鄭玉新

現任國家自然科學基金委醫學科學部專家諮詢委員會委員、國家環境與健康諮詢委員會委員、中國毒理學會監事長、中國環境誘變劑學會生物標誌物專業委員會主任委員。在IPCS/WHO危險度評價諮詢委員會、WHO納米健康工作組等國際組織任諮詢專家。目前擔任《中華預防醫學雜誌》副主編以及《科學通報》等多個國內學術期刊編委，擔任TAAP和BES兩個國際期刊的編委。

曾任中國疾病預防控制中心職業衞生與中毒控制所副所長、WHO職業衞生合作中心（北京）主任、國家職業衞生標準委員會副主任委員、中國毒理學會副理事長、中國毒理學會工業毒理專業委員會主任委員、中華預防醫學會衞生毒理學專業委員會主任委員等。

研究方向為環境有害因素對健康影響的標誌物及其轉化應用。曾主持完成的科研項目主要包括國家自然科學基金重點項目和麪上項目、973項目、國家“十一.五、”、“十二.五”科技支撐項目、衞生公益性行業科研專項重點項目以及國際合作項目等。

獲中華預防醫學獎、“十一.五”國家科技計劃執行突出貢獻獎等獎項。主編和參編書籍6部，發表論文300餘篇。培養博士和碩士研究生40餘名。 ^[1] 

第一屆國家疾病預防控制標準委員會地方病標準專業委員會顧問。 ^[2] 

1. 國家自然科學基金重大研究計劃集成項目“大氣細顆粒物健康危害的系統毒理學與系統流行病學研究 ”（91943301） 2020.1-2022.12 主要參加者

2.國家自然科學基金重大研究計劃重點支持項目“交通尾氣顆粒物致健康損害效應的關鍵組分及人羣生物標誌物研究”（91643203）2017.1-2020.12 項目負責人

3.科技部重點研發計劃“基於人羣隊列的食品污染物生物標誌物研究與應用”(2017YFC1600202) 2018.01-2021.12，項目負責人

1. Dai Y, Zhou W, Jia Q, Dong H, Niu Y, He J, Bin P, Yi J, Xiang Y, Duan H, Huang H, Sha Y, Shen M, Ye M, Huang X, Zheng Y. Utility evaluation of HLA-B*13:01 screening in preventing trichloroethylene-induced hypersensitivity syndrome in a prospective cohort study. Occup Environ Med. 2020 Mar;77(3):201-206. doi: 10.1136/oemed-2019-106171. Epub 2020 Feb 5. PMID: 32024660

2. Chen S, Li D, Wu X, Chen L, Zhang B, Tan Y, Yu D, Niu Y, Duan H, Li Q, Chen R, Aschner M, Zheng Y, Chen W. Application of cell-based biological bioassays for health risk assessment of PM2.5 exposure in three megacities, China. Environ Int. 2020 Apr 4;139:105703. doi: 10.1016/j.envint.2020.105703. Online ahead of print. PMID: 32259755

3. Cui L, Shi L, Li D, Li X, Su X, Chen L, Jiang Q, Jiang M, Luo J, Ji A, Chen C, Wang J, Tang J, Pi J, Chen R, Chen W, Zhang R, Zheng Y. Real-Ambient Particulate Matter Exposure-Induced Cardiotoxicity in C57/B6 Mice. Front Pharmacol. 2020 Mar 31;11:199. doi: 10.3389/fphar.2020.00199. eCollection 2020. PMID: 32296328

4. Cheng W, Liu Y, Tang J, Duan H, Wei X, Zhang X, Yu S, Campen MJ, Han W, Rothman N, Belinsky SA, Lan Q, Zheng Y, Leng S.Carbon content in airway macrophages and genomic instability in Chinese carbon black packers. Arch Toxicol. 2020 Mar;94(3):761-771. doi: 10.1007/s00204-020-02678-6. Epub 2020 Feb 19. PMID: 32076763

5. Li Y, Yang M, Meng T, Niu Y, Dai Y, Zhang L, Zheng X, Jalava P, Dong G, Gao W, Zheng Y. Oxidative stress induced by ultrafine carbon black particles can elicit apoptosis in vivo and vitro. Sci Total Environ. 2020 Mar 20;709:135802. doi: 10.1016/j.scitotenv.2019. 135802. Epub 2019 Dec 17. PMID: 31887498

6. Zhang J, Zhou Q, Su R, Sun Z, Zhang W, Jin X, Zheng Y. Cardiac dysfunction and metabolic remodeling due to seasonally ambient fine particles exposure. Sci Total Environ. 2020 Mar 6;721:137792. doi: 10.1016/j.scitotenv.2020.137792. Online ahead of print. PMID: 32182466

7. Chen S, Li D, Zhang H, Yu D, Chen R, Zhang B, Tan Y, Niu Y, Duan H, Mai B,Chen S, Yu J, Luan T, Chen L, Xing X, Li Q, Xiao Y, Dong G, Niu Y, Aschner M,Zhang R, Zheng Y, Chen W. The development of a cell-based model for theassessment of carcinogenic potential upon long-term PM2.5 exposure. Environ Int. 2019 Oct;131:104943. doi: 10.1016/j.envint.2019.104943. Epub 2019 Jul 8. PubMedPMID: 31295644.

8. He Z, Zhang R, Chen S, Chen L, Li H, Ye L, Li Q, Wang Z, Wang Q, Duan H, NiuY, Xiao Y, Dong G, Li D, Yu D, Zheng Y, Xing X, Chen W. FLT1 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation. Environ Pollut. 2019 Sep;252(Pt A):607-615. doi: 10.1016/j.envpol.2019.05.137. Epub 2019 May 28. PubMed PMID: 31185349.

9. Chu C, Zhou L, Xie H, Pei Z, Zhang M, Wu M, Zhang S, Wang L, Zhao C, Shi L,Zhang N, Niu Y, Zheng Y, Zhang R. Pulmonary toxicities from a 90-day chronicinhalation study with carbon black nanoparticles in rats related to thesystemical immune effects. Int J Nanomedicine. 2019 Apr 30;14:2995-3013. doi:10.2147/IJN.S198376. eCollection 2019. PubMed PMID: 31118618; PubMed CentralPMCID: PMC6503190.

10.Chen Z, Yang L, Huang Y, Spencer P, Zheng W, Zhou Y, Jiang S, Ye W, Zheng Y,Qu W. Carcinogenic risk of N-Nitrosamines in Shanghai Drinking Water: Indicationsfor the Use of Ozone Pretreatment. Environ Sci Technol. 2019 Jun18;53(12):7007-7018. doi: 10.1021/acs.est.8b07363. Epub 2019 May 24. PubMed PMID:31083987.

11.Wang G, Zheng X, Duan H, Dai Y, Niu Y, Gao J, Chang Z, Song X, Leng S, Tang J, Zheng Y. High-content analysis of particulate matters-induced oxidative stress and organelle dysfunction in vitro. Toxicol In Vitro. 2019 Sep; 59:263-274. doi:10.1016/j.tiv.2019.04.026. Epub 2019 Apr 25. PubMed PMID: 31029784.

12.Yang M, Li Y, Meng T, Zhang L, Niu Y, Dai Y, Gao W, Bloom MS, Dong G, Zheng Y. Ultrafine CB-induced small airway obstruction in CB-exposed workers and mice. Sci Total Environ. 2019 Jun 25;671:866-873. doi: 10.1016/j.scitotenv.2019.03.033.Epub 2019 Mar 16. PubMed PMID: 30947057.

13.Li D, Zhang R, Cui L, Chu C, Zhang H, Sun H, Luo J, Zhou L, Chen L, Cui J,Chen S, Mai B, Chen S, Yu J, Cai Z, Zhang J, Jiang Y, Aschner M, Chen R, Zheng Y, Chen W. Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China. Environ Pollut. 2019 May; 248:874-887. doi: 10.1016/j.envpol.2019.02.097. Epub2019 Mar 2. PubMed PMID: 30856503.

14.Chu C, Zhang H, Cui S, Han B, Zhou L, Zhang N, Su X, Niu Y, Chen W, Chen R, Zhang R, Zheng Y. Ambient PM2.5 caused depressive-like responses through Nrf2/NLRP3 signaling pathway modulating inflammation. J Hazard Mater. 2019 May5; 369:180-190. doi: 10.1016/j.jhazmat.2019.02.026. Epub 2019 Feb 10. PubMed PMID:30776601.

15.Zheng X, Wang G, Bin P, Meng T, Niu Y, Yang M, Zhang L, Duan H, Yu T, Dai Y, Zheng Y. Time-course effects of antioxidants and phase II enzymes on diesel exhaust particles-induced oxidative damage in the mouse lung. Toxicol Appl Pharmacol. 2019 Mar 1;366:25-34. doi: 10.1016/j.taap.2019.01.010. Epub 2019 JanPubMed PMID: 30641076.

16.Wei Hu, Bryan A. Bassig, Yufei Dai, Dianzhi Ren, Huawei Duan, Yong Niu, Jun Xu, Wei Fu, Kees Meliefste, Baosen Zhou, Jufang Yang, Meng Ye, Xiaowei Jia, Tao Meng, Ping Bin, Jason YY Wong, Dean H. Hosgood, Nathaniel Rothman, Roel C. Vermeulen, Debra T. Silverman, Yuxin Zheng and Qing Lan. Abstract 597: Occupational exposure to diesel engine exhaust and alternations in serum microRNAs. DOI: 10.1158/1538-7445.AM2019-597

17.Zhiyuan Chen, Lan Yang, Ziqi Li, Yu Huang, Hao Jiang, Wuren Ma, Weiwei Zheng, Yuxin Zheng, Weidong Qu. Application of biomarkers in the study of the health effects of disinfection by-products, Current Opinion in Environmental Science & Health, Volume 7,2019,Pages 108-116,ISSN 2468-5844.

18.Wang H, Duan H, Meng T, Yang M, Cui L, Bin P, Dai Y, Niu Y, Shen M, Zhang L, Zheng Y, Leng S. Local and Systemic Inflammation May Mediate Diesel Engine Exhaust-Induced Lung Function Impairment in a Chinese Occupational Cohort. Toxicol Sci.2018Apr 1;162(2): 372-382. doi: 10.1093/toxsci/kfx259.

19.Dai Y, Ren D, Bassig BA, Vermeulen R, Hu W, Niu Y, Duan H, Ye M, Meng T, Xu J, Bin P, Shen M, Yang J, Fu W, Meliefste K, Silverman D, Rothman N, Lan Q, Zheng Y. Occupational exposure to diesel engine exhaust and serum cytokine levels. Environ Mol Mutagen.2018Mar;59(2):144-150. doi: 10.1002/em.22142. Epub 2017 Oct 12.

20.Zheng J, Zheng W, Zhou Y, Jiang S, Spencer P, Ye W, Zheng Y, He G, Qu W. Heavy Exposure of Waste Collectors to Polycyclic Aromatic Hydrocarbons in a Poor Rural Area of Middle China. Environ Sci Technol.2018Aug 7;52(15):8866-8875. doi: 10.1021/acs.est.8b02024. Epub2018Jul 18.

21.Niu Y, Zhang X, Meng T, Wang H, Bin P, Shen M, Chen W, Yu S, Leng S, Zheng Y Exposure characterization and estimation of benchmark dose for cancer biomarkers in an occupational cohort of diesel engine testers. J Expo Sci Environ Epidemiol.2018Nov;28(6):579-588. doi: 10.1038/s41370-018-0061-x. Epub2018Sep 5

22.Yu P, Jiao J, Chen G, Zhou W, Zhang H, Wu H, Li Y, Gu G, Zheng Y, Yu Y, Yu S. Effect of GRM7 polymorphisms on the development of noise-induced hearing loss in Chinese Han workers: a nested case-control study. BMC Med Genet.2018Jan 5;19(1):4. doi: 10.1186/s12881-017-0515-3.

23.Wang Y, Duan H, Meng T, Shen M, Ji Q, Xing J, Wang Q, Wang T, Niu Y, Yu T, Liu Z, Jia H, Zhan Y, Chen W, Zhang Z, Su W, Dai Y, Zhang X, Zheng Y.Reduced serum club cell protein as a pulmonary damage marker for chronic fine particulate matter exposure in Chinese population. Environ Int.2018Mar; 112:207-217. doi: 10.1016/j.envint.2017.12.024. Epub 2017 Dec 22.

24.Wang G, Zheng X, Tang J, Niu Y, Dai Y, Duan H, Zheng Y. LIN28B/let-7 axis mediates pulmonary inflammatory response induced by diesel exhaust particle exposure in mice. Toxicol Lett.2018Dec 15;299:1-10. doi: 10.1016/j.toxlet.2018.08.019. Epub2018Aug29.

25.Zhang C, Quan Z, Wu Q, Jin Z, Lee JH, Li C, Zheng Y, Cui L. Association between Atmospheric Particulate Pollutants and Mortality for Cardio-Cerebrovascular Diseases in Chinese Korean Population: A Case-Crossover Study. Int J Environ Res Public Health. 2018 Dec 12;15(12). pii: E2835. doi: 10.3390/ijerph15122835. PubMed PMID: 30545115; PubMed Central PMCID: PMC6313322. ^[1]