陳桂林

2019.09 -至今 中國科學院武漢植物園，副研究員

2017.07-2019.08 中國科學院武漢植物園，助理研究員

2014.09-2017.06中國科學院大學（中國科學院武漢植物園），植物學專業，理學博士

2006.09-2013.06 湖北中醫藥大學，製藥工程專業學士/藥物化學專業碩士

天然藥物化學、分析化學

2018年，中國科學院武漢植物園“明星員工”榮譽

2018年，中國科學院武漢植物園優秀兼職安全員稱號

2017年，中國科學院大學“三好學生”榮譽

1.主持國家自然科學基金青年基金項目：基於藥物蛋白質組學與多靶點超濾篩選研究匙羹藤干預餐後高血糖的作用機制與活性物質基礎，81903791，20萬元，2020.01-2022.12

2.主持湖北省自然科學基金青年基金項目：基於多靶點超濾質譜研究中藥匙羹藤降糖的活性物質基礎與作用機制，2019CFB254，5萬，2019.09-2021.09

3.主持中國科學院青年創新促進會項目：飛龍掌血抗腫瘤活性成分的多靶點篩選與作用機制研究，2020337，80萬元，2020.01-2023.12

1. Chen GL, Xu YB, Wu JL, Li N, Guo MQ. Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents. Food Chemistry, 2020, 333, 127478.

2. Chen GL, Mutie FM, Xu YB, Saleri FD, Hu GW, Guo MQ. Antioxidant, anti-inflammatory activities and polyphenol profile of Rhamnus prinoides. Pharmaceuticals, 2020, 13, 55.

3. Chen GL, Seukep AJ, Guo MQ. Recent advances in molecular docking for the research and discovery of potential marine drugs. Marine Drugs, 2020, 18, 545.

4. Chen GL, Fan MX, Wu JL, Li N, Guo MQ. Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule. Food Chmistry, 2019, 277, 706-712.

5. Chen GL, Zhu MZ, Guo MQ. Research advances in traditional and modern use of Nelumbo nucifera: Phytochemicals, health promoting activities and beyond. Critical Reviews in Food Science and Nutrition, 2019, 59, 189.

6. Chen GL, Fan MX, Liu Y, Sun BQ, Liu MX, Wu JL, Li N, Guo MQ. Advances in MS based strategies for probing ligand-target interactions: Focus on soft ionization mass spectrometric techniques. Frontiers in Chemistry, 2019, 7, 703.

7. Chen GL, Wu JL, Li N, Guo MQ. Screening for anti-proliferative and anti-inflammatory components from Rhamnus davurica Pall. using bio-affinity ultrafiltration with multiple drug targets. Analytical and Bioanalytical Chemistry, 2018, 410, 3587-3595.

8. Chen GL, Huang BX, Guo MQ. Current advances in screening for bioactive components from medicinal plants by affinity ultrafiltration mass spectrometry. Phytochemical Analysis, 2018, 29, 375-386.

9. Chen GL, Guo MQ. Screening for topoisomerases I inhibitors from herbal medicines combining bioaffinity ultrafiltration and LC-MS. Chinese Medicine, 2018, 13, 19-20.

10. Chen GL, Guo MQ. Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets. International Journal of Mass Spectrometry 2018, 434, 87-92.

11. Chen GL, Guo MQ. Screening for natural inhibitors of topoisomerases I from Rhamnus davurica by affinity ultrafiltration and high-performance liquid chromatography-mass spectrometry. Frontiers in Plant Science, 2017, 8, 1521.

12. Chen GL, Guo MQ. Rapid screening for α-glucosidase inhibitors from Gymnema sylvestre by affinity ultrafiltration-HPLC-MS. Frontiers in Pharmacology, 2017, 8, 228.

13. Chen GL, Li X, Saleri F, Guo MQ. Analysis of flavonoids in Rhamnus davurica and its antiproliferative activities. Molecules, 2016,21,1536.

14. Chen GL, Tian YQ, Guo MQ. Screening for inhibitors of topoisomerase I from Lycoris radiata by combining ultrafiltration with liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry 2016, 30, 95-99.

15. Xu YB, Chen GL, Guo MQ. Correlations between phytochemical fingerprints of Moringa oleifera leaf extracts and their antioxidant activities revealed by chemometrics analysis. Phytochemical Analysis, 2020.

16. Fan MX, Chen GL, Zhang YL, Nahar F, Sarker SD, Hu GW, Guo MQ. Antioxidant and anti-proliferative properties of Hagenia abyssinica roots and their potentially active components. Antioxidants, 2020, 9, 143.

17. Fan MX, Chen GL, Sun BQ, Wu JL, Li N, Sarker SD, Nahar L, Guo MQ. Screening for natural inhibitors of human topoisomerases from medicinal plants with bio-affinity ultrafiltration and LC–MS. Phytochemistry Reviews, 2020,19,1231-1261.

18. Ding J, Chen GL, Chen GF, Guo MQ. One-pot synthesis of epirubicin-capped silver nanoparticles and their anticancer activity against Hep G2 cells. Pharmaceutics, 2019,11,123.

19. Xu YB, Chen GL, Guo MQ. Antioxidant and anti-inflammatory activities of the crude extracts of Moringa oleifera from kenya and their correlations with flavonoids. Antioxidants, 2019, 8, 296.

20. Zhu MZ, Chen GL, Wu JL, Li N, Liu ZH, Guo MQ. Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants. Phytochemical Analysis, 2018, 29, 365-374.

21. 羅舒予, 陳桂林, 張永麗, 郭明全. 卡塔夫提取物抗菌活性部位篩選及其主要活性成分. 天然產物研究與開發, 2020, 32.

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