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王秀梅

(清華大學研究員,博士生導師)

鎖定
主要從事生物材料基礎研究及生物醫用材料產品開發,主要包括材料調控幹細胞功能、誘導血管化生物材料、顱骨再生修復、神經組織再生修復材料的開發及臨牀轉化。 [1] 
(概述圖參考資料 [2] 
中文名
王秀梅
畢業院校
清華大學
學位/學歷
博士生導師
主要成就
2016清華大學“劉冰獎”(清華大學)
工作單位
清華大學

王秀梅教育背景

09/2000-01/2005: 工學博士,清華大學,材料物理與化學專業
09/1996-07/2000: 工學學士,清華大學,材料科學與工程專業 [2] 

王秀梅工作經歷

12/2013至今:研究員,博士生導師,清華大學材料學院
01/2009-12/2013: 副研究員,清華大學材料學院
01/2008-12/2008: 講師,清華大學材料科學與工程系
05/2006-01/2008: 博士後,美國麻省理工學院(MIT),生物醫學工程中心 (Center for Biomedical Engineering)
07/2005-05/2006: 博士後,美國羅切斯特大學醫學院(University of Rochester Medical Center),骨科研究中心 (Center for Musculoskeletal Research) [2] 

王秀梅學術兼職

Editor, SCI國際期刊Frontier of Materials Science
Regional Editor of Asia, 國際期刊Current Tissue Engineering
Managing Editor, 國際期刊Regenerative Biomaterials
中國生物材料學會,常務理事
中國生物材料學會神經修復材料與植入器械分會,副主任委員
中國生物材料學會青年委員會,委員
中國生物材料學會骨修復材料與器械分會,委員
中國生物材料學會再生醫學材料分會,委員
中國材料研究會青年工作委員會,常務理事
中國材料研究會外事工作委員會,委員
中國硅酸鹽學會特種陶瓷分會理事
中國機械工程學會表面工程分會生物材料表面工程專委會委員
中國醫師協會骨科醫師分會骨科技術創新與轉化工作委員會委員
中國研究型醫院學會技術創新與轉化分會骨科生物材料與內置物學組委員
全國外科植入物和矯形器械標準化技術委員會組織工程醫療器械產品分技術委員會骨再生標準工作組專家
中國抗衰老促進會交叉學科專業委員會委員 [2] 

王秀梅研究領域

生物材料、組織工程與再生醫學 [2] 

王秀梅研究概況

主要從事生物材料基礎研究及生物醫用材料產品開發,主要包括材料調控幹細胞功能、誘導血管化生物材料、顱骨再生修復、神經組織再生修復材料的開發及臨牀轉化。 [2] 

王秀梅主要貢獻

近期論文(及專利)
1.Zhang ZX, Yao SL, Xie S*, Wang XM*, Chang FY, Luo J, Wang JM, Fu J. Effect of hierarchically aligned fibrin hydrogel in regeneration of spinal cord injury demonstrated by tractography: A pilot study. Scientific Report. Scientific Reports, 2017, 7, 40017.
2.Yao SL, Liu X, Yu SK, Wang XM*, et al. Co-effects of matrix low elasticity and aligned topography on stem cell neurogenic differentiation and rapid neurite outgrowth. Nanoscale, 2016, 8, 10252-10265.
3.Xu SJ, Qiu ZY, Wu JJ, Kong XD, Weng XS, Cui FZ*, Wang XM*. Osteogenic Differentiation Gene Expression Profiling of hMSCs on Hydroxyapatite and Mineralized Collagen. Tissue Engineering Part A. 2016; 22: 170-181.
4.Guan FY, Lu JJ, Wang XM*. A novel honeycomb cell assay kit designed for evaluating horizontal cell migration in response to functionalized self-assembling peptide hydrogels. Frontiers of Materials Science. 2017, 11(1):13-21.
5.Liu FZ, Wang DW, Zhang YJ, Lv ZY, Sun XD, Li KY, Zhang B*, Wang XM*, Cui FZ. Comparison of rabbit rib defect regeneration with and without graft. Journal of Materials Science-Materials in Medicine. 2017, 28(1): 10.1007/s10856-016-5807-1.
6.Liu FZ, Lv ZY, Zhang YJ, Li KY, Wang DW, Zhang B*, Wang XM*. Comparison of Rabbit Rib Defect Regeneration Implanted Mineralized Collagen With and Without Periosteum. Journal of Biomaterials and Tissue Engineering. 2017, 7(2): 134-138.
7.Yao SL, Liu X, He J, Wang XM*, Wang Y, and Cui FZ. Ordered self-assembled monolayers terminated with different chemical functional groups direct neural stem cell linage behaviours. Biomedical Materials. 2016, 11(1): 014107.
8.Zhou JF, Cheng L, Sun XD*, Wang XM*, Jin SH, Li JX, Wu Q. Neurogenic differentiation of human umbilical cord mesenchymal stem cells on aligned electrospun polypyrrole/polylactide composite nanofibers with electrical stimulation. Frontiers of Materials Science. 2016, 10(3): 260-269.
9.Meng QY, Tao CS, Qiu ZY, Akaike T, Cui FZ, Wang XM*. A hybrid substratum for primary hepatocyte culture that enhances hepatic functionality with low serum dependency. International Journal of Nanomedicine. 2015: 10, 2313-2323.
10.Qiu ZY, Cui Y, Tao CS, Zhang ZQ, Tang PF, Mao KY, Wang XM*, Cui FZ. Mineralized Collagen: Rationale, Current Status, and Clinical Applications. Materials 2015, 8(8), 4733-4750.
11.Liu X, Pi B, Wang H, Wang XM*. Self-assembling peptide nanofiber hydrogels for central nervous system regeneration. Frontiers of Materials Science. 2015, 9(1): 1-13.
12.Lian XJ*, Mao KZ, Liu X, Wang XM, and Cui FZ. In Vivo Osteogenesis of Vancomycin Loaded Nano-Hydroxyapatite /Collagen/ Calcium Sulfate Composite for Treating Infectious Bone Defect Induced by Chronic Osteomyelitis. Journal of Nanomaterials. 2015. 261492.
13.Tao H, Wu YH, Li HF, Wang CF, Zhang Y, Li C, Wen TY, Wang XM, et al. BMP7-Based Functionalized Self-Assembling Peptides for Nucleus Pulposus Tissue Engineering. ACS Applied Materials & Interfaces. 2015. 7(31): 17076-17087.
14.Wang RH, Wang Q, Wang XM*, et al. Enhancement of nano-hydroxyapatite bonding to dentin through a collagen/calcium dual-affinitive peptide for dentinal tubule occlusion. Journal of Biomaterials Applications. 2014. 29 (2): 268-277.
15.Tao H, Zhang Y, Wang C, Zhang C, Wang XM, et al. Biological evaluation of human degenerated nucleus pulposus cells in functionalized self-assembling peptide nanofiber hydrogel scaffold. Tissue Eng Part A. 2014. 20(11-12): 1621-1631.
16.Xiao YY, Zhang WZ, Wang XM*, et al. Optimized Preparation of Thiolated Hyaluronic Acid Hydrogel with Controllable Degree of Substitution. Journal of Biomaterials and Tissue Engineering. 2014. 4(4): 281-287.
17.Meng QY, Yao SL, Wang XM*, Chen YY. RADA16: a self-assembly peptide hydrogel for the application in tissue regeneration. Journal of Biomaterials and Tissue Engineering. 2014, 4(12): 1019-1029.
18.Liu X, Wang XM*, Wang XJ, et al. Functionalized self-assembling peptide nanofiber hydrogels mimic stem cell niche to control human adipose stem cells behaviors in vitro. Acta Biomaterialia. 2013, 9, 6798-6805.
19.Yao SL, Wang XM*, Liu X, et al. Effects of ambient relative humidity and solvent properties on the electrospinning of pure hyaluronic acid nanofibers. Journal of nanoscience and nanotechnology. 2013. 13: 4752-4758.
20.Yao SL, Liu X, Wang XM*, et al. Directing neural stem cell fate with biomaterial parameters for injured brain regeneration. Progress in Natural Science: Materials International. 2013, 23(2), 103-112.
21.Liu X, He J, Zhang SM, Wang XM*, Liu HY, and Cui FZ. The fate of adipose stem cells controlled by surface chemistry. Journal of Tissue Engineering and Regen Med. 2013, 7(2): 112-117.
22.Lian XJ, Liu HY, Wang XM*, et al. Antibacterial and biocompatible properties of vancomycin-loaded nano-hydroxyapatite/collagen/poly (lactic acid) bone substitute (VCM/nHAC/PLA). Progress in Natural Science-Materials International. 2013. 23(6): 549-556.
23.Liu X, Wang XM*, Horii A, Wang XJ, Qiao L, Zhang SG, and Cui FZ. In vivo studies on angiogenic activity of two designer self-assembling peptide scaffold hydrogels in the chicken embryo chorioallantoic membrane. Nanoscale. 2012, 4 (8), 2720-2727.
24.Wang XM*, He J, Wang Y, and Cui FZ. Hyaluronic acid-based scaffold for central neural tissue engineering. Interface Focus. 2012, 2, 278-291.
25.Deng H#, Wang XM#, Du C, et al. Combined effect of ion concentration and functional groups on the surface chemistry modulated CaCO3 crystallization. CrystEngComm. 2012, 14, 6647-6653.
26.Liu ZX#, Wang XM#, Wang Q, et al. Evolution of calcium phosphate crystallization on three functional group surfaces with the same surface density. CrystEngComm. 2012, 14, 6695-6701.
27.He J, Wang XM*, Sepctor M, and Cui FZ. Scaffolds for central nervous system regeneration. Frontiers of Materials Science. 2012, 6(1): 1-25.
28.Wang Q, Wang XM*, Tian LL, Cheng ZJ, and Cui FZ. In situ remineralization of partially demineralized human dentine mediated by a biomimetic non-collagen peptide. Soft Matter. 2011, 7, 9673-9680.
29.Wang XM*, Qiao L, and Horii A. Screening of functionalized self-assembling peptide nanofiber scaffolds with angiogenic activity for endothelial cell growth. Progress in Natural Science: Materials International. 2011, 21, 111-116.
30.Chen ZJ, Wang Q, Wang XM*, Cui FZ, Ge J, Chen D, and Tian LL. Enamel Distribution, Structure and Mechanical Alterations in col1-caPPR Mice Molar. Archives of Oral Biology. 2011, 56, 1020-1026.

王秀梅所獲榮譽

2011年國家自然科學二等獎(2011-Z-108-2-03);項目名稱:生物礦化纖維的分級組裝機理研究;完成人:崔福齋、王秀梅、李恆德、蔡強、孔祥東
2011年度中華醫學科技獎三等獎 (201103069U0201);項目名稱:用組織工程技術修復中樞神經系統損傷的實驗研究;完成人:徐羣淵,崔福齋,王穎,王秀梅,田維明,魏嶽騰,任永娟,馬軍
2014年山東省科技進步一等獎;項目名稱:帶肋間神經的肋骨肌皮瓣移植修復下頜骨缺損的基礎研究與臨牀應用;完成人:張彬;朱國雄;譚穎徽;王秀梅;趙華強等。
2010年北京市科學技術獎二等獎 (2010材-2-004);項目名稱:生物礦化纖維的分級組裝機理研究;完成人:崔福齋、王秀梅、李恆德、蔡強、孔祥東
2012 年度清華大學“學術新人獎”
入選2013 年度教育部“新世紀優秀人才”支持計劃
第12屆霍英東教育基金會青年基金獎(霍英東教育基金會)
2016寶鋼優秀教師獎(寶鋼教育基金會
2016清華大學“劉冰獎”(清華大學)
參考資料