黃耀東

黃耀東：天津大學化工學院製藥工程系副教授

研究方向:

功能材料合成 不對稱催化 藥物合成

講授課程:

本科生課程: 《藥物合成反應》

研究生課程: 《藥物分子構型的光譜解析》

《現代製藥工藝學》 ^[1] 

學術兼職:

中國工程院院刊 Frontiers of Chemical Science and Engineering 主編助理，編輯部副主任

Tetrahedron, Tetrahedron Letters,Current Organic Chemistry,Letters in Drug Design & Discovery, Journal of Molecular Structure, Chemistry Letter, Chinese Chemical Letters, 化學工業與工程等期刊的審稿專家。

美國化學工程師學會 (AIChE) 會員

論著專利:

參與編寫的著作：《藥物合成反應基礎》，化學工業出版社，2012年8月

發表的論文：

1. Hong-Bo Cheng, Ziyan Li, Yao-Dong Huang, Lei Liu, Hai-Chen Wu*. Pillararene-based aggregation-induced-emission-active supramolecular system for simultaneous detection and removal of mercury(II) in water. ACS Applied Materials & Interfaces, 2017, 9: 11889-11894. SCI: 000398764100064

2. 王路遠, 劉樹雪, 李慧敏, 黃耀東. 吡嗪二羧酸⁃三聚氰胺雙組分水凝膠的製備及性能.高等學校化學學報, 2017, 38(5): 806-813. SCI: 000401966400016

3. Yaodong Huang*, Huimin Li, Ziyan Li, Yan Zhang, Wenwen Cao, Luyuan Wang, and Shuxue Liu. Unusual C−I···O halogen bonding in triazole derivatives: gelation solvents at two extremes of polarity and formation of superorganogels. Langmuir, 2017, 33(1): 311-321. SCI: 000391898100038

4. Ziyan Li, Yaodong Huang*, Dongli Fan, Huimin Li, Shuxue Liu, Luyuan Wang. Synthesis and properties of novel organogelators functionalized with 5-iodo-1,2,3-triazole and azobenzene groups. Frontiers of Chemical Science and Engineering, 2016, 10(4): 552-561. EI: 20164603021657　SCI: 000391822300012

5. 張梅傑，曹雯雯，李紫煙，黃耀東. 長鏈烷氧基芳香醇凝膠因子的合成及性能. 精細化工, 2016, 33(6): 601-607. EI: 20162502525525

6. Yaodong Huang*, Yuqin Yuan, Wei Tu, Yan Zhang, Meijie Zhang, Hongmei Qu. Preparation of efficient organogelators based on pyrazine-2,5-dicarboxylic acid showing room temperature mesophase. Tetrahedron, 2015, 71: 3221-3230. SCI: 000355031000006

7. Yaodong Huang*, Yan Zhang, Yuqin Yuan, Wenwen Cao. Organogelators based on iodo 1,2,3-triazole functionalized with coumarin: properties and gelator-solvent interaction. Tetrahedron, 2015, 71: 2124-2133. SCI: 000351654600009

8. Hong-Bo Cheng, Yao-Dong Huang, Lina Zhao, Xu Li, Hai-Chen Wu. Prominent Bathochromic Shift Effect of Indole-Containing Diarylethene Derivatives. Organic & Biomolecular Chemistry, 2015, 13: 3470-3475. EI: 20151100626010 SCI: 000351062700038

9. Yan Zhai, Wei Chai, Wenwen Cao, Zipei Sun, Yaodong Huang*. Organogelators based on p-alkoxylbenzamide and their self-assembling properties. Frontiers of Chemical Science and Engineering, 2015, 9(4): 488-493. SCI: 000365759300008

10. 樊冬麗,翟巖,張妍,塗偉,黃耀東*.光響應偶氮苯類小分子凝膠因子的合成及性能. 高等學校化學學報, 2014, 35(11): 2447-2454. SCI: 000345540800027

11. Yao-Dong Huang*, Wei Tu, Yu-Qin Yuan, Dong-Li Fan. Novel organogelators based on pyrazine-2,5-dicarboxylic acid derivatives and their mesomorphic behaviors. Tetrahedron, 2014, 70: 1274-1282. SCI: 000330920500021

12. Zipei Sun, Xuelin Dong, Yan Zhai, Ziyan Li,Yaodong Huang*. 2,5-Dialkoxylphenyl-1,3,4-oxadiazoles as efficient organogelators and their self-assembling property. Frontiers of Chemical Science and Engineering, 2014, 8(2): 219-224. SCI: 000354903900012

13. Lili Zhang, Ming Liu, Shijun Ma, Yaodong Huang*, Yongmei Wang*. Synthesis of C₁-symmetric primary-secondary diamines and their application in the enantioselective Henry reaction. Frontiers of Chemical Science and Engineering, 2013, 7(4): 408-414. SCI: 000209386000004

14. Yao-Dong Huang*, Xue-Lin Dong, Li-Li Zhang, Wei Chai, Ji-Young Chang. Structure–property correlation of benzoyl thiourea derivatives as organogelators. Journal of Molecular Structure, 2013, 1031: 43-48. SCI: 000312686000007

15. Lili Zhang, Hao Wu, Zhongyue Yang, Xiufang Xu, Haitao Zhao, Yaodong Huang*, Yongmei Wang*. Synthesis and computation of diastereomeric phenanthrolineequinine ligands and their application in asymmetric Henry reaction. Tetrahedron, 2013, 69: 10644-10652. SCI: 000328446000015

16. Ming Liu, Shijun Ma, Zhiqing Tian, Hao Wu, Lulu Wu, Xiufang Xu, Yaodong Huang*, Yongmei Wang*. Modular bipyridine ligangs coupled with Cinchona alkaloids for Cu(II)-catalyzed asymmetric Henry reactions. Tetrahedron: Asymmetry, 2013, 24: 736-743. SCI: 000321412800007

17. Shijun Ma, Lulu Wu, Ming Liu, Xiufang Xu, Yaodong Huang*, Yongmei Wang*. Highly enantioselective aza-Michael addition reactionsof 4-nitrophthalimide with α,β-unsaturated ketones. RCS Advances, 2013, DOI: 10.1039/c3ra41179f. SCI: 000321203900019

18. Shijun Ma, Ming Liu, Yaodong Huang*, Yongmei Wang*. Enantioselective organocatalytic aza-Michael additions of phthalimide derivatives to α,β-unsaturated aldehydes.Chinese Journal of Chemistry, 2013, 31: 726-730. SCI: 000320392400005

19. Shijun Ma, Lulu Wu, Ming Liu, Yaodong Huang*, Yongmei Wang*. Asymmetric aza-Michael additions of 4-nitrophthalimide to nitroalkenes and preliminary study of the products for herbicidal activities. Tetrahedron, 2013, 69: 2613-2618. SCI: 000315610400015

20. Hao Wu, Lili Zhang, Zhiqing Tian, Yaodong Huang*, Yongmei Wang*. Highly efficient enantioselective construction of bispirooxindoles containing three stereocenters through an organocatalytic cascade Michael-cyclization reaction. Chemistry—A European Journal, 2013, 19: 1747-1753. SCI: 000313787700032

21. 董雪林，黃耀東. 2,5-二(對烷氧基苯基)-1,3,4-噁二唑合成研究. 化學工業與工程, 2013, 30(2): 36-39

22. 王書成，柴偉，黃耀東. 芳香雙硫脲類化合物的合成及其凝膠性能研究. 化學工業與工程, 2013, 30(3): 17-23

23. 董營，肖穎，黃耀東，白鵬. 萃取精餾分離碳酸二甲酯-乙醇二元共沸物. 化工進展, 2013, 32(4): 750-756

24. Hao Wu, Zhiqing Tian, Lili Zhang, Yaodong Huang*, Yongmei Wang*. Organocatalytic enantioselective aza-michael addition of purine bases to α,β-unsaturated ketones. Advance Synthesis & Catalysis. 2012, 354: 2977-2984.SCI:000310879100014

25. 柴偉，李月傑，解卓峯，黃耀東*，Chang Ji-Young. β-羰基酰胺類化合物的配位研究及晶體結構. 高等學校化學學報, 2012, 33(8): 1738-1744. SCI: 000308266900020

26. Byung Mun Jung, Yao Dong Huang, Ji Young Chang. Preparation of discotic metallomesogens based on phenacylpridines showing room temperature columnar phases. Liquid Crystals, 2010, 37(1): 85-92. SCI: 000273555000010

27. Yu Li Zhi, Xu Ke Xin, Meng Ji Ben, Huang Yao Dong*. Addition reaction of bis(diphenylphosphinyl) butadiyne with methylcyclopentadiene. Chinese Journal of Structure Chemistry, 2007, 26(8): 149-152. SCI: 000249261600013

28. 曹萌萌,李玲,羅振福,黃耀東.2’-脱氧-5-氟尿苷的合成工藝改進.天津藥學, 2007, 19(4): 82-84

29. 李傑,黃耀東,曹鳳習. NiB 非晶態合金催化劑用於可可鹼加氫還原反應中的研究. 河北化工, 2007, 30(8): 42-43

30. 馬彥琴,楊相平,張桂森,黃耀東. 培美曲塞二鈉的合成.中國新藥雜誌，2007, 16(2): 134-137

31. 賴鑫芬，黃耀東，宗矩. 新型心力衰竭治療藥物研究進展.世界臨牀藥物, 2007, 28(3): 157-162

32. Yong-Chul Jeong, Yao Dong Huang, Soojin Choi, Kwang-Hyun Ahn. Synthesis of sterically controlled chiral β-amino alcohols and their application to the catalytic asymmetric sulfoxidation of sulfides. Tetrahedron: Asymmetry, 2005, 16: 3497-3501.SCI: 000233784100009

33. 李志紅, 黃耀東. 磷酸川芎嗪片工藝及溶出度研究. 廣東藥學, 2005, 15(5): 15-17

34. Yong-Chul Jeong, Soojin Choi, Yao Dong Hwang, Kwang-Hyun Ahn. Enantioselective oxidation of sulfides with hydrogen peroxide catalyzed by vanadium complex of sterically hindered chiral Schiff bases. Tetrahedron Letters, 2004, 45: 9249-9252.SCI: 000225382700022

35. Yao-Dong Huang, Ji-Ben Meng, Hai-Tao Yu, Teruo Matsuura, Yong-Mei Wang. The crystal structure of a novel host 9,9,10,10-tetrahydro-9,10,9,10-biethenobianthracene–11,11-bis-(diphenylphosphine oxide)-12,12-diyl. Journal of Molecular Structure, 2002, 604: 119-123.SCI: 000173859500003

36. Yao-Dong Huang, Hai-Tao Yu, Ji-Ben Meng, Teruo Matsuura, Yong-Mei Wang. Synthesis and crystal structure of 9,10-dihydro-9,10-etheno-1,8-dichloro-11- diphenylphosphinyl-12- (diphenylphosphinylethynyl)anthracene. Journal of Molecular Structure, 2002, 610: 247-252.SCI: 000175735600030

37. Yao-Dong Huang, Hai-Tao Yu, Ji-Ben Meng, Yong-Mei Wang. Synthesis and crystal structure of spiro[bicyclo[2.2.1]hepta-2,5-diene-7,1ˊ-cyclopropane]. Chinese Journal of Structure Chemistry, 2002, 21(2): 149-152. SCI: 000174595000007

合作交流:

2014年11月，美國亞特蘭大，2014 AIChE Annual Meeting;

2013年7月，西安，Frontier in Chemical Engineering: The Fifth Global Chinese Chemical Engineers Symposium；

本課題組與Seoul National University, Kyung Hee University, 南開大學，中國科學院高能物理研究所的研究組有合作交流。

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