楊定喬

2010,07-2010,12,美國紐約城市大學（City University of New York）做研究，訪問教授。

2005,10-2006,04，美國阿肯色州大學（University of Akansas）從事藥物研究半年。訪問教授。

2002,02-2003,03.加拿大多倫多大學（University of Toronto）化學系從事不對稱催化有機合成研究工作一年，訪問教授.

1991年，1993年，1996年,曾三次應邀赴美國新澤西州立大學講學並從事科研達二年以上。訪問學者.

1985年-1988年．延邊大學化學系,有機合成專業研究生。 ^[1] 

不對稱催化有機合成和雜環藥物合成。

（1） 不對稱催化有機合成 採用銠,銥和鉑與雙膦配體組成的絡合物作為手性催化劑，進行氧（氮）雜苯並降冰片烯與親核試劑的不對稱開環反應的研究，獲得較高的立體化學選擇性及對映選擇性，得到對映體過量值為95-99% ee的好結果。因此這項研究對於尋找新的手性催化劑和開發新的手性藥物，豐富過渡金屬不對稱催化立體化學將具有重大科學意義。

（2） 雜環藥物合成 很多喹啉衍生物具有殺菌、抗菌、抗高血壓、抗抑鬱、抗過敏、抗瘧疾、抗腫瘤和抗癌等生物活性和藥理活性。通過改變喹啉環上的取代基來修飾結構，探索新的喹啉類化合物合成方法及新的藥物合成。 ^[1] 

主要論文：

1. Wen Yang, Guo Cheng, Yue Li, Xiongjun Zuo,Dingqiao Yang*. Iridium-catalyzed Anti-Stereoselective Ring-Opening Reactions of Azabicyclic Alkenes with Fluoroalkylamines.Synthesis。

2. Ruihua Wu, Wen Yang, Wenkun Chen,Dingqiao Yang*. Platinum-catalyzed syn-stereocontrolled ring-opening of oxabicyclic alkenes with sodium arylsulfinates.Org. Chem. Front.。

3. Guo Cheng, Wen Yang, Yue Li,Dingqiao Yang*. Iridium/Copper Co-catalyzed Anti-Stereoselective Ring Opening of Oxabenzonorbornadienes with Grignard Reagents.J. Org. Chem.

4. Wei Guo, Lvyin Zheng, Yongdong Li, Renmiao Wu, Qiang Chen,Dingqiao Yang*, Xiaolin Fan. Discovery of molluscicidal and cercaricidal activities of 3-substituted quinazolinone derivatives by a scaffold hopping approach using apseudo-ring based on the intramolecular hydrogen bond formation.Eur. J. Med. Chem.

5. Yue Li, Wen Yang, Guo Cheng,Dingqiao Yang*. Palladium-Catalyzed syn-Stereocontrolled Ring-Opening of Oxabicyclic Alkenes with Sodium Arylsulfinates.J. Org. Chem.

6. Guobao Huang, Zhenfeng He, Chen-Xi Cai, Fangfang Pan,Dingqiao Yang*, Kari Rissanend, Wei Jiang*. Bis-urea macrocycles with a deep cavity.Chem. Commun.

7. Wen Yang, Renshi Luo,Dingqiao Yang*. Iridium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes with N-Substituted Piperazine Nucleophiles.Molecules

8.Ling Meng, Wen Yang, Xuejing Pan, Meng Tao, Guo Cheng, Sanyong Wang, Heping Zeng, Yuhua Long*,Dingqiao Yang*.Platinum-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadienes with Phenols.J. Org. Chem.

9. Zhongyi Zeng,Dingqiao Yang*, Yuhua Long, Xuejing Pan, Guobao huang, Xiongjun Zuo, Wen Wei. Nickel-Catalyzed Asymmetric Ring Opening of Oxabenzonorbornadienes with Arylboronic Acids.J. Org. Chem.

10. Pen Xuejing,Dingqiao Yang*. Platium-Catalyzed Asymmetric Ring-Opening Addition of Arylboronic Acids to Oxabenzonorbornadienes.J. Org. Chem.

11.Dingqiao Yang*, Ni Liang.Platinum-Catalyzedanti-StereocontrolledRing-Opening of Oxabicyclic Alkenes with Grignard Reagents.Org. Biomol. Chem.

12.Yuhua Long, Wenling Wang,Dingqiao Yang,Han Jiang, Kaixua Chen, Yali Fang.Iridium-catalyzed asymmetric ring-opening reactions of azabenzonorbornadiene with carboxylic acid nucleophiles.Mol Divers,

13.Yuhua Long, Xiaolu Li, Xuejing Pan, Dandan Ding, Xuan Xu, Xiongjun Zuo,Dingqiao Yang*etal. Iridium-Catalyzed Asymmetric Ring-Opening of Oxabicyclic Alkenes with carboxylic Acids.Catal. Lett.

14.Dingqiao Yang*, etal. Iridium-Catalyzed Asymmetric Ring-Opening of Azabicyclic Alkenes with Alcohols,Org. Biomol. Chem.

15. Yuhua Long, Haifeng. Zhang,Dingqiao Yang*. Efficient Synthesis of Ferrocenyl Quinolines via the Friedlander Reaction,Synth. Commun.

16.Dingqiao Yang*, etal. A Facile Synthesis of 9,10-Dimethoxybenzo[6,7]-Oxepino[3,4-b]quinolin-13(6H)-one and its Derivatives.Intel. J. Org. Chem.

17. Hanchao Cheng,Dingqiao Yang*.Iridium-Catalyzed Asymmetric Ring-Opening of Oxabenzonorbornadienes with Phenols.J. Org. Chem.

18.Dingqiao Yang, Satvika Burugupalli, David Daniel, and Yu Chen. Microwave-Assisted One-PotSynthesis of Isoquinolines, Furopyridines, and Thienopyridines by Palladium-Catalyzed Sequential Coupling–Imination–Annulation of 2-Bromoarylaldehydes with Terminal Acetylenes and AmmoniumAcetate.J. Org. Chem,

19. Shai Fang, Xiuli Liang, Yuhua Long, Xiaolu Li,Dingqiao Yang*, Sanyong Wang, and Chunrong Li. Iridium-Catalyzed Asymmetric Ring-Opening of Azabicyclic Alkenes with Phenols.Organometallics

20.Dingqiao Yang,* Yuhua Long, Huan Wang, and Zhenming Zhang, Iridium-Catalyzed Asymmetric Ring-Opening Reactions of N-Boc-azabenzonorbornadiene with Secondary Amine Nucleophiles.Org. Lett.

21.Dingqiao Yang,* Yuhua Long,* Junfang Zhang, Heping Zeng, Sanyong Wang, and Chunrong Li. Iridium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadienes with Amine Nucleophiles.Organometallics

22.Dingqiao Yang,* Yuhua Long,*Yujuan Wu, Xiongjun Zuo, Qingqiang Tu, Shai Fang, Lasheng Jiang, Sanyong Wang, and Chunrong Li. Iridium-Catalyzed Anti-Stereocontrolled Asymmetric Ring Opening ofAzabicyclic Alkenes with Primary Aromatic Amines.Organometallics

23. Yuhua Long,Dingqiao Yang,* Zhenming Zhang, Yujuan Wu, Heping Zeng, and Yu Chen. Iridium-Catalyzed Asymmetric Ring Opening of Azabicyclic Alkenes by Amines.J. Org. Chem.

24. Yuhua Long, Shuangqi Zhao, Heping Zeng,Dingqiao Yang*. Highly Efficient Rhodium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabenzonorbornadiene with Amine Nucleophiles,Catal. Lett.

25. Mark Lautens, F. K,Dingqiao Yang. Rhodium-Catalyzed Asymmetric Ring-Opening Reactions of Oxabicyclic Alkenes: The Application of Halide Effects in the Development of a General Process.J. Am.Chem. Soc.

26. Yahui Feng, Jingning Li, Lasheng Jiang, Zhihong Cai, Weicong Huang, Fei Jiang, Nianhua Luo, Shujuan Han, Ronghua Zeng,Dingqiao Yang.Efficient Syntheses and Complexation Studies of Diacetylene-Containing Macrocyclic Polyethers.Eur. J. Org. Chem.

27. Long, Yuhua,Yang, Dingqiao*, Zeng, Heping, Xie, Lei, Wu, Lihuan, Mo, Haihong, Zuo, Xiongjun.Rhodium-catalyzed Asymmetric Ring-opening Reactions of N-Boc-azabenzonorbornadiene withN-Substituted Piperazine Nucleophiles.Chin. J. Chem.

28.Dingqiao Yang*, Ping Hu, Yuhua Long, Yujuan Wu, Heping Zeng, Hui Wang and Xiongjun Zuo. Iridium-catalyzed asymmetric ring-opening reactions of oxabicyclic alkenes with secondary amine nucleophiles.Beilstein J. Org. Chem.

29. Gong-chang Zeng, Xin-hua Ouyang,Dingqiao Yang,He-ping Zeng,. A promising strategy for two-photon absorption materials by novel dicarbazole-conjugated C₆₀/C₇₀fullerene derivatives.Optical Materials

30.Dingqiao Yang,Haifeng Zhang, Qian Ming Wang.Photophysical properties of novel ferrocenyl quinoline derivatives with red emission in solutions and polymeric matrices.Chemical Papers

31. Liu Yang, Xiaoyun Ma, Anne Lyone, Junhui Zou, Michael L. Blankbun, Jing Pan,Dingqiao Yang*.Proper expression of helix–loop–helix protein Id2 is important to chondrogenic differentiation of ATDC5 cells.Biochem. J.

32.Dingqiao Yang*,Wei Guo, Yuepeng Cai, Lasheng Jiang, Kailing Jiang, Xiaobing Wu. Efficient synthesisof novel six-member ring-fused quinoline derivatives via the friedländer reaction.HeteroatomChem.

33. Xiuxia Zhou, Maosheng Liu, Xiaoming Lin, Huacai Fang, Jianqiao Chen,Dingqiao Yang, Yuepeng Cai. Construction of three low dimensional Zn (II) complexes based on different organic-carboxylic acids.Inorganica Chimica Acta,

34.Dingqiao Yang*, Kailin Jiang, Jingning Li, Feng Xu. Synthesis and Characterization of quinoline derivaties via the Friedlander reaction.Tetrahedron

35. Sanyong Wang, Weiwei Mao, Zhigang She, Chun-rong Li,Dingqiao Yang, Yongcheng Lin and Liwu Fu, Synthesis and biological evaluation of 12 allenic aromatic ethers.Bioorg.&Med. Chem.Lett.

36. Zhong Li,Dingqiao Yang, Reinhard Gabathuler, Qingqi Chen. Synthesis of novel heterobifunctionalisocyanato cross-linkers and their applications for the preparation of 10-hydroxycamptothecin and SN-38 conjugates with melanotransferrin.Synth. Commun.

主要專利：

Wang, Sanyong.; Li, Chunrong.; Duan, Zebin.;Yang, Dingqiao. Method for chiral synthesis of L-menthol,Faming Zhuanli Shenqing,

主要項目：

1．2007年，國家自然科學基金面上項目; 新型手性雙膦配體設計合成及銥不對稱催化開環反應研究。項目主持人。

2. 2011年，國家自然科學基金面上項目; 鉑催化雜原子二環烯烴不對稱開環反應的研究。項目主持人。

3. 2008年，廣東省自然科學基金重點項目; 銥不對稱催化開環反應基礎研究。項目主持人。

4. 2013年，國家自然科學基金面上項目; 鎳催化氧雜（氮雜）苯並降冰片烯與碳負離子親核試劑的不對稱開環反應的研究. 項目主持人。

5.2013年，廣東省自然科學基金重點項目; 鎳催化不對稱開環反應的基礎研究, 項目主持人。

主要著作：

1.楊定喬 汪朝陽 龍玉華 編《高等有機化學》北京;化學工業出版社,

2.楊定喬 主編,朱育林 龍玉華 副主編《有機化學實驗》北京;化學工業出版社,

3.李景寧 主編, 楊定喬 張前 副主編《有機化學》(第五版)北京;高等教育出版社,

4.陳清奇 楊定喬 陳新 編《新藥化學全合成路線手冊》北京;科學出版社,

5.楊定喬 龍玉華王升富 編《化學化工專業英語》北京;化學工業出版社,

6.楊定喬 參編“十一五”國家級規劃教材《化學合成實驗》北京;高等教育出版社,

7.楊定喬主編《精細有機品化學》北京; 石油大學出版社, ^[1]