趙冰

2005-2008年就讀於中國農業大學生命科學試驗班並獲得學士學位。

2008-2013年就讀於清華大學生命科學學院並獲得博士學位。

2013-2015年於清華-北大生命科學聯合中心進行博士後研究。

2015-2017於美國辛辛那提兒童醫院醫學中心從事博士後研究。

2017年起任復旦大學生命科學學院青年研究員、研究員，博士生導師。

利用小鼠遺傳、類器官模型，研究關鍵細胞信號與染色質重塑交互決定成體幹細胞命運的功能機制，並發展類器官構建新策略。

國家優秀青年基金（2020）

“東方學者”特聘教授（2019）

上海市青年拔尖人才（2018）

上海市青年科技啓明星（A類）（2018）

生命科學學院院長獎（2018）

AMGEN Postdoctoral Award（2015）

北京市優秀博士畢業生（2013）

1. Sun S, Jiang N, Jiang Y, He Q, He H, Wang X, Yang L, Li R, Liu F, Lin X* and Zhao B*. (2020) Chromatin remodeler Znhit1 preserves hematopoietic stem cell quiescence by determining the accessibility of distal enhancers. Leukemia, doi: 10.1038/s41375-020-0988-5. (* co-corresponding author)

2. Zhao B*, Ni C, Gao R, Wang Y, Yang L, Wei J, Lv T, Liang J, Zhang Q, Xu W, Xie Y, Wang X, Yuan Z, Liang J*, Zhang R* and Lin X*. (2020) Recapitulation of SARS-CoV-2 infection and chola ^[2]  ngiocyte damage with human liver ductal organoids. Protein & Cell, doi: 10.1007/s13238-020-00718-6

3. Wang X, Ni C, Jiang N, Wei J, Liang J, Zhao B* and Lin X*. (2020) Generation of liver bipotential organoids with a small-molecule cocktail. Journal of Molecular Cell Biology, mjaa010.

4. Wei J, Ran G, Wang X, Jiang N, Liang J, Lin X*, Ling C* and Zhao B*. (2019) Gene manipulation in liver ductal organoids by optimized recombinant adeno-associated virus vectors. Journal of Biological Chemistry, 294(38):14096-14104.

5. Zhao B*, Chen Ying, Jiang N, Yang L, Sun S, Zhang Y, Wen Z, Ray L, Liu H, Hou G and Lin X*. (2019) Znhit1 controls intestinal stem cell maintenance by regulating H2A.Z incorporation. Nature Communications, 10:1071.

6. Qi Z, Li Y, Zhao B, Xu C, Liu Y, Li H, Zhang B, Wang X, Yang X, Xie W, Li B, Han JJ and Chen YG*. (2017) BMP restricts intestinal Lgr5+ stem cell self-renewal by directly suppressing its signature genes. Nature Communications, 8:13824.

7. Zhao B, Qi Z, Li Y, Wang C, Fu W and Chen YG*. (2015) The non-muscle-myosin-II heavy chain Myh9 mediates colitis-induced epithelium injury by restricting Lgr5+ stem cells. Nature Communications, 6:7166.

8. Lin L, Liu L, Zhao B, Xie R, Lin W, Li H, Li Y, Shi M, Chen YG, Springer TA and Chen X*. (2015) Carbon nanotube-assisted optical activation of TGF-β signalling by near-infrared light. Nature Nanotechnology, 10(5):465-71.

9. Cui HK#, Zhao B#, Li Y, Guo Y, Hu H, Liu L* and Chen YG*. (2013) Design of stapled α-helical peptides to specifically activate Wnt/β-catenin signaling. Cell Research, 23:581-584. (# co-first author)

10. Zhao B, Wang Q, Du J, Luo S, Xia J and Chen YG*. (2012) PICK1 promotes caveolin-dependent degradation of TGF-β type I receptor.Cell Research, 22:1467-1478. ^[1]