劉劍鋒

2002.9–2005.6，中國農業大學，動物遺傳育種與繁殖，博士；

1993.9–1996.6，中國農業大學 （原北京農業大學），動物遺傳育種與繁殖，碩士；

1989.9–1993.6，中國農業大學 （原北京農業大學），動物遺傳育種與繁殖，學士 ^[1] 

2008.11- 至今，中國農業大學，動物科技學院，副教授（中國農業大學“優秀引進人才”）、教授、副院長 ^[2]  ；

2005.8-2008.7，密蘇里大學堪薩斯校區醫學院，博士後、研究助理；

1996.6-2005.7，中國農業科學院，畜牧獸醫研究所，副研究員 ^[1] 

中國畜牧獸醫學會動物遺傳育種學分會、信息技術分會理事；

《Frontiers in Statistical Genetics and Methodology》、《PLoS ONE》期刊編委；

《Heredity》、《Bioinformatics》、《BMC Genomics》、《BMC Genetics》、《BMC Bioinformatics》、《Genetica》同行審稿人。 ^[1] 

主要致力於數量遺傳學、生物信息學理論和計算技術研究；基於多組學信息進行畜禽複雜性狀遺傳機理解析；以豬和奶牛為研究對象進行常規育種和組學信息相結合的優化策略研究（基因組選擇技術等）。 ^[1] 

《畜禽基因組學》（博士研究生學位課程，主講）

《統計遺傳學》 （碩士研究生學位課程，參講）

《動物育種原理和方法》（碩士研究生學位課程，參講）

《畜牧生物統計與試驗設計》（本科生必修課程，主講） ^[1] 

2011.1-2015.12 科技部“863”優先主題項目“基於高密度SNP芯片的牛、豬基因組選擇”（2011AA100302）子課題主持人；

2013.1-2016.12 主持國家自然科學基金“基於測定日模型建立中國荷斯塔奶牛基因組選擇新方法”（31272419）；

2014.1-2016.12主持國家科技重大專項“奶牛產奶性能相關基因的克隆和功能驗證”（2014ZX0800953B）；

2013.1-2017.12國家863計劃“中國地方豬種生長、繁殖力等優異性狀基因組學研究”（2013AA102503），參加；

2014.1-2016.12國家科技重大專項影響仔豬免疫力候選基因的克隆和功能驗證（2014ZX0800945B），參加人。 ^[1] 

1. Fang M., Liu J., Sun D., Zhang Y., Zhang Q. & Zhang S. (2011) QTL mapping in outbred half-sib families using Bayesian model selection. Heredity 107, 265-76.

2. Fu W.X., Liu Y., Lu X., Niu X.Y., Ding X.D., Liu J.F. & Zhang Q. (2012) A genome-wide association study identifies two novel promising candidate genes affecting Escherichia coli F4ab/F4ac susceptibility in swine. PLoS One 7, e32127.

3. Fu W.X., Wang C.L., Ding X.D., Zhang Z., Ma P.P., Weng Z.Q., Liu J.F. & Zhang Q. (2012) Genome-wide association analyses of the 15th QTL-MAS workshop data using mixed model based single locus regression analysis. BMC Proc 6 Suppl 2, S5.

4. Jiang J.C., Jiang L., Zhou B., Fu W.X., Liu J.F. & Zhang Q. (2011) Snat: a SNP annotation tool for bovine by integrating various sources of genomic information. Bmc Genetics 12.

5. Jiang J., Wang J., Wang H., Zhang Y., Kang H., Feng X., Yin Z., Bao W., Zhang Q. & Liu J.F. (2014) Global copy number analyses by next generation sequencing provide insight into pig genome variation. BMC Genomics 15, 593.

6. Jiang J., Zhang Q., Ma L., Li J., Wang Z. & Liu J.F. (2015) Joint prediction of multiple quantitative traits using a Bayesian multivariate antedependence model. Heredity 115, 29-36.

7. Jiang L., Jiang J., Yang J., Liu X., Wang J., Wang H., Ding X., Liu J. & Zhang Q. (2013) Genome-wide detection of copy number variations using high-density SNP genotyping platforms in Holsteins. BMC Genomics 14, 131.

8. Jiang L., Liu J., Sun D., Ma P., Ding X., Yu Y. & Zhang Q. (2010) Genome wide association studies for milk production traits in Chinese Holstein population. PLoS One 5, e13661.

9. Liu J., Liu Y., Liu X. & Deng H.W. (2007) Bayesian mapping of quantitative trait loci for multiple complex traits with the use of variance components. American Journal of Human Genetics 81, 304-20.

10.Liu J., Papasian C. & Deng H.W. (2007) Incorporating single-locus tests into haplotype cladistic analysis in case-control studies. Plos Genetics 3, e46.

11.Liu J., Pei Y., Papasian C.J. & Deng H.W. (2009) Bivariate association analyses for the mixture of continuous and binary traits with the use of extended generalized estimating equations. Genetic Epidemiology 33, 217-27.

12.Liu J., Zhang Y., Zhang Q., Wang L. & Zhang J. (2006) Study on mapping quantitative trait loci for animal complex binary traits using Bayesian-Markov chain Monte Carlo approach. Sci China C Life Sci 49, 552-9.

13.Lu X., Fu W.X., Luo Y.R., Ding X.D., Zhou J.P., Liu Y., Liu J.F. & Zhang Q. (2012) Genome-wide association study for T lymphocyte subpopulations in swine. BMC Genomics 13, 488.

14.Lu X., Liu J., Fu W., Zhou J., Luo Y., Ding X., Liu Y. & Zhang Q. (2013) Genome-wide association study for cytokines and immunoglobulin G in swine. PLoS One 8, e74846.

15.Lu X., Liu J.F., Gong Y.F., Wang Z.P., Liu Y. & Zhang Q. (2011) Mapping quantitative trait loci for T lymphocyte subpopulations in peripheral blood in swine. Bmc Genetics 12, 79.

16.Ma Y., Wei J., Zhang Q., Chen L., Wang J., Liu J. & Ding X. (2015) A genome scan for selection signatures in pigs. PLoS One 10, e0116850.

17.Pan D., Zhang S., Jiang J., Jiang L., Zhang Q. & Liu J. (2013) Genome-wide detection of selective signature in Chinese Holstein. PLoS One 8, e60440.

18.Wang H., Jiang L., Liu X., Yang J., Wei J., Xu J., Zhang Q. & Liu J.F. (2013) A post-GWAS replication study confirming the PTK2 gene associated with milk production traits in Chinese Holstein. PLoS One 8, e83625.

19.Wang H., Jiang L., Wang W., Zhang S., Yin Z., Zhang Q. & Liu J.F. (2014) Associations between variants of the HAL gene and milk production traits in Chinese Holstein cows. Bmc Genetics 15, 125.

20.Wang H., Wang J., Sun S., Wang Y., Guo J., Ning C., Yang K. & Liu J.F. (2015) Identification of reference microRNAs for quantitative expression analysis in porcine peripheral blood mononuclear cells treated with polyinosinic-polycytidylic acid. International Journal of Immunogenetics 42, 217-25.

21.Wang J., Jiang J., Fu W., Jiang L., Ding X., Liu J.F. & Zhang Q. (2012) A genome-wide detection of copy number variations using SNP genotyping arrays in swine. BMC Genomics 13, 273.

22.Wang J., Jiang J., Wang H., Kang H., Zhang Q. & Liu J.F. (2014) Enhancing genome-wide copy number variation identification by high density array CGH using diverse resources of pig breeds. PLoS One 9, e87571.

23.Wang J., Jiang J., Wang H., Kang H., Zhang Q. & Liu J.F. (2015) Improved Detection and Characterization of Copy Number Variations Among Diverse Pig Breeds by Array CGH. G3 5, 1253-61.

24.Wang J., Wang H., Jiang J., Kang H., Feng X., Zhang Q. & Liu J.F. (2013) Identification of genome-wide copy number variations among diverse pig breeds using SNP genotyping arrays. PLoS One 8, e68683.

25.Wang J.Y., Luo Y.R., Fu W.X., Lu X., Zhou J.P., Ding X.D., Liu J.F. & Zhang Q. (2013) Genome-wide association studies for hematological traits in swine. Anim Genet 44, 34-43.

26.Zhou C., Liu Z., Liu Y., Fu W., Ding X., Liu J., Yu Y. & Zhang Q. (2013) Gene silencing of porcine MUC13 and ITGB5: candidate genes towards Escherichia coli F4ac adhesion. PLoS One 8, e70303. ^[1] 

一種與中國荷斯坦奶牛產奶性狀及體細胞數評分相關的SNP標記及其應用

軟件著作（第一排名）：

貝葉斯A+基因組選擇計算軟件V1.0 (2014SRBJ0546)

多性狀貝葉斯Cπ基因組選擇計算軟件V1.0 (2014SRBJ0006)

基於貝葉斯前相關模型的多性狀基因組選擇計算軟件 (V1.02014SRBJ0480)

貝葉斯Lasso基因組選擇計算軟件V1.0 (2013SRBJ0778)

貝葉斯Cπ+基因組選擇計算軟件V1.0 (2013SRBJ0007)

多性狀貝葉斯A基因組選擇計算軟件V1.0 (2013SRBJ0824)

貝葉斯B+基因組選擇計算軟件V1.0 (2013SRBJ0547)

肉牛雜交遺傳評估系統V1.0 (2010SRBJ5812)

牛基因組單核苷酸多態性單機註釋系統V1.0 (2011SRBJ2797)

牛基因組單核苷酸多態性在線註釋系統V1.0 (2011SRBJ2798) ^[1] 

安徽省科技進步三等獎（2011年）

教育部新世紀人才（2012年） ^[1]