang, Shaoqing Yang, Shuping Zhang, Zhengqiang Jiang*. Purification and characterization of a novel thermostable α-L-arabinofuranosidase (α-L-AFase) from Chaetomium sp. Process Biochemistry, 2012, 47 (3) 472-478. IF2.627

10. Linhua Huang, Qiaojuan Yan, Narasimha Kumar Kopparapu, Zhengqiang Jiang*, Yan Sun. Astragalus membranaceus lectin (AML) induces caspase-dependent apoptosis in human leukemia cells. Cell Proliferation, 2012, 45(1), 15-21. IF: 2.521

11. Yanbin Tang, Shaoqing Yang, Qiaojuan Yan, Peng Zhou, Jian Cui, Zhengqiang Jiang*. Purification and characterization of a novel β-1,3-1,4-glucanase (lichenase) from the thermophilic Rhizomucor miehei with high specific activity and its gene sequence. J. Agric. Food Chem., 2012, 60 (9), pp 2354–2361 IF 2.823

12. Priti Katrolia, Huiyong Jia, Qiaojuan Yan, Shuang Song, Zhengqiang Jiang*, Haibo Xu. Characterization of a protease-resistant α-galactosidase from the thermophilic fungus Rhizomucor miehei and its application in removal of raffinose family oligosaccharides. Bioresource Technology, 2012 (110), 578-586. IF4.98

13. Huiyong Jia, Guangsen Fan, Qiaojuan Yan, Yuchun Liu, Ye Yan, Zhengqiang Jiang*. High-level expression of a hyperthermostable Thermotoga maritima xylanase in Pichia pastoris by codon optimization. Journal of Molecular Catalysis B: Enzymatic, 2012, 78, 72-77. IF 2.735

14. Huiyong Jia, Yinan Li, Yuchun Liu, Qiaojuan Yan, Shaoqing Yang, Zhengqiang Jiang*. Engineering a thermostable β-1,3-1,4-glucanase from Paecilomyces thermophila to improve catalytic efficiency at acidic pH. Journal of Biotechnology 2012, 159 (1-2), 50-55. IF3.045

15. Yan Qiaojuan, Chengwei Hua, Shaoqing Yang, Yinan Li, Zhengqiang Jiang*. High level expression of extracellular secretion of a β-glucosidase gene (PtBglu3) from Paecilomyces thermophila in Pichia pastoris. Protein Expression and Purification, 2012, 84, 64-72. IF1.587

16. Guangsen Fan, Huiyong Jia, Katrolia Priti, Shaoqing Yang, Qiaojuan Yan, Zhengqiang Jiang*. High-level expression of a xylanase gene from the thermophilic fungus Paecilomyces thermophila in Pichia pastoris. Biotechnology Letters, 2012, 34 (11):2043-2048. IF1.853

17. Zhou Chen, Huiyong Jia, Yu Yang, Qiaojuan Yan, Zhengqiang Jiang* and Chao Teng. Secretory expression of a β-xylosidase gene from Thermomyces lanuginosus in Escherichia coli and characterization of its recombinant enzyme. Letters in Applied Microbiology, 2012, 55(5):330–337. IF 1.629

18. Teng C, Jia HY, Yan QJ, Zhou P, Zhengqiang Jiang*. High-level expression of extracellular secretion of a β-xylosidase gene from Paecilomyces thermophila in Escherichia coli. Bioresource Technology, 2011, 102(2): 1822-1830. IF 4.75

19. Kopparapu NK, Liu ZQ, Yan QJ, Zhengqiang Jiang*, Zhang SP. A novel thermostable chitinase (PJC) from pomegranate (Punica granatum) juice. Food Chemistry, 2011, 127(4): 1569-1575. IF 3.334

20. Zhou P, Zhu HF, Yan QJ, Katrolia P, Zhengqiang Jiang*. Purification and properties of a Psychrotrophic Trichoderma sp. xylanase and its gene sequence. Applied Biochemistry and Biotechnology, 2011, 164(6): 944-956. IF 1.893

21. Kopparapu NK, Liu ZQ, Fei F, Yan QJ, Zhengqiang Jiang*. Purification and characterization of a chitinase (sAMC) with antifungal activity from seeds of Astragalus membranaceus. Process Biochemistry, 2011, 46(6): 1370-1374. IF 2.414

22. Katrolia P, Yan QJ, Jia HY, Li YN, Zhengqiang Jiang*, Song CL. Molecular cloning and high-level expression of a β-galactosidase gene from Paecilomyces aerugineus in Pichia pastoris. Journal of Molecular Catalysis B-Enzymatic, 2011, 69(3-4): 112-119. IF 2.823

23. Katrolia P, Zhang M, Yan QJ, Zhengqiang Jiang*, Song CL, Li LT. Characterisation of a thermostable family 42 β-galactosidase (BgalC) family from Thermotoga maritima showing efficient lactose hydrolysis. Food Chemistry, 2011, 125(2): 614-621. IF 3.334 ^[2] 

Shaoqing Yang, Qiaojuan Yan, Qingdan Bao, Jingjing Liu, &Zhengqiang Jiang*. Expression and biochemical characterization of a novel type I pullulanase from Bacillus megaterium. Biotechnology Letters, 2017, 39:397-405.

Xia Wu, Jing Wang, Yuqin Shi, Sai Chen, Qiaojuan Yan, Zhengqiang Jiang*, &Hao Jing. N -Acetyl-chitobiose ameliorates metabolism dysfunction through Erkp38 MAPK and histone H3 phosphorylation in type 2 diabetes mice. Journal of Functional Foods. 2017, 28:96-105.

Shaoqing Yang, Xin Fu, Qiaojuan Yan, Zhengqiang Jiang*, &Jing Wang. Biochemical characterization of a novel acidic exochitinase from Rhizomucor miehei with antifungal activity. Journal of Agricultural and Food Chemistry. 2016, 64:461-469.

Shaoqing Yang, Xing Fu, Qiaojuan Yan, Yu Guo, Zhuqing Liu, &Zhengqiang Jiang*. Cloning，expression, purification and application of a novel chitinase from a thermophilic marine bacterium Paenibacillus barengoltzii. Food Chemistry. 2016, 192:1041-1048.

Jingjing Liu, Yu Liu, Feng Yan, Zhengqiang Jiang, Shaoqing Yang*, &Qiaojuan Yan*. Gene cloning, functional expression and characterisation of a novel type I pullulanase from Paenibacillus barengoltzii and its application in resistant starch production. Protein Expression and Purification. 2016, 121: 22-30.

Zhen Qin, Qiaojuan Yan*,Shaoqing Yang, &Zhengqiang Jiang*. Modulating the function of a β-1,3-glucanosyltransferase to that of an endo-β-1,3-glucanase by structure-based protein engineering. Applied Microbiology and Biotechnology. 2016, 100:1765-1776.

Zhen Qin，Yibei Xiao，Xinbin Yang, Jeroen R. Mesters, Shaoqing Yang, &Zhengqiang Jiang*. A unique GCN5-related glucosamine N-acetyltransferase region exist in the fungal multidomain glycoside hydrolase family 3 β-N-acetylglucosaminidase. Scientific Reports. 2015, 5:18292.

Zhou Chen, Yu Liu, Qiaojuan Yan*, Shaoqing Yang, &Zhengqiang Jiang*. Biochemical characterization of a novel endo-1,5-α‑L‑arabinanase from Rhizomucor miehei. Journal of Agricultural and Food Chemistry. 2015, 63:1226-1233.

Yanxiao Li, Yu Liu, Qiaojuan Yan*, Shaoqing Yang, &Zhengqiang Jiang*. Characterization of a novel glycoside hydrolase family 5 β-mannosidase from Absidia corymbifera with high transglycosylation activity. Journal of Molecular Catalysis B: Enzymatic. 2015, 122:265-274.

Haibo Xu, Qiaojuan Yan, Xiaojie Duan, Shaoqing Yang*, &Zhengqiang Jiang*. Characterization of an acidic cold-adapted cutinase from Thielavia terrestris and its application in flavor ester synthesis. Food Chemistry. 2015, 188:439-445.

Xiaoyan You, Hui Wang, Guangyue Ren, Jingjing Li, Xu Duan, Huajun Zheng, &Zhengqiang Jiang*. Complete genome sequence of the molybdenum-resistant bacterium Bacillus subtilis strain LM 4-2. Standards in Genomic Sciences. 2015, 10:127.

Zhen Qin, Qiaojuan Yan, Qingjun Ma, &Zhengqiang Jiang*. Crystal structure and characterization of a novel L-serine ammonia-lyase from Rhizomucor miehei. Biochemical and Biophysical Research Communications. 2015, 466:431-437. ^[1] 

授權發明專利20餘項，代表性10項如下：

1. 江正強, 賈會勇, 閆巧娟, 李一男, 陳洲. 獲得定向突變基因的方法和基於其發現的酸性β-1,3-1,4-葡聚糖酶[P]. 北京：CN103045560A, 2013-04-17.

2. 江正強, 賈會勇, 閆巧娟, 波利特, 宋爽. 一種α-半乳糖苷酶及其編碼基因和應用[P]. 北京：CN103045562A, 2013-04-17.

3. 江正強, 華承偉, 楊紹青, 閆巧娟, 李一男. 一種β-葡萄糖苷酶及其編碼基因與應用[P]. 北京：CN102477417A, 2012-05-30.

4. 江正強, 張敏, 波麗特, 宋春雷, 李裏特. 一種耐高温β-半乳糖苷酶及其編碼基因與應用[P]. 北京：CN101993864A, 2011-03-30.

5. 江正強, 杜雪丹, 閆巧娟, 唐豔斌. 一種製備β-葡聚糖酶的方法及其專用菌株[P]. 北京：CN101845423A, 2010-09-29.

6. 江正強, 賈會勇, 滕超, 周鵬, 閆巧娟. β-木糖苷酶及其編碼基因與應用[P]. 北京：CN101724615A, 2010-06-09.

7. 江正強, 楊紹青, 閆巧娟, 王嵐. 製備耐熱木聚糖酶、耐熱β-木糖苷酶或耐熱β-葡萄糖苷酶的方法[P]. 北京：CN101012457, 2007-08-08.

8. 江正強, 李裏特, 李道義, 朱運平. 一種生產木二糖的方法及其專用固定化酶[P]. 北京：CN1916171, 2007-02-21.

9. 江正強, 武愛民, 閆巧娟, 韋贇, 叢倩千. 一種生產甘露聚糖酶的方法及其專用固定化生物膜[P]. 北京：CN101492667, 2009-07-29.

10. 江正強, 郭洋, 閆巧娟, 滕超. 一種利用玉米芯生產L-乳酸的方法及其專用米根黴[P]. 北京：CN101724663A, 2010-06-09. ^[2] 

榮獲國家傑出青年基金、光華工程科技獎1項、中國青年科技獎1項、國家科技發明二等獎1項、國家科技進步二等獎1項、省部級科技進步二等獎2項和國際學術獎2項；另外博士論文獲“全國優秀百篇博士論文”，入選教育部“新世紀優秀人才”。

獲國家科技進步二等獎、國家科技發明二等獎各1項；中國青年科技獎；光華工程科技獎；科技部中青年科技創新領軍人才（2014）、國家傑出青年科學基金（2013）、光華工程科技獎（2012）、中國青年科技獎（2010）、教育部新世紀優秀人才（2005）、全國優秀百篇博士論文（2005）等；獲省部級獎勵3項和國際學術獎2項。 ^[1] 

2022年5月30日，榮獲第十四屆光華工程科技獎。 ^[4]