趙新

1972年7月出生於雲南。1994年7月畢業於北京師範大學化學系，獲理學學士學位。2003年7月畢業於中科院上海有機化學研究所，獲理學博士學位。2003年8月至2008年3月在美國哈佛大學化學與化學生物學系和芝加哥大學化學系從事博士後研究。2008年5月任中國科學院上海有機所創新崗位副研究員，課題組長；2014年3月晉升為研究員。2010年入選上海市“浦江人才計劃”。2017年獲國家傑出青年科學基金。 ^[1] 

超分子化學已經從物理有機化學的一個相對獨立的前沿分支，發展成為一個高度交叉融合的學科，除了其本身的有機化學研究外， 它在有機功能材料、生命體系等領域也得到了廣泛的應用。本課題組的研究主要集中在有機超分子組裝、結構與功能。自組裝是組裝基元（模塊）通過弱相互作用自發地形成有序結構的過程，是創造新物質和產生新功能的重要手段。以有機合成為基礎，以現代光譜、電子顯微鏡、電化學等多種表徵測試手段為工具，通過設計合成一些結構從簡單到複雜、帶有特定功能或分子識別位點的有機分子作為超分子組裝模塊，利用它們可控地自組裝構築一系列結構非常有序的一維、二維和三維超分子自組裝體系，從而實現一些特定的功能如生物模擬、分子識別、超分子催化以及功能化軟物質材料構建等。

主要進行以下研究課題： 1、新型π共軛體系的設計與合成：利用有機合成為基本手段構築各種新穎的共軛結構化合物（芳環和芳雜環等），發展新型功能組裝基元。 2、基於有機共軛分子的自組裝體系構建與軟物質功能材料：利用π共軛體系作為基本結構單元，通過多種非共價弱相互作用如芳香堆積、氫鍵、範德華力等協同作用，自組裝形成形態尺寸可調控、功能化的一維、二維或三維微米/納米尺度有序超分子體系。 3、超分子體系物理有機化學：自組裝體系的協同效應、熱力學和動力學行為、非共價鍵的本質與規律研究等，探索實現對自組裝過程的有效調控方法。 4、基於手性自組裝的超分子催化劑設計及其在不對稱催化反應中的作用機理和應用：通過自組裝形成的手性超分子體系所提供的手性環境來誘導產生化學鍵形成時的立體選擇性，從而達到不對稱催化的目的。 ^[2] 

（1）Feng Lin, Tian-Guang Zhan, Tian-You Zhou, Kang-Da Zhang, Guang-Yu Li, Jiang Wu, Xin Zhao,* The Construction of Rigid Supramolecular Polymers in Water through the Self-assembly of Rod-like Monomers and Cucurbit[8]uril, Chem. Commun. 2014, 50, 7982-7985.

（2）Ying Zhang, Tian-You Zhou, Kang-Da Zhang, Jin-Ling Dai, Yuan-Yuan Zhu, Xin Zhao,* Encapsulation Enhanced Dimerization of a Series of 4-Aryl-N-methylpyridinium Derivatives in Water: New Building Blocks for Self-Assembly in Aqueous Media, Chem. Asian J. 2014, 9, 1530-1534.

（3）Feng Lin,Tian-You Zhou,Tian-Guang Zhan, Xin Zhao,* Wholly-Rigid Rod-Rod Amphiphiles: Synthesis, Crystal Structures, and Self-Assembling Behavior in Water, Tetrahedron2014, 70, 2251-2256.

（4）Bo Nie, Tian-Guang Zhan, Tian-You Zhou,Ze-Yun Xiao,Guo-Fang Jiang,* Xin Zhao,* Self-Assembly of Chiral Propeller-Like Supermolecules with Unusual “Sergeants-and-Soldiers” and “Majority-Rule” Effects, Chem. Asian J. 2014, 9, 754-758.

（5）Chun-Fang Wu, Zhi-Ming Li, Xiao-Na Xu, Zhi-Xiong Zhao, Xin Zhao,* Jin-Tao Liu, Ren-Xiao Wang, Zhan-Ting Li,* Folding-Induced Folding: The Assembly of Aromatic Amide and 1,2,3-Triazole Hybrid Helices, Chem. Eur. J.2014, 20, 1418-1426.

（6）Cen Zhou, Jia Tian, Ji-Liang Wang, Dan-Wei Zhang, Xin Zhao,* Yi Liu,* Zhan-Ting Li,* A Three-dimensional Cross-Linking Supramolecular Polymer Stabilized by the Cooperative Dimerization of Viologen Radical Cation, Polym. Chem. 2014, 5, 341-345.

（7）Kang-Da Zhang, Jia Tian, David Hanifi, Yuebiao Zhang,Andrew Chi-Hau Sue, Tian-You Zhou, Lei Zhang, Xin Zhao,* Yi Liu,*Zhan-Ting Li*, Toward a Single-Layer Two-Dimensional Honeycomb Supramolecular Organic Framework in Water, J. Am. Chem. Soc. 2013, 135, 17913-17918. (Cover art)

（8）Tian-You Zhou, Feng Lin, Zhan-Ting Li, Xin Zhao,* Single-Step Solution-Phase Synthesis of Free-Standing Two-Dimensional Polymers and their Evolution into Hollow Spheres, Macromolecules, 2013, 46, 7745-7752.

（9）Zhu-Ming Shi, Chun-Fang Wu, Tian-You Zhou, Dan-Wei Zhang, Xin Zhao,* Zhan-Ting Li,* Foldamer-Based Chiral Supramolecular Alternate Block Copolymers Tuned by Ion-Pair Binding, Chem. Commun. 2013, 49, 2673-2675.

（10）Kang-Da Zhang, Tian-You Zou, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Redox-Responsive Reverse Vesicles Self-Assembled by Pseudo[2]rotaxanes for Tunable Dye-Release, Langmuir 2012, 28, 14839-14844.

（11）Li-Yan You, Shi-Gui Chen, Xin Zhao,* Yi Liu, Wen-Xian Lan, Ying Zhang, Hao-jie Lu, Chun-Yang Cao，Zhan-Ting Li,* C-H×××O Hydrogen Bonding Induced Triazole Foldamers: Efficient Halogen Bonding Receptors for Organohalogens, Angew. Chem. Int. Ed. 2012, 51, 1657-1661.

（12）Chun-Fang Wu, Xin Zhao,* Wen-Xian Lan, Chunyang Cao, Jin-Tao Liu, Xi-Kui Jiang, Zhang-Ting Li,* A 1,4-Diphenyl-1,2,3-Triazole-Based b-Turn Mimic Constructed by Click Chemistry, J. Org. Chem. 2012, 77, 4261-4270.

（13）Liu-Gang Wang, Tian-Guang Zhan, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* p-Phenyleneethynylene-Based Comb-Like Oligomers: the Synthesis and Self-Assembling Property, Tetrahedron 2012, 68, 5303-5310.

（14）Zhu-Ming Shi, Shi-Gui Chen, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Meta-Substituted Benzamide Oligomers that Complex Mono-, Di- and Tricarboxylates: Folding-Induced Selectivity and Chirality, Org. Biomol. Chem.2011, 9, 8122-8129.

（15）Kang-Da Zhang, Xin Zhao,* Gui-Tao Wang, Yi Liu,* Hao-Jie Lu,* Xi-Kui Jiang, Zhan-Ting Li,* Foldamer-Tuned Switching Kinetics and Metastability of [2]Rotaxanes, Angew. Chem. Int. Ed. 2011, 50, 9866-9870.

（16）Shi-Gui Chen, Yue Yu, Xin Zhao,* Yuguo Ma,* Xi-Kui Jiang, Zhan-Ting Li,* Highly Stable Chiral (A)₆-B Supramolecular Copolymers: A Multivalency-Based Self-Assembling Process, J. Am. Chem. Soc. 2011, 133, 11124-11127.

（17）Ze-Yun Xiao, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Tunable Coordinative Assembly of a Disc-Like Molecule and Metal Ions: From Mirospheres to Microtubes and Microrods,Chem. Mater. 2011, 23, 1505-1511.

（18）Yun-Xiang Xu, Tian-Guang Zhan, Xin Zhao,* Qiang Fan, Xi-Kui Jiang, Zhan-Ting Li,* Oligo(quinoxalineethynylene)s: Synthesis, Properties, and Ag-Mediated Complanation, Chem. Commun. 2011, 47, 1524-1526.

（19）Lu Wang, Gui-Tao Wang, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Hydrogen Bonding-Directed Quantitative Self-Assembly of Cyclotriveratrylene Capsules and their Encapsulation of C₆₀ and C₇₀, J. Org. Chem. 2011, 76, 3531-3535.

（20）Ze-Yun Xiao, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Construction of Microbelts through the Co-Assembly of a Disc-Like Molecule and Primary Alkyl Ammoniums: A Noncovalent Strategy to Mimic Covalently Bonded p-Core-Alkyl Chain Structure, Langmuir 2010, 26, 13048-13051.

（21）Kang-Da Zhang, Gui-Tao Wang, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Vesicle Self-Assembly by Tetrathiafulvalene Derivatives in Both Polar and Nonpolar Solvents and Pseudo-Rotaxane Mediated Vesicles-to-Microtubes Transformation, Langmuir 2010, 26, 6878-6882.

（22）Yun-Xiang Xu, Gui-Tao Wang, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Controllable Self-Assemblies of Micro/Nano-Tubes and Vesicles from Arylamides and their Applications as Templates to Fabricate Pt Micro/Nano-Tubes and Hollow Pt Nanospheres, Soft Matter 2010, 6, 1246-1252.

（23）Xin Zhao, Zhan-Ting Li,* Hydrogen Bonded Aryl Amide and Hydrazide Oligomers: New Generation of Preorganized Soft Frameworks, Chem. Commun. 2010, 46, 1601-1616.

（24）Yu-Xiang Xu, Gui-Tao Wang, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Folding of Aromatic Amide-Based Oligomers Induced by Benzene1,3,5-tricarboxylate Anion in DMSO, J. Org. Chem. 2009, 74, 7267-7273.

（25）Yu-Xiang Xu, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Organic Nanotubes Assembled from Isophthalamides and their Application as Templates to Fabricate Pt Nanotubes, Chem. Commun. 2009, 4212-4214.

（26）Ze-Yun Xiao, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Self-Assembly of Porphyrin-Azulene-Porphyrin and Porphyrin-Azulene Conjugates, Org. Biomol. Chem.2009, 7, 2540-2547.

（27）Yun-Xiang Xu, Gui-Tao Wang, Xin Zhao,* Xi-Kui Jiang, Zhan-Ting Li,* Self-Assembly of Vesicles from Amphiphilic Aromatic Amide-Based Oligomers. Langmuir, 2009, 25, 2684-2688.

（28）W. von E. Doering,* Xin Zhao, Steric Control in the Thermal Rearrangement of a Bicyclo[3.1.0]hex-2-ene Substituted at a Radical-Non-Stabilizing Position, J. Am. Chem. Soc. 2008, 130, 6430-6437.

（29）W. von E. Doering,* Xin Zhao, Effect on Kinetics by Deuterium in the 1,5-Hydrogen Shift of a Cisoid-Locked 1,3(Z)-Pentadiene, 2-Methyl-10-methylenebicyclo[4.4.0]dec-1-ene. Evidence for Tunneling? J. Am. Chem. Soc. 2006, 128, 9080-9085.

（30）W. von E. Doering,* E. J. Keliher, Xin Zhao, Perturbation by Phenyl on the 1,5-Hydrogen Shift in 1,3(Z)-Pentadiene. Another Chameleonic Transition Region? J. Am. Chem. Soc. 2004, 126, 14206-14216.

（31）Xin Zhao, Xiao-Zhong Wang, Xi-Kui Jiang, Ying-Qi Chen, Zhan-Ting Li,* Guang-Ju Chen.* Hydrazide-Based Quadruply Hydrogen-Bonded Heterodimers. Structure, Assembling Selectivity, and Supramolecular Substitution, J. Am. Chem. Soc. 2003, 125, 15128-15139. ^[2]