曾燕

病理生理學、內科護理學、人體工程學、公共衞生英語

1. 阿爾茨海默病（Alzheimer’s disease, AD）（俗稱老年性痴呆）的發病機制、流行病學、和早期干預。

2. 脆性X綜合徵(Fragile X Syndrome, FXS)的發病機制和早期干預。

1.國家自然科學基金； 2.武漢市科技攻關計劃。

1.Tian Mi, Zeng Yan*, Hu Yilan, Yuan Xiuxue, Liu Shumin, Li Jie, Lu Pan, Sun Yao, Gao Lei, Fu Daan, Li Yi, Shi Yuwei. TrkB Agonist 7, 8-dihydroxyflavone Changes Synapse Expression of AMPA Subunits and Ameliorates Behavioral and Spine abnormalities in a Mouse Model of Fragile X Syndrome. Neuropsychopharmacology, 2014. 2.Zeng Yan*, Wang Xiaonan, Wang Qiang, Liu Shumin, Hu Xiamin, McClintock SM. Small molecules activating TrkB receptor for treating a variety of CNS disorders. CNS Neurol Disord Drug Targets. 12(7):1066-77, 2013. 3.Zeng Yan*, Chang Wei, Shu Chang, Ma Lina, Huang Yuanyuan, Wang Ruoshi, Zhang Junpeng, Zhu Changcai, McClintock SM. Decreased cognitive function in extended family members from the single late-onset-Alzheimer's-disease pedigree. J Int Neuropsychol Soc. 2013，19(7):809-19. 4.Zeng Yan*, Liu Yakun, Wu Mianyun, Liu Jun, Hu Qi. Activation of TrkB by 7, 8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging. J Alzheimers Dis. 2012，31(4):765-78. 5.Zeng Yan*, Lv Feng, Li Long, Yu Hui, Dong Min, Fu Qinghai. 7, 8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. J Neurochem. 2012，122(4):800-11. 6.Zeng Yan, Tan Miao, Kohyama J, Sneddon M, Watson JB, Sun YE, Xie CW. Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. J Neurosci. 2011，31(49):17800-10.

2020年12月，榮獲“致公黨抗擊新冠肺炎疫情先進個人”榮譽稱號。 ^[2]