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胡凱
（南京鼓樓醫院眼科主任醫師）
鎖定
胡凱，南京鼓樓醫院眼科行政副主任，主任醫師，教授，南京大學醫學院博士生導師，中華醫學會江蘇省眼科學分會委員，中國醫師協會江蘇眼科分會基礎研究與臨牀轉化學組副組長，美國視覺與眼科學研究協會會員，擅長白內障、斜弱視、角膜眼表及視網膜疾病的診治及手術。
[1-2]
- 中文名
- 胡凱 [3]
- 國 籍
- 中國
- 畢業院校
- 哈佛大學
- 臨牀職稱
- 主任醫師
- 執業地點
- 南京鼓樓醫院
- 學位/學歷
- 博士
胡凱著作譯作
Shen W, Wang C, Jiang J, He Y, Liang Q, Hu K*. Targeted delivery of herpes simplex virus glycoprotein D to CD169+ macrophages using ganglioside liposomes alleviates herpes simplex keratitis in mice. Journal of Controlled Release.2023; 365:208-218.
[4]
Liang Q, Guo R, Tsao JR, He Y, Wang C, Jiang J, Zhang D, Chen T, Yue T, Hu K*. Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway. Int Immunopharmacol, 2023, 121:110397.
[7]
Guo R, Liang Q, He Y, Wang C, Jiang J, Chen T, Zhang D, Hu K*. Mesenchymal stromal cells-derived extracellular vesicles regulate dendritic cell functions in dry eye disease. Cells, 2023, 12: 33.
[8]
Guo R, Jiang J, Zhang Y, Liang Q, Chen T, Hu K*. Evaluation of corneal dendritic cell density and subbasal nerve density in contact lens wearers using IVCM: A systematic review and meta-analysis. Front Med (Lausanne), 2023, 10:1149803.
[9]
Yun He, Chenchen Wang, Qi Liang, Rongjie Guo, Jiaxuan Jiang, Wenhao Shen, Kai Hu*. PKHB1 Peptide Induces Antiviral Effects Through Induction of Immunogenic Cell Death in Herpes Simplex Keratitis. Frontiers in Pharmacology. 2022, 13: 1048978
[5]
Chenchen Wang, Qi Liang, Dong Sun, Yun He, Jiaxuan Jiang, Rongjie Guo, Tejsu Malla, Pedram Hamrah, Xun Liu*, Zhenping Huang*, Kai Hu*. Nectin-1 and Non-muscle Myosin Heavy Chain-ⅡB: Major Mediators of Herpes Simplex Virus-1 Entry Into Corneal Nerves. Frontiers in Microbiology. 2022, 13:830699.
[6]
Qin Q, Hu K, He Z, Chen F, Zhang W, Liu Y, Xie Z. Resolvin D1 protects against Aspergillus fumigatus keratitis in diabetes by blocking the MAPK-NF-κB pathway. Exp Eye Res, 2022, 216:108941.
[10]
Wenting Cheng, Lei Zhou, Kai Hu(共同第一), Dehua Kong, Wei Huang, Chuanjun Xu, Hao Li, Jinlong Li. Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity. ACS Sens. 2021, 6(5):1815-1822.
[11]
Arsia Jamali, Kai Hu（共同第一）,Victor G. Sendra, Tomas Blanco, Maria J. Lopez, Gustavo Ortiz, Yureeda Qazi,Lixin Zheng, Aslihan Turhan, Deshea L. Harris, Pedram Hamrah*. Characterizationof Resident Corneal Plasmacytoid Dendritic Cells and Their Pivotal Role inHerpes Simplex Keratitis. Cell Reports , 2020, 32: 108099.
Jinlong li, Kai Hu（共同第一）,Yongchen Zhang, Zhaoli Zhang, Yongfeng Yang. A Highly Sensitive ElectrochemicalSensor Based on DNA Y-Junction for Detection of Estrogen Receptor Using TargetProtein Protection Strategy. AnalyticaChimica Acta, 2019, 1086:110-115.
Jinlong Li, Kai Hu（共同第一）, ZhaoliZhang, Xiaoyan Teng, Xia Zhang. Click DNA cycling in combination with goldnanoparticles loaded with quadruplex DNA motifs enable sensitiveelectrochemical quantitation of the tuberculosis-associated biomarker CFP-10 insputum. Microchimica Acta, 2019, 186(9):662.
Jinlong Li*, Jiehua Ma, Yongchen Zhang, ZhaoliZhang, Kai Hu* . Highly sensitive electrochemical analysis oftelomerase activity based on magnetic bead separation and exonuclease III-aidedtarget recycling amplification. Bioelectrochemistry.2019, 130:107341.
Kai Hu*, Jinlong Li, Xianwen Yuan. MicroRNA-411plays a protective role in Diabetic Retinopathy through Targeted RegulatingRobo4. European Review for Medical andPharmacological Sciences. 2019, 23: 9171-9179.
Jinlong Li*, Kai Hu, Yongchen Zhang, Zhaoli Zhang, Hao Li. Highlysensitive detection of Smoothened based on the drug binding and rolling cycleamplification. Analytical andBioanalytical Chemistry. 2019, 411（22）:5721-5727.
Tejsu Malla, Jing Jiang, KaiHu*. Clinicaloutcome of combined conjunctival autograft transplantation and amniotic membranetransplantation in pterygium surgery. InternationalJournal of Ophthalmology. 2018, 11(03) :395-400.
Ru Tang, Yujia Zhai, Lili Dong, Tejsu Malla, Kai Hu*. Immunization with dendriticcell-based DNA vaccine pRSC-NLDC145.gD-IL21 protects mice against herpes simplexvirus keratitis. Immunotherapy. 2018,10(03) :189-200.
Lili Dong, Ru Tang, Yujia Zhai, Tejsu Malla,KaiHu*. DNA vaccineexpressing herpes simplex virus 1 glycoprotein C and D protects mice againstherpes simplex keratitis. InternationalJournal of Ophthalmology. 2017, 10(11)：1633-1639.
KaiHu*, Tejsu Malla, Yujia Zhai, Lili Dong, Ru Tang. Topical Administration Is APromising Inoculating Route versus Intramuscular Inoculation for The Nanoparticle-CarriedDNA Vaccine to Prevent Corneal Infections. OphthalmicResearch. 2016, 55(2):99-110.
Kai Hu, Deshea L.Harris, Takefumi Yamaguchi, Ulrich von Andrian, Pedram Hamrah*. A Dual Role forCorneal Dendritic Cells in Herpes Simplex Keratitis: Local Suppression ofCorneal Damage and Promotion of Systemic Viral Dissemination. Plos one. 2015; 10(9):e0137123.
胡凱科研成果
共發表SCI論文20餘篇，包括 Cell Reports、 Analytica Chimica Acta、Bioelectrochemistry、Vaccine、Immunotherapy等著名期刊。
胡凱擅長領域
胡凱出診時間
週二上午（南京鼓樓醫院眼科）
胡凱科研項目
國家自然科學基金（2019）
江蘇省自然科學基金（2020）
江蘇省自然科學基金（2014）
- 參考資料
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- 1. 南京鼓樓醫院眼科專家 ．南京大學醫學院附屬鼓樓醫院．2021-12-01[引用日期2021-12-26]
- 2. 南京大學醫學院博士生導師胡凱 ．南京大學醫學院．2019-07-11[引用日期2021-12-26]
- 3. 醫生執業註冊信息查詢 ．中華人民共和國國家健康委員會[引用日期2021-12-26]
- 4. Targeted delivery of herpes simplex virus glycoprotein D to CD169+ macrophages using ganglioside liposomes alleviates herpes simplex keratitis in mice ．Elsevier[引用日期2024-04-05]
- 5. PKHB1 peptide induces antiviral effects through induction of immunogenic cell death in herpes simplex keratitis ．Frontiers[引用日期2024-04-05]
- 6. Nectin-1 and Non-muscle Myosin Heavy Chain-IIB: Major Mediators of Herpes Simplex Virus-1 Entry Into Corneal Nerves ．frontiers[引用日期2024-04-05]
- 7. Salidroside alleviates oxidative stress in dry eye disease by activating autophagy through AMPK-Sirt1 pathway ．Elsevier[引用日期2024-04-05]
- 8. Mesenchymal stromal cells-derived extracellular vesicles regulate dendritic cell functions in dry eye disease ．MDPI[引用日期2024-04-05]
- 9. Evaluation of corneal dendritic cell density and subbasal nerve density in contact lens wearers using IVCM: A systematic review and meta-analysis ．Frontiers[引用日期2024-04-05]
- 10. Resolvin D1 protects against Aspergillus fumigatus keratitis in diabetes by blocking the MAPK-NF-κB pathway ．Elsevier[引用日期2024-04-05]
- 11. Enzyme-Initiated Assembly of an Extracellular-Like Two-Dimensional Nanonetwork as a Method to Detect Procancerous Activity ．ACS[引用日期2024-04-05]
- 收起
