李友國

教育及工作經歷：

1984年至1988年武漢大學細胞生物學，本科。

1988年至1991年武漢大學細胞生物學，碩士。

1991年至今華中農業大學土化系，生命科學技術學院歷任講師，副教授，教授，博士生導師。

1997年至2000年華中農業大學微生物學，博士。

2001年至2002年在荷蘭瓦赫寧根大學從事訪問研究。

2002年至2005年在英國University of East Anglia從事博士後研究。

社會任職：

1、湖北省生物工程學會理事。

2、中國微生物學會農業微生物學專業委員會委員。

《微生物學》。 ^[1] 

根瘤菌共生固氮體系的分子機理與應用

利用華癸根瘤菌-紫雲英特色模式體系，研究共生雙方調控類菌體分化、固氮及衰老的互作機制

開展大豆根瘤菌固氮及菌植互作研究，為增強競爭結瘤、提高固氮效率和大豆固氮育種提供科學依據

進行大豆和紫雲英根瘤菌的遺傳改良、整合利用PGPR、微量元素、激素等，建立與我國土壤及豆科宿主匹配的複合根瘤菌製劑應用技術 ^[2] 

1. Jianyun Wang, Zaiyong Si, Fang Li, Xiaobo Xiong, Lei Lei, Fuli Xie, Dasong Chen, Yixing Li*, Youguo Li* (2015). A purple acid phosphatase plays a role in nodule formation and nitrogen fixation in Astragalus sinicus. Plant Molecular Biology, 88 (6): 515-29.

2. Lei, L., L. Chen, X. Shi, Y. Li, J. Wang, D. Chen, F. Xie and Y. Li* (2014). A nodule-specific lipid transfer protein AsE246 participates in transport of plant-synthesized lipids to symbiosome membrane and is essential for nodule organogenesis in Chinese milk vetch. Plant Physiol 164 (2): 1045-1058.

3. Shanming Wang, Baohai Hao, Jiarui Li, Jieli Peng, Fuli Xie, Xinyin Zhao, Christian Frech, Nansheng Chen*, Binguang Ma*, Youguo Li* (2014). Whole-genome sequencing of Mesorhizobium huakuii 7653R provides molecular insights into host specificity and symbiosis island dynamics. BMC Genomics, 15: 440.

4. Peng, J., B. Hao, L. Liu, S. Wang, B. Ma, Y. Yang, F. Xie and Y. Li* (2014). RNA-Seq and Microarrays Analyses Reveal Global Differential Transcriptomes of Mesorhizobium huakuii 7653R between Bacteroids and Free-Living Cells. PLoS One 9 (4): e93626.

5. Yixing Li, Lei Zhou, Youguo Li*, Dasong Chen, Xuejuan Tan, Lei Lei and Junchu Zhou* (2008). A nodule-specific plant cysteine proteinase, AsNODF32, is involved in nodule senescence and nitrogen fixation activity of the green manure legume Astragalus sinicus. New Phytologist, 180: 185-192.

6. Jiang Ke Yang, Tian Ying Yuan, Wei Tao Zhang, Jun Chu Zhou, You Guo Li* (2008). Polyphasic characterization of mung bean (Vigna radiata L.) rhizobia from different geographical regions of China. Soil Biology & Biochemistry, 40: 1681-1688.

7. Jonathan D. Todd, Rachel Rogers, You Guo Li, Margaret Wexler, Philip L. Bond, Lei Sun, Andrew R. J. Curson, Gill Malin, Michael Steinke, Andrew W. B. Johnston (2007). Structural and Regulatory Genes Required to Make the Gas Dimethyl Sulfide in Bacteria. Science, Vol. 315: 666-669.

8. Y. Li, M. Wexler, D. J. Richardson, P. L. Bond and A. W. B. Johnston (2005). Screening a Wide Host-range, Waste-water Metagenomic Library in Tryptophan Auxotrophs of Rhizobium leguminosarum and of Escherichia coli Reveals Different Classes of Cloned trp Genes. Environmental Microbiology, 7(12), 1927-1936.

9. A.W.B.Johnston, Youguo Li and Lesley Ogilvie (2005). Metagenomic Marine Nitrogen Fixation - Feast or Famine? Trends in Microbiology, 13(9): 416-420. ^[2]