馮凡

姓名：馮凡

學位：博士

職稱：講師

研究方向:基於組學技術開發降血糖活性或抗腫瘤活性的小分子化合物及其調控機制

二、承擔項目

主持獲批2021年度宿州市科技攻關項目1項，主持完成2019年度安徽省教育廳自然科學重點研究項目和宿州學院2019年度博士科研啓動基金項目各1項，近年來參加了國家自然科學基金項目2項，已發表SCI論文15餘篇。

三、代表性學術論文

1.Feng Fan, Hu Ping, Tao Xingkui*. Mulberry leaf polysaccharide extracted by response surface methodolog suppresses the proliferation, invasion and migration of MCF-7 breast cancer cells[J]. Food Science and Technology, 2022, 42: e05122.

2.Feng Fan, Zhang Dongjing, Han Fangkai, Zhang Xingtao, Duan Tengfei, Zhang Xiuwen*. Downregulation of GATS gene inhibits proliferation, clonogenicity and migration in triple negative breast cancer cells MDA-MB-231 by cell autophagy[J]. Cancer Biomarkers, 2019, 26(3): 261-269.

3.Fan Feng, Xiaolan Zhu, Chunyan Wang, Liang Chen, Weiping Cao, Yueqin Liu, Qi Chen, Wenlin Xu*. Downregulation of hypermethylated in cance-1 by miR-4532 promotes adriamycin resistance in breast cancer cells[J]. Cancer Cell International, 2018, 18: 127.

4.Qi Ge, Shu Zhang, Liang Chen, Min Tang, Lanlan Liu, Mengna Kang, Lu Gao, Shangshang Ma, Yanhua Yang, Peng Lv, Ming Kong, Qin Yao,Fan Feng*and Keping Chen*. Mulberry leaf regulates differentially expressed genes in diabetic mice liver based on RNA-Seq analysis[J]. Frontiers in Physiology, 2018, 9: 1051.

5.Ge Q, Chen L, Tang M, Zhang S, Liu L, Gao L, Ma S, Kong M, Yao Q,Feng F*, Chen K*. Analysis of mulberry leaf components in the treatment of diabetes using network pharmacology[J]. Eur J Pharmacol, 2018, 833: 50-62.

6.Feng Fan, Zhang Xiuwen, Cao Weiping, Liu Yueqin, Chen Qi, Shen Huiling, Zhu Xiaolan, Xu Wenlin*. The CD44 variant induces K562 cell acquired with resistance to adriamycin via NF-κB/Snail/Bcl-2 pathway[J]. Medical Hypotheses, 2018, 121: 142-148. ^[1]