賀光

上海交通大學研究員賀光圖片

精神疾病易感基因的研究，破解精神分裂症患者結直腸癌發生率低於正常之謎的初步研究，出生前營養不良導致精神分裂症的分子機制初探，揭示出生前營養不良導致成年後精神疾病發病風險增加的分子機制。 ^[1] 

1. Wang Y, Zhang J, Liu B, Shao L, Wei Z, Li X, Ji J, Yang F, Wang T, Liu J, Wan C, Li B, Xu Y, Feng G, He L*, He G*. Genetic polymorphisms in the SCN8A gene are associated with suicidal behavior in psychiatric disorders in the Chinese population. World J Biol Psychiatry. 2010;11(8):956-63.

2. HTR2C promoter polymorphisms are associated with risperidone efficacy in Chinese female patients.Liu BC, Zhang J, Wang L, Li XW, Wang Y, Wei ZY, Ji J, Yang FP, Wan CL, Xu YF, Feng GY, He L*, He G*. Pharmacogenomics. 2010;11(5):685-92.

3. Shi YY*, He G*, Zhang Z, Tang W, Zhang J Jr, Zhao Q, Zhang J Sr, Li XW, Xi ZR, Fang C, Zhao XZ, Feng GY, He L*. A study of rare structural variants in schizophrenia patients and normal controls from Chinese Han population. Mol Psychiatry. 2008 Oct;13(10):911-3.

4. Zhang J, Shen Y, He G*, Li X, Meng J, Guo S, Li H, Gu N, Feng G, He L*. Lack of association between three serotonin genes and suicidal behavior in Chinese psychiatric patients. Prog Neuropsychopharmacol Biol Psychiatry. 2008; 32(2): 467-71.

5. He G#, Liu X#, Qin W, Chen Q, Wang X, Yang Y, Zhou J, Xu Y, Gu N, Feng G, Sang H, Wang P, He L*. MPZL1/PZR, a novel candidate predisposing schizophrenia in Han Chinese. Mol Psychiatry. 2006; 11(8):748-51.

6. Chen Q, He G, Qin W, Chen QY, Zhao XZ, Duan SW, Liu XM, Feng GY, Xu YF, St Clair D, Li M, Wang JH, Xing YL, Shi JG, He L*. Family-based association study of synapsin II and schizophrenia. Am J Hum Genet. 2004; 75(5):873-7。

2020年1月10日，獲得國家自然科學二等獎（項目名稱“基於連鎖不平衡及長單倍型分析的精神疾病關鍵基因精細定位研究”，第四完成人）。 ^[2]