王福俤

1992年獲河北醫科大學醫學學士學位）

1995年獲同濟大學醫學院醫學碩士學位

1998年獲第二軍醫大學醫學博士學位

1998年-2002年第二軍醫大學，講師/副教授/教研室主任；2002年-2004年美國密蘇里哥倫比亞大學營養學系博士後；2004-2007年美國哈佛醫學院任講師；2008年美國佛羅里達大學研究副教授；2008年回國，中國科學院上海生命科學研究院研究員、博士生導師、首席科學家、分子營養學實驗室主任。2013年～浙江大學求是特聘教授；2013-2014年任浙江大學公共衞生學院院長；2014年~任浙江大學營養與食品安全研究所所長。2015-2018兼任鄭州大學公共衞生學院長。2021年～南華大學副校長/南華大學衡陽醫學院院長。

營養學是公共衞生體系核心學科，大力發展營養學是實現健康強國的核心戰略。鐵鋅等 金屬離子是人體必需營養素，更是營養學研究皇冠上的明珠。科學攻關金屬離子失衡機制及 防控策略關乎我國公共衞生頂層設計、全民健康體系構建和重大疾病防控決策部署。王福俤 教授30餘年聚焦金屬離子前沿研究，創新金屬離子時空穩態調控理論，創建靶向調控金屬離 子和鐵死亡精準疾病防控理論體系，推動金屬離子營養標準體系建設，創制多個靶向金屬離 子和鐵死亡新藥並提出公共衞生安全中國方案，系列重大原創突破引領國際前沿，成為營養 學、生物金屬離子和鐵死亡領域全球領導者。全球數千萬患者人羣受益，強力支撐健康中國 2030 戰略。

王福俤教授深耕營養科學，是鐵鋅金屬離子代謝、鐵死亡和鐵科學研究的全球頂尖學者。 作風優良，培養數百名青年人才，原創成果產生了巨大的社會效益和經濟效益，推動了營養 科學發展，形成了卓越國際學術影響力，為切實維護國民健康、服務科技強國戰略做出了傑 出貢獻。

國家重點人才計劃入選者（2016-）

國家傑出青年基金獲得者（2012-）

國家重點研發計劃重點專項首席科學家（2018-）

愛思唯爾中國高被引學者（2021,2022-）

全球前2%頂尖科學家（World Top 2% Scientists,斯坦福大學排名,2021-）

全球頂尖前10萬科學家（Research.com 生物學和生物化學學科,中國排名#254，D-index 56，2021，2022）

國務院政府特殊津貼專家（2014-）

科技部中青年領軍人才 （2014-）

國家百千萬人才工程“有突出貢獻中青年專家”(2015)

中國科學院百人計劃學者（2008-2012）

浙江省高層次人才特聘專家（2013-）

湖南省衞生健康高層次人才領軍人才（2022-）

中國工程院“百年科技強國發展戰略研究”專題執筆專家（2018-2019）

浙江省自然科學獎（一等獎，第一完成人，2023）

中國發明協會創業創新獎（一等獎，第一完成人，2023）

中國產學研合作創新獎（一等獎，第一完成人，2018）

浙江省科學技術進步獎（二等獎，第一完成人，2022）

教育部高等教育自然科學獎（二等獎，第一完成人，2018）

浙江大學年度十大科學進展（第一完成人，2014，2021，2022-提名獎）

中國醫學科學院血液學研究所（血液病醫院）協同創新獎（2021, 2022）

中國科學院朱李月華優秀教師獎(2011)

上海科普大講壇·科普宣講大使（上海科普大講壇管理辦公室，2012）

《科學中國人》年度人物獎（2011）

《科學中國人》封面人物（2023）

十大醫學人文院管專家（中國醫學家年會，醫師報，2022）

生物鐵國際大會BioIron（大會共同主席 2015;鐵領域世界最大最權威大會；2023大會（澳大利亞）國際學術委員會委員，Meet the Expert專題主席

中國國際生物微量元素大會（大會主席 2011,2014,2017,2019）

哈佛大學醫學歸國學者論壇（大會共同主席 2018,2019,2023）

中國抗癌協會腫瘤標誌專委會腫瘤基礎與臨牀前沿論壇暨廣州醫科大學南山講堂 （大會共同主席，廣州，2023）

第十七屆中國醫院院長年會（大會共同主席，長沙 2023）

第三屆公立醫院績效大會 （大會共同主席，長沙 2023）

生命醫學前沿·衡山論壇 （大會主席，衡陽 2023）

南華大學生命醫學·院士論壇（大會主席，衡陽 2021,2022）

創建公益宣教公眾號-營養髮現（2014-）和鐵死亡Club（2020-）等

中國生物物理學會生物微量元素分會會長（創始會長，2018-）

中國細胞生物學學會細胞死亡研究分會副會長（2020-）

中國糧油學會糧油營養分會副理事長（2020-）

鐵死亡科學家世界聯盟主席 （2020-）

國際鋅生物學學會（International Society for Zinc Biology）（會員2011-）

（Chair of the Membership Committee主席2022-，2023年度理事長有效候選人）

國際生物鐵學會（The BioIron Society鐵領域最權威學會； 董事會成員2023）

國家衞生部食品安全國家標準評審委員會委員

中國營養學會老年營養分委會委員

上海營養學會理事

上海營養學會副主任委員

上海預防醫學會營養與食品安全分委會委員

美國佛羅里達大學食品與人類營養系Courtesy Professor

中國糧油學會糧油營養分會副會長

《Research》（JCR一區）雜誌副主編

《Biophysics Reports》雜誌副主編 ^[1] 

科學影響力：近年，在金屬離子代謝、細胞鐵死亡與器官損傷領域獲得系列重大突破，引領國際學術前沿。在Nature、Nature Genetics、Nature Medicine、Nature Reviews Cardiology、Cell Research、Blood、Hepatology及PNAS等優秀期刊發表論文200餘篇，包括21篇封面論文、20篇高被引論文、6篇1‰熱點論文。論文總影響因子超過2310，論文他引近16000次，H指數64。學術期刊特邀主編4部雜誌專欄。原創成果被Nature、Cell、Nature Reviews、《新英格蘭醫學雜誌》等頂刊正面引用和評論；Circulation、Blood、Cell Research、Signal Transduction and Targeted Therapy和Protein & Cell等專業頂刊專文評述或新聞報道多次；多項科研成果被納入國際臨牀指南和權威工具教科書。

專著&基金：主編或主編譯專著5部，包括《鐵死亡》《鐵與人類健康》《鋅與人類健康》《硒:分子生物學與人體健康》(均為科學出版社)，文字合計超過430萬字。先後承擔國家傑出青年科學基金項目、國家自然科學基金重點項目（5項）及科技部國家重點研發計劃重點專項（首席科學家）。

轉化醫學研究：授權國家發明專利12項。以祛鐵靶向鐵死亡為科學理論依據，合作研發針對靶向鐵過載及鐵死亡疾患的1.1類全新祛鐵藥，已開展II期臨牀試驗；以鋅為人類必微量元素及防治多種疾病新發現為理論依據，合作研發氨基酸鋅二類新藥1項，已在2000餘家醫院應用推廣，銷售額累計約30億元；以黑豆補鐵為科學理論依據，合作研發新型功能食品已在市場試推廣。

學術研究服務：擔任Research期刊常務副主編（1區，IF11）、Biophysics Reports 期刊副主編；擔任Nature Reviews Molecular Cell Biology、Nature Reviews Endocrinology、Cell Metabolism、 Blood、Circulation、Circulation Research、European Heart Journal、Nature Communications、Cell Death and Differentiation、Journal of Clinical Investigation、 Signal Transduction and Targeted Therapy、The American Journal of Clinical Nutrition 等數十部國際著名學術期刊審稿或專評專家。

媒體關注：科研成果在 The Times、China Daily、Daily Mall、Reuters、The Sun、Yahoo News、《人民日報》《新華社》《光明日報》《文匯報》《中國科學報》《科學中國人》《生命時報》等國內外權威媒體新聞報道或專版報道數十次。

行政管理：作為南華大學副校長、南華大學衡陽醫學院院長，以全球視野、頂尖科學家的格局、傑出醫學戰略管理學家的眼光，鋭意進取，砥礪奮進。帶領南華大學衡陽醫學院及附屬醫學院奮力拼搏，連續獲得二十餘項國家級基地、獎勵與榮譽，創造了地方綜合性大學醫學教育改革的加速度，實現學科建設高質量發展，國際影響力顯著提升；建成了地方綜合性大學醫學教育改革的先鋒和示範。南華衡醫業已成為醫學科教的閃亮名片。

踐行公益科普宣教：努力踐行公眾科學教育，創立並管理多個公益宣教公眾號，包括營養髮現、鐵死亡Club、鋅醫學Club、銅生共死、錳科學Club、線粒體 Club、科學封面、解碼長壽。公眾號關注人數12餘萬人。

運用生命科學、醫學及公共衞生等學科前沿技術與平台，系統開展了四個領域的研究:(1)細胞鐵死亡與疾病診治；(2)鐵、鋅、錳、銅等金屬離子代謝分子及遺傳機制;(3)營養代謝與重大慢病防控新策略;(4)重大疾病高危死亡發生規律、易感人羣特徵及防疫策略研究。

200. Tianze Xu #, Jing Cai #, Lei Wang, Li Xu, Hongting Zhao, Fudi Wang, Esther G Meyron-Holtz, Fanis Missirlis, Tong Qiao, Kuanyu Li. Hormone replacement therapy for postmenopausal atherosclerosis is offset by late age iron deposition. eLife. 2023;12:e80494. doi: 10.7554/eLife.80494.影響因子：8.713 /Q1; 被引次數：2次

199. Danzhi Ying, Xin Shen, Shuqi Wang, Junyi Chen, Zhenying Wu, Wenteng Chen, Fudi Wang, Junxia Min*, Yongping Yu*. Discovery of 4-hydroxyl pyrazole derivatives as potent ferroptosis inhibitors. European Journal of Medicinal Chemistry. 2024; 115913. doi: 10.1016/j.ejmech.2023.115913. 影響因子：6.7 /Q1;被引次數：0次

198. Hongen Meng#, Yingying Yu#, Enjun Xie#, Qian Wu, Xiangju Yin, Bin Zhao, Junxia Min*, Fudi Wang*. Hepatic HDAC3 Regulates Systemic Iron Homeostasis and Ferroptosis via the Hippo Signaling Pathway. Research.2023;6:0281. doi: 10.34133/research.0281. 影響因子：11 /Q1;被引次數：0次

197. Fudi Wang*. Medical education of Hengyang Medical School is standing tall. Sci Sin Vitae. 王福俤. 立地頂天--南華衡醫之教育範式. 中國科學:生命科學. 2023. DOI: 10.1360/SSV-2023-0225.被引次數：0次

196. Fudi Wang*. Ferrology: a charming boundless iron-centric science. Sci Sin Vitae. 王福俤. 鐵科學（Ferrology）:充滿魅力的新型交叉學科.中國科學:生命科學.2023. https://doi.org/10.1360/SSV-2023-0192. 被引次數：0次

195. Jiebo Lin#, Guankai Zhan#, Jinfeng Liu#, Yasen Maimaitiyiming, Zhiping Deng, Baohua Li, Kunhui Su, Jiafeng Chen, Siqi Sun, Wanlin Zheng, Xianghui Yu, Feng He, Xiaodong Cheng, Lingfang Wang, Bin Shen, Ziqin Yao, Xinquan Yang, Jian Zhang, Wentao He, Hengyu Wu, Hua Naranmandura, Kao-Jung Chang, Junxia Min, Jun Ma, Mikael Björklund, Peng-Fei Xu*, Fudi Wang*, Chih-Hung Hsu*. YTHDF2-mediated regulations bifurcate BHPF-induced programmed cell deaths. National Science Review. 2023, nwad227, https://doi.org/10.1093/nsr/nwad227.影響因子：24.178 /Q1; 被引次數：0次

194.Zhaoxian Cai#, Xiaotian Wu#, Zijun Song#, Shumin Sun, Yunxing Su, Tianyi Wang, Xihao Cheng, Yingying Yu, Chao Yu, En Chen, Wenteng Chen, Yongping Yu, Andreas Linkermann, Junxia Min*, Fudi Wang*. Metformin Potentiates Nephrotoxicity by Promoting NETosis in Response to Renal Ferroptosis. Cell Discover. 2023; 9(1):104. doi: 10.1038/s41421-023-00595-3.影響因子：33.5 /Q1; 被引次數：0次

193. Shumin Sun#, Jie Shen#, Jianwei Jiang#, Fudi Wang*, Junxia Min*. Targeting ferroptosis opens new avenues for the development of novel therapeutics. Signal Transduction and Targeted Therapy. 2023; 8(1):372. doi: 10.1038/s41392-023-01606-1. 影響因子39.3/Q1; 被引次數：2次

192. Lu Jin#, Shuang Han#, Xue Lv#, Xiaofei Li#, Ziyin Zhang, Henry Kuang, Zhimin Chen, Cheng-An Lv, Wei Peng, Zhuoying Yang, Miqi Yang, Lin Mi, Tongyu Liu, Shengshan Ma, Xinyuan Qiu, Qintao Wang, Xiaowen Pan, Pengfei Shan, Yu Feng, Jin Li, Fudi Wang, Liwei Xie, Xuyun Zhao, Jun-Fen Fu*, Jiandie D Lin*, Zhuo-Xian Meng*. The muscle-enriched myokine Musclin impairs beige fat thermogenesis and systemic energy homeostasis via Tfr1/PKA signaling in male mice. Nature Communications. 2023, 14(1):4257. DOI: 10.1038/s41467-023-39710-z. PMID: 37468484. 影響因子17.694/Q1; 被引次數：1次

191. Jie Fu, Xin Zong, Mingliang Jin, Junxia Min, Fudi Wang*, Yizhen Wang*. Mechanisms and regulation of defensins in host defense. Signal Transduction and Targeted Therapy. 2023 Aug 14;8(1):300. doi: 10.1038/s41392-023-01553-x. PMID: 37574471; PMCID: PMC10423725. 影響因子38.104/Q1; 被引次數：2次

190. Shuying Shen, Jie Shen, Zhong Luo, Fudi Wang*, Junxia Mina*. Molecular Mechanisms and Clinical Implications of the Gold Drug Auranofin. Coordination Chemistry Reviews. 2023, 493: 215323. DOI: 10.1016/j.ccr.2023.215323. 影響因子：24.833 /Q1; 被引次數：3次

189. Na Li, Bowen Wu, Jifeng Wang, Yumeng Yan, Peng An, Yuezhen Li, Yuning Liu, Yanfei Hou, Xiaoqing Qing, Lili Niu, Xiang Ding, Zhensheng Xie, Mengmeng Zhang, Xiaojing Guo, Xiulan Chen, Tanxi Cai, Jianming Luo, Fudi Wang, Fuquan Yang*. Differential proteomic patterns of plasma extracellular vesicles show potential to discriminate β-thalassemia subtypes. IScience. 2023, 26(2):106048. DOI: 10.1016/j.isci.2023.106048; PMID: 36824279. 影響因子6.107/Q1; 被引次數：2次

188. Xin-yu He, Xiao Fan, Lei Qu, Xiang Wang, Li Jiang, Ling-jie Sang, Cheng-yu Shi, Siyi Lin, Jie-cheng Yang, Zuo-zhen Yang, Kai Lei, Jun-hong Li, Huai-qiang Ju, Qingfeng Yan, Jian Liu, Fudi Wang, Jianzhong Shao, Yan Xiong, Wenqi Wang*, Aifu Lin*. LncRNA modulates Hippo-YAP signaling to reprogram iron metabolism. Nature Communications. 2023, 14(1):2253. DOI:10.1038/s41467-023-37871-5; PMID: 37080959. 影響因子17.694/Q1; 被引次數：2次

187. Xuyan He#, Chaodong Ge#, Jun Xia*, Zhidan Xia, Lu Zhao, Sicong Huang, Rong Wang, Jianwei Pan, Tao Cheng, Peng-Fei Xu, Fudi Wang*, Junxia Min*. The Zinc Transporter SLC39A10 Plays an Essential Role in Embryonic Hematopoiesis. Advanced Science. 2023, 10(17):e2205345. DOI: 10.1002/advs.202205345; PMID: 37068188. 影響因子：17.521 /Q1; 被引次數：2次 【Frontispiece】【封面論文: 消防戰士-造血幹細胞鋅能源英雄ZIP10】（封面：Link：https://onlinelibrary.wiley.com/doi/10.1002/advs.202370107）

封面描述: 鋅轉運蛋白 SLC39A10 (ZIP10) 及其介導的鋅穩態對於維持胎兒造血幹/祖細胞的存活不可或缺的功能。作為造血幹細胞細胞膜上最重要的鋅輸入者，ZIP10 起着看門人的作用（就像真空將鋅運輸穿過細胞膜），以協調鋅的獲取和幹細胞的命運。

186. Xihao Cheng#, Chao Yu#, Xinquan Yang#, Fudi Wang*, Junxia Min*. A panoramic view of ferroptosis in cardiovascular disease. Kidney Diseases. 2023, 9(3):173-186. DOI: 10.1159/000530046. 影響因子：3 /Q2; 被引次數：2次 【Invited review】

185. Xue Wang#, Ye Zhou#, Junxia Min, Fudi Wang*. Zooming in and out of ferroptosis in human disease. Frontiers of Medicine. 2023, 17(2):173-206. DOI: 10.1007/s11684-023-0992-z; PMID: 37121959.【Cover Paper】 影響因子：9.927 /Q1; 被引次數：6次 【封面論文: 三英戰呂布闡釋鐵死亡與疾病博弈規律】（全文Link：https://link.springer.com/article/10.1007/s11684-023-0992-z）

184. Qin Ru #, Yusheng Li #, Wenqing Xie, Yilan Ding, Lin Chen, Guodong Xu, Yuxiang Wu*, Fudi Wang*. Fighting age-related orthopedic diseases: focusing on ferroptosis. Bone Research. 2023, 11(1):12. DOI: 10.1038/s41413-023-00247-y; PMID: 36854703. 【Cover Paper】影響因子：13.362 /Q1; 被引次數：16次【封面論文: 玉兔搗藥解讀骨疾病鐵死亡調控】（全文Link：https://www.nature.com/articles/s41413-023-00247-y）

183. Xuexian Fang*, Jiawei Zhang, You Li, Yijing Song, Yingying Yu, Zhaoxian Cai, Fuzhi Lian, Jun Yang, Junxia Min, Fudi Wang*. Malic Enzyme 1 as a Novel Anti-Ferroptotic Regulator in Hepatic Ischemia/Reperfusion Injury. Advanced Science. 2023, 10(13): e2205436. DOI: 10.1002/advs.202205436; PMID: 36840630. 【Frontispiece】影響因子：17.521 /Q1; 被引次數：11次【內封面論文：精忠報國岳飛闡釋ME1基因保護肝臟的重要功能】

（封面Link：https://onlinelibrary.wiley.com/doi/10.1002/advs.202370079）

182. Qian Wu, Euclides Sacomboio, Lara Valente de Souza, Rui Martins, Jamil Kitoko, Sílvia Cardoso, Temitope W Ademolue, Tiago Paixão, Jaakko Lehtimäki, Ana Figueiredo, Caren Norden, Pierre-Louis Tharaux, Guenter Weiss, Fudi Wang, Susana Ramos*. Miguel P Soares*. Renal control of life-threatening malarial anemia. Cell Reports. 2023, 42(2):112057. DOI: 10.1016/j.celrep.2023.112057; PMID: 36735532. Epub ahead of print. 影響因子：9.995 /Q1; 被引次數：2次

181. Yuan Gao, Tao Wang, Ying Cheng, Yumin Wu, Luwen Zhu, Zhiya Gu, Youzhuang Wu, Luwei Cai, Yimin Wu, Yidan Zhang, Cheng Gao, Lili Li, Jing Li, Qianqian Li, Zufeng Wang, Ying Wang, Fudi Wang*, Chengliang Luo*, Luyang Tao*. Melatonin ameliorates neurological deficits through MT2/IL-33/ferritin H signaling-mediated inhibition of neuroinflammation and ferroptosis after traumatic brain injury. Free Radic Biol Med. 2023, 199:97-112. DOI: 10.1016/j.freeradbiomed.2023.02.014; PMID: 36805045影響因子：8.101 /Q1; 被引次數：9次

180. Huiwen Zheng #, Xin Guo #, Shaomeng Kang #, Zhongda Li, Tian Tian, Jianhua Li, Fudi Wang, Peng Yu, Shiyang Chang, Yan-Zhong Chang*. Cdh5-mediated Fpn1 deletion exerts neuroprotective effects during the acute phase and inhibitory effects during the recovery phase of ischemic stroke. Cell Death Dis. 2023, 14(2):161. DOI: 10.1038/s41419-023-05688-1; PMID: 36841833. 影響因子：9.685 /Q1; 被引次數：4次

179. Xuexian Fang, Hossein Ardehali, Junxia Min*, Fudi Wang*. The molecular and metabolic landscape of iron and ferroptosis in heart disease. Nature Reviews Cardiology. 2023, 20(1):7-23. DOI: 10.1038/s41569-022-00735-4; PMID: 35788564. 【Cover Paper, Hot Paper】影響因子49.421 /Q1; 被引次數：179次【封面論文: 鐵離子破壞細胞引發鐵死亡發生的模式圖】【高被引論文/熱點論文】

（全文：https://www.nature.com/articles/s41569-022-00735-4）

178. Changzhou Feng, Ningzhe Li, Xibo Hu, Yinyin Xie, Qiuhua Huang, Jianming Zhang, Zhu Chen, Saijuan Chen, Fudi Wang*, Xiaojian Sun*. The LIFR-targeting small molecules EC330/EC359 are potent ferroptosis inducers. Genes Dis. 2022;10(3):735-738. doi: 10.1016/j.gendis.2022.10.016.影響因子：6.8 /Q1; 被引次數：2次

177. Tianze Xu, Jing Cai, Lei Wang, Li Xu, Hongting Zhao, Fudi Wang, Esther Meyron-Holtz, Fanis Missirlis, Tong Qiao, Kuanyu Li. Aging-related iron deposit prevents the benefits of HRT from late postmenopausal atherosclerosis. eLife. 2022. DOI: 10.1101/2022.06.24.497502. 影響因子：8.713 /Q1; 被引次數：0次

176. Na Li, Peng An, Jifeng Wang, Tingting Zhang, Xiaoqing Qing, Bowen Wu, Lang Sun, Xiang Ding, Lili Niu, Zhensheng Xie, Mengmeng Zhang, Xiaojing Guo, Xiulan Chen, Tanxi Cai, Jianming Luo, Fudi Wang*, Fuquan Yang*. Plasma proteome profiling combined with clinical and genetic features reveals the pathophysiological characteristics of β-thalassemia. iScience. 2022, 25(4):104091. DOI: 10.1016/j.isci.2022.104091; PMID: 35378860.影響因子6.107/Q1; 被引次數：3次

175. Hongen Meng, Rong Wang, Zijun Song, Fudi Wang*. Causal Effects of Circulating Lipid Traits on Epithelial Ovarian Cancer: A Two-Sample Mendelian Randomization Study. Metabolites. 2022, 12(12):1175. DOI: 10.3390/metabo12121175; PMID: 36557213. 影響因子5.581/Q2; 被引次數：0次

174. Xin Shen，Yingying Yu，Junyi Chen，Jie Shen，Jinming Zhang，Fudi Wang*, Junxia Min*. Targeting ferroptosis as a potential prevention and treatment strategy for human diseases (in Chinese). Sci Sin Vitae. 2022, 52: 1815–1826. DOI: 10.1360/SSV-2022-0241. 沈馨, 餘盈盈, 陳峻逸, 沈潔, 張金明, 王福俤, 閔軍霞, 靶向鐵死亡防治重大疾病的轉化醫學研究, 中國科學:生命科學. 2022, 52(12): 1815-1826. 被引次數：0次

173. Ying Cheng, Yuan Gao, Jing Li, Tongyu Rui, Qianqian Li, Huan Chen, Bowen Jia, Yiting Song, Zhiya Gu, Tao Wang, Cheng Gao, Ying Wang, Zufeng Wang, Fudi Wang*, Luyang Tao*, Chengliang Luo*. TrkB agonist N-acetyl serotonin promotes functional recovery after traumatic brain injury by suppressing ferroptosis via the PI3K/Akt/Nrf2/Ferritin H pathway. Free Radical Biology and Medicine. 2023 ,194:184-198. DOI: 10.1016/j.freeradbiomed.2022.12.002; PMID: 36493983. 影響因子8.101/Q1; 被引次數：13次

172. Liyun Chen#, Junxia Min*, Fudi Wang*. Copper homeostasis and cuproptosis in health and disease. Signal Transduction and Targeted Therapy. 2022, 7(1):378. DOI: 10.1038/s41392-022-01229-y; PMID: 36414625.【Highly Cited Paper】影響因子38.104/Q1; 被引次數：169次 【高被引論文】

171. Xinquan Yang#, Nicholas K Kawasaki#, Junxia Min*, Takashi Matsui*, Fudi Wang*. Ferroptosis in heart failure. Journal of Molecular and Cellular Cardiology. 2022, 173:141-153. DOI: 10.1016/j.yjmcc.2022.10.004; PMID: 36273661. 【Cover Paper】影響因子5.763/Q2; 被引次數：26次 【封面論文: 中國剪紙展示“鐵-虎-心臟”闡釋心臟疾病的鐵死亡調控特徵；2022中國虎年】

（全文Link：https://www.jmcc-online.com/article/S0022-2828(22)00537-5/fulltext）

170. Zhidan Xia #*, Xiu Yang #, Xinying Bi, Xiujuan Tong, Junxia Min, Fudi Wang*. Zinc transporter Slc30a1 regulates melanocyte development by interacting with mt2 in zebrafish. European Journal of Cell Biology. 2022, 101(4):151272. DOI: 10.1016/j.ejcb.2022.151272; PMID: 36063588. 影響因子6.020/Q2; 被引次數：2次

169. Dahang Li#, Shan Xu#, Li Jiang#, Yunxing Su, Junxia Min*, Fudi Wang*. Physiological functions of iron exporter Ferroportin and its regulatory mechanism. Chinese Bulletin of Life Sciences. 2022, 34(7): 754-777. 【Cover Paper】李大航#, 徐杉#, 蔣麗#, 蘇韻星, 閔軍霞, 王福俤*, 鐵泵蛋白Ferroportin生理功能及其調控機制研究進展.生命科學. 2022. 被引次數：0次【封面論文: FPN蛋白泵鐵功能模式圖】

168. Linhao You, Pan-Pan Yu, Tianyu Dong, Wenhuan Guo, Shiyang Chang, Bingjie Zheng, Yunzhe Ci, Fudi Wang, Peng Yu*, Guofen Gao* & Yan-Zhong Chang*. Astrocyte-derived hepcidin controls iron traffic at the blood-brain-barrier via regulating ferroportin 1 of microvascular endothelial cells. Cell Death & Disease. 2022, 13(8):667. DOI: 10.1038/s41419-022-05043-w; PMID: 35915080. 影響因子9.685 /Q1; 被引次數：16次

167. Fudi Wang*. Fighting the SARS-CoV-2 Pandemic: Focusing a New Lens on COVID-19. Research. 2022, 2022: 9879646. DOI: 10.34133/2022/9879646; PMID: 35966758. 【Editorial, Cover Paper】專家評述. 影響因子11.036 /Q1; 被引次數：2次【專輯特邀主編; 封面評述：新冠病毒蛋白三D圖像】

（全文Link：https://spj.science.org/doi/10.34133/2022/9879646）

166. Hongxiao Wang, Zijun Song, Enjun Xie, Junyi Chen, Biyao Tang, Fudi Wang*, Junxia Min*. Targeting the LSD1-G9a-ER Stress Pathway as a Novel Therapeutic Strategy for Esophageal Squamous Cell Carcinoma. Research. 2022, 2022:9814652. DOI: 10.34133/2022/9814652. PMID: 35707047. 【Commented Paper】 影響因子11.036 /Q1; 被引次數：5次【專家點評論文Commentary】

165. Hongen Meng, Li Jiang, Zijun Song, Fudi Wang*. Causal Associations of Circulating Lipids with Osteoarthritis: A Bidirectional Mendelian Randomization Study. Nutrients. 2022, 14(7):1327. DOI: 10.3390/nu14071327; PMID: 35405941. 影響因子6.706 /Q1; 被引次數：16次

164. Na Li# Peng An#, Jifeng Wang#, Tingting Zhang, Xiaoqing Qing, Bowen Wu, Lang Sun, Xiang Ding, Lili Niu, Zhensheng Xie, Mengmeng Zhang, Xiaojing Guo, Xiulan Chen, Tanxi Cai, Jianming Luo, Fudi Wang*, Fuquan Yang*. Plasma proteome profiling combined with clinical and genetic features reveals the pathophysiological characteristics of b-thalassemia. IScience. 2022, 25(4):104091. DOI: 10.1016/j.isci.2022.104091; PMID: 35378860.影響因子6.107/Q1; 被引次數：3次

163. Yasen Maimaitiyiming#, Tao Yang#, Qian Qian Wang#, Yan Feng, Zhi Chen, Mikael Björklund, Fudi Wang, Chonggao Hu*, Chih-Hung Hsu*, Hua Naranmandura*. Heat Treatment Promotes Ubiquitin-Mediated Proteolysis of SARS-CoV-2 RNA Polymerase and Decreases Viral Load. Research. 2022, 2022:9802969. DOI: 10.34133/2022/9802969; PMID: 35321260. 影響因子11.036/Q1; 被引次數：7次

162. Renhong Yan#, Enjun Xie#, Yaning Li#, Jin Li#, Yuanyuan Zhang, Ximin Chi, Xueping Hu, Lei Xu, Tingjun Hou, Brent R. Stockwell, Junxia Min*, Qiang Zhou*, Fudi Wang*. The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis. Cell Research. 2022, 32(7):687-690. DOI: 10.1038/s41422-022-00642-w; PMID: 35352032. 【Highly Cited Paper】影響因子46.297 /Q1; 被引次數：40次（全文Link: https://www.nature.com/articles/s41422-022-00642-w）

161. Sixiao He, Ru Li, Yanmei Peng, Ziqing Wang, Junhao Huang, Hongen Meng, Junxia Min, Fudi Wang*, Qiang Ma*. ACSL4 contributes to ferroptosis-mediated rhabdomyolysis in exertional heat stroke. J Cachexia Sarcopenia Muscle. 2022, 13(3):1717-1730. DOI: 10.1002/jcsm.12953; PMID: 35243801. 【Highly Cited Paper】影響因子12.063/Q1）被引次數：28次 【高被引論文】

(全文Link：https://onlinelibrary.wiley.com/doi/full/10.1002/jcsm.12953)

160. Fudi Wang#, Junxia Min#, Chaodong Ge#. Letter by Wang et al Regarding Article, "HINT1 (Histidine Triad Nucleotide-Binding Protein 1) Attenuates Cardiac Hypertrophy Via Suppressing HOXA5 (Homeobox A5) Expression". Circulation, 2022, 145(8):e149-e150. DOI: 10.1161/CIRCULATIONAHA.121.057235; PMID: 35188795. 影響因子：39.918 /Q1; 被引次數：0次

159. Huanhuan Zhao#, Jun Lu#, Tong Yan#, Fei Han#, Jie Sun, Xiaolin Yin, Liting Cheng, Chao Shen, Mark Wunderlich, Weina Yun, Lingling Yang, Liyun Chen, Dan Su, Stefan K.Bohlander, Fudi Wang, James C.Mulloy, Chong Li, Jianjun Chen, He Huang, Xi Jiang*. Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2. Cell Reports. 2022, 38(4):110253. DOI: 10.1016/j.celrep.2021.110253. PMID: 35081358. 影響因子：9.995 /Q1; 被引次數：6次

158. Junyi Chen#, Xiaopeng Li#, Chaodong Ge#, Junxia Min*, Fudi Wang*. The multifaceted role of ferroptosis in liver disease. Cell Death & Differentiation. 2022, 29(3):467-480. DOI: 10.1038/s41418-022-00941-0. PMID: 35075250. 【Highly Cited Paper】 影響因子12.067/Q1; 被引次數：165次【高被引論文】

（全文Link：https://www.nature.com/articles/s41418-022-00941-0）

157. Gong Feng, Christopher D Byrne, Giocanni Targher, Fudi Wang*, Ming-Hua Zheng*. Ferroptosis and metabolic dysfunction-associated fatty liver disease: Is there a link? Liver International. 2022, 42(7):1496-1502. DOI: 10.1111/liv.15163; PMID: 35007392 影響因子8.754/Q1; 被引次數：22次【封面論文】

（全文Link：https://onlinelibrary.wiley.com/doi/10.1111/liv.15163）

156. Huirong Lin#, Yu Zhou#, Jiaming Wang, Huimeng Wang, Tianhong Yao, Hu Chen, Huili Zheng, Yang Zhang, En Ren, Lai Jiang, Chengchao Chu, Xiaoyuan Chen, Jingsong Mao*, Fudi Wang*, Gang Liu*. Repurposing ICG enables MR/PA imaging signal amplification and iron depletion for iron-overload disorders. Science Advances. 2021, 7(51):eabl5862. DOI: 10.1126/sciadv.abl5862; PMID: 34919434. 影響因子14.957/Q1; 被引次數：17次

155. Qian Hu, Yifan Zhang, Huiling Lou, Zexian Ou, Jin Liu, Wentao Duan, Hao Wang, Yuanlong Ge, Junxia Min, Fudi Wang*, Zhenyu Ju*. GPX4 and vitamin E cooperatively protect hematopoietic stem and progenitor cells from lipid peroxidation and ferroptosis. Cell Death & Disease, 2021, 12(7):706. DOI: 10.1038/s41419-021-04008-9; PMID: 34267193. 影響因子9.685 /Q1; 被引次數：65次

154. Ran Xue, Qianwen Li, Yaping Geng, Hao Wang, Fudi Wang, Shenshen Zhang*. British Journal of Nutrition. Abdominal obesity and risk of CVD: a dose-response meta-analysis of thirty-one prospective studies. 2021, 126(9):1420-1430. DOI: 10.1017/S0007114521000064; PMID: 33431092. 影響因子4.125/Q3; 被引次數：32次

153. 彭雲^#, 李洋^#, 石亞菲, 任怡靜, 王福俤^*.金屬轉運蛋白SLC39A8的功能及作用機制研究進展. 生命科學，2021,33(11):1318-1321 (Yun Peng#, Yang Li#, Yafei Shi, YIjing Ren, Fudi Wang*. Research progress in physiological functions and molecular mechanisms of metal transporter SLC39A8. Chinese Bulletin of Life Sciences. 2021, 33(11):1318-1321) 【Cover Paper】被引次數：0次 【封面論文: SLC39A8突變引發人類疾病模式圖】

封面描述: 金屬離子轉運蛋白SLC39A8位於染色體4q24區 域，SLC39A8 1171G>A突變可引起克羅恩病(Crohn’s disease)、精神分裂症 (Schizophrenia)、青少年特發性脊柱側凸(Adolescent idiopathic scoliosis)、肥胖(Obesity)、脂肪性肝炎(Steatohepatitis) 及擴張型心肌病(Dilated cardiomyopathy) 等多種遺傳病。

152. Zhidan Xia#, Xinying Bi#, Sisi Yang, Xiu Yang, Zijun Song, Jiayu Wei, Pengfei Xu, Lothar Rink, Junxia Min*, Fudi Wang*. Metal transporter Slc30a1 controls pharyngeal neural crest differentiation via the zinc-Snai2-Jag1 cascade.MedComm. 2021, 2(4):778–797. DOI: 10.1002/mco2.91; PMID: 34977877. 【Cover Paper】成果揭示轉運蛋白slc30a1及鋅離子在胚胎下頜軟骨發育重要功能及極細調控機制。被引次數：4次【封面論文: 斑馬魚幼魚下顎軟骨染色】

（全文Link: https://onlinelibrary.wiley.com/doi/full/10.1002/mco2.91）

151. Li Jiang#, Jiaming Wang#, Kai Wang, Hao Wang, Qian Wu, Cong Yang, Yingying Yu, Pu Ni, Yueyang Zhong, Zijun Song, Enjun Xie, Ronggui Hu, Junxia Min*, Fudi Wang*. RNF217 regulates iron homeostasis through its E3 ubiquitin ligase activity bymodulating ferroportin degradation. Blood. 2021, 138 (8): 689–705. DOI: 10.1182/blood.2020008986; PMID: 33895792. 【Cover Paper, Highly Cited Paper， Commented Paper】影響因子25.476/Q1;被引次數：54次 【封面論文/亮點評述: Fpn和Rnf217蛋白在巨噬細胞的表達分佈的免疫熒光染色】Blood、STTT及Faculty Opinions被亮點評述。

BLOOD同期評述： Nermi L. Parrow, Robert E. Fleming. RNF217: brokering ferroportin degradation. Blood (2021) 138 (8): 593–5942. https://ashpublications.org/blood/article/138/8/593/476619/RNF217-brokering-ferroportin-degradation。亮點點評作者為鐵生物學領域國際著名科學家Robert E. Fleming教授。

STTT亮點點評： Tomas Ganz. New regulators of systemic iron homeostasis. Sig Transduct Target Ther 6, 280 (2021). https://doi.org/10.1038/s41392-021-00696-z https://www.nature.com/articles/s41392-021-00696-z。該亮點點評作者為鐵生物學領域國際頂尖科學家Tomas Ganz教授。

150. Fudi Wang*and Junxia Min*. DHODH tangoing with GPX4 on the ferroptotic stage. Signal Transduction and Targeted Therapy. 2021, 6(1):244. DOI: 10.1038/s41392-021-00656-7; PMID: 34145214. 【Research Highlights】影響因子38.104/Q1; 被引次數：29次【特邀評述】

149. Xin Zong, Xiao Xiao, Bin Shen, Qin Jiang, Hong Wang, Zeqing Lu, Fengqin Wang, Mingliang Jin, Junxia Min, Fudi Wang*and Yizheng Wang*. The N6-methyladenosine RNA-binding protein YTHDF1 modulates the translation of TRAF6 to mediate the intestinal immune response. Nucleic Acids Research. 2021, 49(10):5537-5552. DOI: 10.1093/nar/gkab343; PMID: 33999206.【Hot Paper】影響因子19.16/Q1; 被引次數：71次 【高被引論文/熱點論文】

148. Lei Yan, Pei Han, Jin Man, Yongmei Tian, Fudi Wang*, Jia Wang*. Discovery of lipid profiles of type 2 diabetes associated with hyperlipidemia using untargeted UPLC Q-TOF/MS-based lipidomics approach. Clinica Chimica Acta. 2021, 520:53-62. DOI: 10.1016/j.cca.2021.05.031; PMID: 34077755. 影響因子6.314/Q1; 被引次數：12次

147. Pei Han, Jin Man, Yun Hao, Longjie Wu, Jia Wang, Wenjie Yang, Fudi Wang*, Yongmei Tian*. Metabolomic analysis of plasma from normal-weight adults with hypo-HDL cholesterolemia by UPLC–QTOF MS. Biomedical Chromatography. 2021, 35(6):e5073. DOI: 10.1002/bmc.5073; PMID: 33453122. 影響因子 1.911/Q4）被引次數：1次

146. Xinhui Wang*, Xuexian Fang, Wanru Zheng, Jiahui Zhou, Zijun Song, Mingqing Xu*, Junxia Min*, Fudi Wang*. Genetic support of a causal relationship between iron status and type 2 diabetes: a Mendelian randomization study. The Journal of Clinical Endocrinology & Metabolism. 2021, 106(11):e4641-e4651. DOI: 10.1210/clinem/dgab454; PMID: 34147035. 【Highly Cited Paper】該成果被Faculty Opinions同行科學家高度推薦；點評專家為哈佛醫學院Joslin糖尿病中心教授及資深臨牀專家Om P Ganda博士。影響因子6.134/Q1;被引次數：85次 【高被引論文】

(全文Link：https://academic.oup.com/jcem/article/106/11/e4641/6306518)

145. Fudi Wang. Entangling of Nutrition, Metabolism, and Immunity. Infectious Microbes and Diseases. 2021, 3(4):173–174. DOI: 10.1097/IM9. 0000000000000075. 被引次數：0次【專家評述Editorial/專輯特邀主編】

144. Pinanong Na-Phatthalung, Junxia Min, Fudi Wang*. Macrophage-mediated defensive mechanisms involving zinc homeostasis in bacterial infection. Infectious Microbes and Diseases. 2021, 3(4):175–182. DOI: 10.1097/IM9.0000000000000058.被引次數：4次

143. Shan Xu, Junxia Min*, Fudi Wang*. Ferroptosis: an emerging player in immune cells. Science Bulletin. 2021, 66(22): 2257-2260. DOI: 10.1016/j.scib.2021.02.026; PMID: 36654451. 影響因子20.577 /Q1;被引次數：45次

142. Qingdian Mu#, Liyun Chen#, Xiaotong Gao, Shuying Shen, Wenjing Sheng, Junxia Min*, Fudi Wang*. The role of iron homeostasis in remodeling immune function and regulating inflammatory disease. Science Bulletin. 2021, 66(17):1806-1816. DOI: 10.1016/j.scib.2021.02.010; PMID: 36654387.影響因子20.577 /Q1; 被引次數：61次

141. Xiaomin Liu, Zijun Song, Yan Li, Yao Yao, Mingyan Fang, Chen Bai, Peng An, Huashuai Chen, Zhihua Chen, Biyao Tang, Juan Shen, Xiaotong Gao, Mingrong Zhang, Pengyu Chen, Tao Zhang, Huijue Jia, Xiao Liu, Yong Hou, Huanming Yang, Jian Wang, Fudi Wang, Xun Xu, Junxia Min, Chao Nie, Yi Zeng. Integrated genetic analyses revealed novel human longevity loci and reduced risks of multiple diseases in a cohort study of 15,651 Chinese individuals. Aging Cell. 2021, 20(3):e13323. DOI: 10.1111/acel.13323; PMID: 33657282. 影響因子11.005/Q1; 被引次數：29次

140. Qian Wu#, Qingdian Mu#, Zhidan Xia#, Junxia Min*, Fudi Wang*. Manganese homeostasis at the host-pathogen interface and in the host immune system. Seminars in Cell & Developmental Biology. 2021,115:45-53. DOI: 10.1016/j.semcdb.2020.12.006; PMID: 33419608. 影響因子7.499/Q1; 被引次數：23次

139. Wen-Dai Bao, Pei Pang, Xiao-Ting Zhou, Fan Hu, Wan Xiong, Kai Chen, Jing Wang, Fudi Wang, Dong Xie, Ya-Zhuo Hu, Zhi-Tao Han, Hong-Hong Zhang, Wang-Xia Wang, Peter T Nelson, Jian-Guo Chen, Youming Lu, Heng-Ye Man, Dan Liu, Ling-Qiang Zhu*. Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer's disease. Cell Death & Differentiation. 2021, 28(5):1548-1562. DOI: 10.1038/s41418-020-00685-9; PMID: 33398092. 【Hot Paper】影響因子12.067 /Q1; 被引次數：259次 【高被引論文/熱點論文】

(全文Link：https://www.nature.com/articles/s41418-020-00685-9)

138. Hailong Wang, Xiaopeng Wu, Xiaoxin Wu, Juan Liu, Yan Yan, Fudi Wang, Lanjuan Li, Jiyong Zhou, Min Liao. Iron status is linked to disease severity after avian influenza virus H7N9 infection. Asia Pac J Clin Nutr. 2020, 29(3):593-602. DOI: 10.6133/apjcn.202009_29(3).0019. PMID: 32990620. 影響因子1.322 /Q4; 被引次數：3次

137. Jing Cai, Meng Zhang, Yutong Liu, Huihui Li, Longcheng Shang, Tianze Xu, Zhipeng Chen, Fudi Wang, Tong Qiao*, Kuanyu Li*. Iron accumulation in macrophages promotes the formation of foam cells and development of atherosclerosis. Cell & Bioscience. 2020, 10(1):137. DOI:10.1186/s13578-020-00500-5; PMID: 33292517. 影響因子9.584/Q1; 被引次數：33次

136. Mengyao Zhou#, Hao Wang#, Yanna Shang, Yang Li, Fudi Wang*. Molecular mechanisms and physiological functions of metal transporter SLC39A14. Chinese Bulletin of Life Sciences. 2020, 32(9):890-902 DOI: 10.13376/j.cbls/2020110. 【Cover Paper】 (周夢瑤#,王浩#,尚豔娜,李洋,王福俤*. 金屬轉運蛋白SLC39A14生理功能及作用機制研究進展. 生命科學，2020) 被引次數：0次 【封面論文: 三國演義五虎上將趙雲寓意SLC39A14的轉鐵、轉鋅、轉錳及調控鐵死亡的多種角色的優秀形象】

135. Tongyu Rui, Haochen Wang, Qianqian Li, Ying Cheng, Yuan Gao, Xuexian Fang, Xuying M, Guang Chen, Cheng Gao, Zhiya Gu, Shunchen Song, Jian Zhang, Chunling Wang, Zufeng Wang, Tao Wang, Mingyang Zhang, Junxia Min, Xiping Chen, Luyang Tao*, Fudi Wang*, Chengliang Luo*. Deletion of ferritin H in neurons counteracts the protective effect of melatonin against traumatic brain injury-induced ferroptosis. Journal of Pineal Research. 2021, 70(2):e12704. DOI: 10.1111/jpi.12704; PMID: 33206394. 影響因子12.081/Q1; 被引次數：99次

134. Lei Yang#, Hao Wang#, Xiang Yang#, Qian Wu, Peng An, Xi Jin, Weiwei Liu, Xin Huang, Yuzhu Li，Shiyu Yan, Shuying Shen, Tingbo Liang*, Junxia Min*, Fudi Wang*. Auranofin mitigates systemic iron overload and induces ferroptosis via distinct mechanisms. Signal Transduction and Targeted Therapy. 2020, 5(1):138. DOI: 10.1038/s41392-020-00253-0; PMID: 32732975.【Highly Cited Paper】 影響因子38.104/Q1; 被引次數：135次【高被引論文】

(全文Link：https://www.nature.com/articles/s41392-020-00253-0)

133. Yingying Yu#, Li Jiang#, Hao Wang, Zhe Shen, Qi Cheng, Pan Zhang, Jiaming Wang, Qian Wu, Xuexian Fang, Lingyan Duan, Shufen Wang, Kai Wang, Peng An, Tuo Shao, Raymond T. Chung, Shusen Zheng*, Junxia Min*,Fudi Wang*. Hepatic Transferrin Plays a Role in Systemic Iron Homeostasis and Liver Ferroptosis. Blood. 2020, 136(6):726-739.DOI:10.1182/blood.2019002907; PMID:32374849.【Cover Paper, Commented Paper, Highly Cited Paper】影響因子25.476/Q1; 被引次數：290次【高被引論文/封面論文】Blood同期評論：Iron turns to wild when the transferrin is away (全文Link：https://ashpublications.org/blood/article/136/6/726/454783/Hepatic-transferrin-plays-a-role-in-systemic-iron)

132. Juann Liu#, Xiaopeng Wu#, Hailong Wang#, Jiayu Wei#, Qian Wu, Xingbo Wang, Yan Yan, Jun Cui, Junxia Min,Fudi Wang*, Jiyong Zhou*. HFE inhibits type I IFNs signaling by targeting the SQSTM1-mediated MAVS autophagic degradation. Autophagy. 2021, 17(8):1962-1977. DOI: 10.1080/15548627.2020.1804683; PMID: 32746697. 影響因子13.391/Q1; 被引次數：30次

131. Xiang Yang#, Hongxiao Wang#, Enjun Xie, Biyao Tang, Qingdian Mu, Zijun Song, Junyi Chen, Fudi Wang, Junxia Min*. Rewiring ERBB3 and ERK signaling confers resistance to FGFR1 inhibition in gastrointestinal cancer harbored an ERBB3-E928G mutation. Protein & Cell. 2020, 11(12):915-920. DOI: 10.1007/s13238-020-00749-z.影響因子15.328/Q1; 被引次數：3次

130. Jin Li#, Xiaohan Pan#, Guihua Pan, Zijun Song, Yao He, Susu Zhang, Xueru Ye, Xiang Yang, Enjun Xie, Xinhui Wang, Xudong Mai, Xiangju Yin, Biyao Tang, Xuan Shu, Pengyu Chen, Xiaoshuang Dai, Ye Tian, Liheng Yao, Mulan Han, Guohuan Xu, Huijie Zhang, Jia Sun, Hong Chen, Fudi Wang*（Lead Contact）, Junxia Min*, Liwei Xie*. Transferrin Receptor 1 Regulates Thermogenic Capacity and Cell Fate in Brown/Beige Adipocytes. Advanced Science. 2020, 7(12):1903366. DOI: 10.1002/advs.201903366; PMID: 32596110. Frontispiece. 影響因子：17.521/Q1）被引次數：41次【封面論文: 賣火柴的小女孩寓意TFR1及鐵對產熱脂肪細胞命運調控的重要作用】

內封面論文Frontispiece: 賣火柴的小女孩

（封面Link：https://onlinelibrary.wiley.com/doi/10.1002/advs.202070066）

129. Zhidan Xia, Xinying Bi, Jia Lian, Wei Dai, Xuyan He, Lu Zhao, Junxia Min, Fudi Wang*. Slc39a5-mediated zinc homeostasis plays an essential role in venous angiogenesis in zebrafish. Open Biology. 2020, 10(10):200281. DOI:10.1098/rsob.200281; PMID: 33081634. 影響因子7.124/Q1;被引次數：9次

128. Liyun Chen, Qianwen Li, Xuexian Fang, Xinhui Wang, Junxia Min*, Fudi Wang*. Dietary Intake of Homocysteine Metabolism-Related B-Vitamins and the Risk of Stroke: A Dose-Response Meta-Analysis of Prospective Studies. Advances in Nutrition. 2020, 11(6):1510-1528. DOI: 10.1093/advances/nmaa061; PMID: 32503038. 影響因子11.567/Q1; 被引次數：28次

127. Wen-Dai Bao, Xiao-Ting Zhou, Lan-Ting Zhou, Fudi Wang, Xiaoping Yin, Youming Lu, Ling-Qiang Zhu, Dan Liu*. Targeting miR-124/Ferroportin signaling ameliorated neuronal cell death through inhibiting apoptosis and ferroptosis in aged intracerebral hemorrhage murine model. Aging Cell. 2020, 19(11):e13235. DOI: 10.1111/acel.13235; PMID:33068460. 影響因子11.005/Q1; 被引次數：101次

126. Weiwei Liu, Yongjuan Xin, Qianwen Li, Yanna Shang, Zhiguang Ping, Junxia Min, Catherine M Cahill, Jack T Rogers, Fudi Wang*. Biomarkers of environmental manganese exposure and associations with childhood neurodevelopment: a systematic review and meta-analysis. Environmental Health. 2020, 19(1):104. DOI: 10.1186/s12940-020-00659-x; PMID: 33008482. 影響因子7.123/Q2; 被引次數：41次

125. Xuexian Fang, Zhaoxian Cai, Hao Wang, Dan Han, Qi Cheng, Pan Zhang, Feng Gao, Yingying Yu, Zijun Song, Qian Wu, Peng An, Sicong Huang, Jianwei Pan, Hou-Zao Chen, Jinghai Chen, Andreas Linkermann, Junxia Min*, Fudi Wang*. Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis. Circulation Research. 2020, 127(4):486-501. DOI: 10.1161/CIRCRESAHA.120.316509; PMID:32349646. 影響因子23.213/Q1;被引次數：365次【高被引論文】

（全文Link：https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.120.316509）

124. Xinhui Wang#, Xuexian Fang#, Zhaoxian Cai#, Xiaotian Wu#, Xiaotong Gao#, Junxia Min*, Fudi Wang*. Comorbid Chronic Diseases and Acute Organ Injuries Are Strongly Correlated with Disease Severity and Mortality among COVID-19 Patients: A Systemic Review and Meta-Analysis. Research (Wash DC). 2020, 2020:2402961. DOI: 10.34133/2020/2402961; PMID:32377638. (亮點論文) 影響因子11.036/Q1; 被引次數：455次 【高被引論文/熱點論文】獲得年度優秀論文獎

123. Jiaying Chen#, Xinzhi Zhao#, Li Cui#, Guang He, Xinhui Wang, Fudi Wang, Shiwei Duan, Lin He, Qiang Li, Xiaodan Yu*, Fuquan Zhang*, Mingqing Xu*. Genetic regulatory subnetworks and key regulating genes in rat hippocampus perturbed by prenatal malnutrition: implications for major brain disorders. Aging (Albany NY). 2020, 12(9):8434-8458. DOI: 10.18632/aging.103150; PMID:32392183. 影響因子5.955 /Q2；被引次數：67次

122. Peng An#, Jiaming Wang#, Hao Wang, Li Jiang, Jia Wang, Junxia Min* and Fudi Wang*. Gnpat does not play an essential role in systemic iron homeostasis in murine model. Journal of Cellular and Molecular Medicine. 2020, 24(7):4118-4126. DOI: 10.1111/jcmm.15068. PMID: 32108988. 影響因子5.295/Q2; 被引次數：3次

121. Xuexian Fang, Jiayu Wei, Junxia Min, Fudi Wang*. Dietary intake of heme iron is Associated with Increased Cardiovascular Disease Risk: Reply to Dr. Bitterman. Nutrition. Metabolism & Cardiovascular Diseases. 2020, 30(6):1053-1055. DOI:10.1016/j.numecd.2020.03.007; PMID:32247532. 影響因子4.666/Q2; 被引次數：1次

120. Shufen Wang#, Xuyan He#, Qian Wu, Li Jiang, Liyun Chen, Yingying Yu, Pan Zhang, Xin Huang, Jia Wang, Zhenyu Ju, Junxia Min*, Fudi Wang*. Transferrin receptor 1-mediated iron uptake plays an essential role in hematopoiesis. Haematologica. 2020, 105(8):2071-2082. DOI:10.3324/haematol.2019.224899; PMID:31601687. 影響因子11.047/Q1; 被引次數：53次

119. Lingyan Duan, Xiangju Yin, Hongen Meng, Xuexian Fang, Junxia Min, Fudi Wang*. Progress on epigenetic regulation of iron homeostasis. Journal of Zhejiang University (medical sciences). 2020, 49(1):58-70. DOI:10. 3785 / j. issn. 1008-9292. 2020. 02. 05.（段玲豔,尹香菊,孟紅恩,方學賢,閔軍霞,王福俤*. 鐵穩態代謝表觀遺傳調控機制的研究進展. 浙江大學學報(醫學版) 2020）被引次數：6次

118. Junyi Chen, Xiang Yang, Xuexian Fang, Fudi Wang, Junxia Min*. The role of ferroptosis in chronic diseases. Journal of Zhejiang University (medical sciences). 2020, 49(1):44-57, DOI:10. 3785 / j. issn. 1008-9292. 2020. 02. 04 (陳峻逸,楊翔,方學賢，王福俤,閔軍霞*. 鐵死亡與重大慢性疾病. 浙江大學學報(醫學版) 2020)被引次數：6次

117. Jing Liu, Wei Liu, Yin Liu, Yang Miao, Yifan Guo, Haoyang Song, Fudi Wang, Hongyu Zhou, Tomas Ganz, Bing Yan, Sijin Liu. New thiazolidinones reduce iron overload in mouse models of hereditary hemochromatosis and β-thalassemia. Haematologica. 2019, 104(9):1768-1781. doi: 10.3324/haematol.2018.209874. Epub 2019 Feb 21. PMID: 30792208. 影響因子11.047 /Q1; 被引次數：23次

116. Yuhang Jiang#, Cuifeng Li#, Qian Wu#, Peng An, Laiquan Huang, Chen Chen, Xi Chen, Fan Zhang, Li Ma, Sanhong Liu, Hanqing He, Shuyun Xie, Yangbai Sun, Hanshao Liu, Yu Zhan, Yu Tao, Zhi Liu, Xiaohua Sun, Yiming Hu, Qi Wang, Deji Ye, Jie Zhang, Shanhua Zou, Ying Wang, Gang Wei, Yongzhong Liu, Yufang Shi, Y. Eugene Chin, Yongqiang Hao, Fudi Wang*, Xiaoren Zhang*. Iron-dependent histone 3 lysine 9 demethylation controls B cell proliferation and humoral immune responses. Nature Communications. 2019 ,10(1): 2935. DOI: 10.1038/s41467-019-11002-5; PMID: 31270335. 影響因子17.694/Q1; 被引次數：113次

115.Xinhui Wang#, Wenhui Wu#, Wanru Zheng, Xuexian Fang, Liyun Chen, Lothar Rink, Junxia Min*, Fudi Wang*. Zinc supplementation improves glycemic control for diabetes prevention and management: A systematic review and meta-analysis of randomized controlled trials. The American Journal of Clinical Nutrition. 2019, 110(1):76-90. DOI: 10.1093/ajcn/nqz041; PMID:31161192. 影響因子8.472/Q1; 被引次數：114次

Editor’s Choice/主編推薦論文(全文鏈接：https://www.sciencedirect.com/science/article/pii/S0002916522011546?via%3Dihub)

114. Li Jiang#, Kai Wang#, Kenneth Lo #, Yueyang Zhong, Aimin Yang, Xuexian Fang, Hailati Akezhuoli, Zijun Song, Liyun Chen, Peng An, Minqing Xu*, Junxia Min*, Fudi Wang*. Sex-specific Association of Circulating Ferritin Levels and Risk of Type 2 Diabetes: A Dose-response Meta-analysis of Prospective Studies. The Journal of Clinical Endocrinology and Metabolism. 2019, 104(10):4539-4551. DOI: 10.1210/jc.2019-00495; PMID: 31074789. 影響因子6.134/Q1; 被引次數：61次

113. Xuexian Fang, Hao Wang, Dan Han, Enjun Xie, Xiang Yang, Jiayu Wei, Shanshan Gu, Feng Gao, Nali Zhu, Xiangju Yin, Qi Cheng, Pan Zhang, Wei Dai, Jinghai Chen, Fuquan Yang, Huang-Tian Yang, Andreas Linkermann*, Wei Gu*, Junxia Min* and Fudi Wang*. Ferroptosis as a target for protection against cardiomyopathy. Proceedings of the National Academy of Sciences USA. 2019, 116(7):2672-2680. DOI: 10.1073/pnas.1821022116; PMID: 30692261. 影響因子12.779/Q1; 被引次數：1187次 【高被引論文/熱點論文】

（全文Link：https://www.pnas.org/doi/abs/10.1073/pnas.1821022116?url_ver=Z39.88-2003&rfr_id=ori%3Arid%3Acrossref.org&rfr_dat=cr_pub++0pubmed）

Cell Research：Marcus Conrad教授發表Research Highlight評論

Broken hearts: Iron overload, ferroptosis and cardiomyopathy

Circulation發佈新聞: New Target to Protect Against Cardiomyopathy

112. Shicheng Guo, Shuai Jiang, Narendranath Epperla, Yanyun Ma, Mehdi Maadooliat, Zhan Ye, Brent Olson, Minghua Wang, Terrie Kitchner, Jeffrey Joyce, Peng An, Fudi Wang, Robert Strenn, Joseph J. Mazza, Jennifer K. Meece, Wenyu Wu, Li Jin, Judith A. Smith, Jiucun Wang* and Steven J. Schrodi*. A gene-based recessive diplotype exome scan discovers FGF6, a novel hepcidin-regulating iron-metabolism gene. Blood. 2019, 133(17):1888-1898. DOI:10.1182/blood-2018-10-879585. 影響因子25.476/Q1; 被引次數：15次

111. Huimin Li#*, Xinhui Wang#, Xinyue Lu, Hongxin Zhu, Sheng Li, Shiwei Duan, Xinzhi Zhao, Fuquan Zhang, Gil Alterovitz, Fudi Wang, Qiang Li, Xiao-Li Tian*, Qingmin Xu*. Co-expression network analysis identified hub genes critical to triglyceride and free fatty acid metabolism as key regulators of age-related vascular dysfunction in mice. Aging (Albany NY). 2019, 11(18):7620-7638. DOI: 10.18632/aging.102275; PMID: 31514170. 影響因子5.955/Q2; 被引次數：55次

110. Peng Zhang, Jian He, Fei Wang, Jing Gong, Lu Wang, Qian Wu, Wenjiong Li, Hongju Liu, Jing Wang, Kunshan Zhang, Mao Li, Xusheng Huang, Chuanqiang Pu, Ying Li, Fengjie Jiang, Fudi Wang*, Junxia Min*, Xiaoping Chen*. Hemojuvelin is a novel suppressor of Duchenne muscular dystrophy and aging-related muscle wasting. Journal of Cachexia, Sarcopenia and Muscle. 2019, 10(3):557-573. DOI: 10.1002/jcsm.12414; PMID: 30884219.影響因子12.063/Q1; 被引次數：21次

109. Guanyu Li #, Yiran Zhang #, Enjun Xie, Xiang Yang, Hao Wang, Xijuan Wang, Wenwen Li, Zijun Song, Qingdian Mu, Weihua Zhan, Qian Wu, Juqing Huang, Yufeng Chen, Ying Zhang, Fudi Wang, Junxia Min*. Functional characterization of a potent anti-tumor polysaccharide in a mouse model of gastric cancer. Life Sciences. 2019, 219:11-19. DOI: 10.1016/j.lfs.2019.01.003; PMID: 30611785.影響因子6.780/Q1; 被引次數：18次

108. Xuexian Fang, Zhaoxian Cai, Hao Wang, Junxia Min and Fudi Wang*. Role of iron overload and ferroptosis in heart disease. Chinese Science Bulletin. 2019, 64. DOI: 10.1360/TB-2019-0242. COVER (方學賢, 蔡昭賢, 王浩等. 鐵過載及鐵死亡在心臟疾病中的研究進展. 科學通報, 2019, 64 封面）（被引次數：4次）【封面論文: 女媧補天寓意靶向鐵死亡防治疾病的重大意義】

論文封面：女媧補天該封面榮獲2019年度中國科學雜誌社年度最佳封面（年度唯一）

107. Jiang Sheng, Lu Zhao*, and Fudi Wang*. Research progress of zinc homeostasis in hematopoiesis. Chinese Bulletin of Life Sciences. 2019, 30(10). DOI: 10.13376/j.cbls/2019121. COVER (盛健,趙璐*,王福俤*. 鋅穩態代謝調控造血發育的研究進展. 生命科學，2019，封面) 被引次數：1次;【封面論文: 鋅離子轉運蛋白在細胞的分佈模式圖】論文封面：鋅穩態代謝調控造血發育的研究進展

106. Hong Gao #, Wei Dai #, Lu Zhao*, Junxia Min*, Fudi Wang*. The Role of Zinc and Zinc Homeostasis in Macrophage Function. Journal of Immunology Research. 2018, 2018:6872621. DOI: 10.1155/2018/6872621; PMID: 30622979. 影響因子4.493/Q3; 被引次數：151次

105. Kuo Zhang, Yuying Zhang, Lijie Gu, Miaomiao Lan, Chuncheng Liu, Meng Wang, Yang Su, Mengxu Ge, Tongtong Wang, Yingying Yu, Chang Liu, Lei Li, Qiuyan Li, Yaofeng Zhao, Zhengquan Yu, Fudi Wang, Ning Li, Qingyong Meng*. Islr regulates canonical Wnt signaling-mediated skeletal muscle regeneration by stabilizing Dishevelled-2 and preventing autophagy. Nature Communications. 2018, 9(1):5129.DOI: 10.1038/s41467-018-07638-4; PMID: 30510196. 影響因子17.694/Q1; 被引次數：73次

104. Haoyang Song, Shuping Zhang, Xia Sun, Jing Liu, Yakun Wu, Wenli Guo, Fudi Wang, Xiaojuan Ou, Min Cong, Erhu Jin, Wenyong Li*, and Sijin Liu*. Distinct Iron Deposition Profiles of Liver Zones in Various Models with Iron Homeostasis Disorders. Advanced Science (Weinh). 2018, 5(11):1800866. DOI: 10.1002/advs.201800866; PMID: 30479929. 影響因子：17.521/Q1; 被引次數：5次

103. Xuexian Fang, Dan Han, Qi Cheng, Pan Zhang, Chunhui Zhao, Junxia Min, Fudi Wang*. Association of Levels of Physical Activity with Risk of Parkinson Disease: A Systematic Review and Meta-analysis. JAMA Network Open. 2018, 1(5):e182421. DOI: 10.1001/jamanetworkopen.2018.2421; PMID: 30646166. 影響因子13.353/Q1; 被引次數：121次

配特邀評論: 斯坦福大學教授Lorene M. Nelson, PhD, MS

Physical Activity and Parkinson Disease Risk

102. Shanshan Xie, Juan Jin, Zhangqi Xu, Yuliang Huang, Wen Zhang, Lu Zhao, Li Jan Lo, Jinrong Peng, Wei Liu, Fudi Wang, Qiang Shu*, and Tianhua Zhou*. Centrosomal protein FOR20 is essential for cilia-dependent development in zebrafish embryos. FASEB Journal. 2019, 33(3):3613-3622. DOI: 10.1096/fj.201801235RR;PMID: 30475641. 影響因子5.834/Q1; 被引次數：10次

101. Jifei Ma#, Qianwen Li#, Xuexian Fang, Liyun Chen, Yuzhen Qiang, Jianyao Wang, Qingqing Wang, Junxia Min, Shenshen Zhang* and Fudi Wang*. Increased total iron and zinc intake and lower heme iron intake reduce the risk of esophageal cancer: A dose-response meta-analysis. Nutrition Research. 2018, 59:16-28. DOI: 10.1016/j.nutres.2018.07.007; PMID: 30442229. 影響因子3.876/Q3; 被引次數：18次

100. Martina Maywald, Fudi Wang, Lothar Rink *. The Intracellular Free Zinc Level Is Vital for Treg Function and a Feasible Tool to Discriminate between Treg and Activated Th Cells. International Journal of Molecular Sciences. 2018, 19(11):3575. DOI: 10.3390/ijms19113575; PMID: 30428511. 影響因子6.208/Q1; 被引次數：9次

99. Xuexian Fang, Junxia Min, Fudi Wang*. A dose-response association between serum ferritin and metabolic syndrome? Atherosclerosis. 2018, 279:130-131.DOI: 10.1016/j.atherosclerosis.2018.10.016. 影響因子6.847/Q1; 被引次數：6次

98. Xinhui Wang#, Hong Gao#, Wenhui Wu, Enjun Xie, Yingying Yu, Xuyan He, Jin Li, Xudong Wang, Xizhi Cao, Zhuoxian Meng, Ligong Chen*, Junxia Min* and Fudi Wang*. The zinc transporter Slc39a5 controls glucose sensing and insulin secretion in pancreatic β-cells via Sirt1- and Pgc-1α-mediated regulation of Glut2. Protein & Cell. 2019, 10(6):436-449. DOI: 10.1007/s13238-018-0580-1; PMID: 30324491. 影響因子15.328/Q1; 被引次數：32次

97. Vivek Venkataramani*, Thorsten R. Doeppner, Desiree Wilkommen, Catherine M. Cahill, Yong-juan Xin, Guilin Ye, Yanyan Liu, Adam Southon, Allegra Aron, Ho Yu Au-Yeung, Xudong Huang, Debomoy K. Lahiri, Fudi Wang, Ashley I. Bush, Gerald G. Wulf, Philipp Ströbel, Bernhard Michalke, Jack T. Rogers. Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin. Journal of Neurochemistry. 2018, 147(6):831-848. DOI: 10.1111/jnc.14580; PMID: 30152072. 影響因子5.546 /Q2; 被引次數：58次

96. Yuzhen Qiang #, Qaingwen Li#, Yongjuan Xin, Xuexian Fang, Yongmei Tian, Jifei Ma, Jianyao Wang, Qingqing Wang, Ruochen Zhang, Junhao Wang and Fudi Wang*. Intake of Dietary One-Carbon Metabolism-Related B Vitamins and the Risk of Esophageal Cancer: A Dose-Response Meta-Analysis. Nutrients. 2018, 147(6):831-848. DOI: 10.3390/nu10070835; PMID: 29954131. 影響因子6.706/Q1; 被引次數：30次

95. Xueqiao Wang, Xiaoqing Zheng, Juanlian Zhang, Shifeng Zhao, Zhigang Wang, Fudi Wang, Wenjun Shang, Jonathan Barasch, and Andong Qiu*. Physiological functions of Ferroportin in the regulation of renal iron recycling and ischemic acute kidney injury. The American Journal of Physiology-Renal Physiology. 2018 , 315(4):F1042-F1057. DOI: 10.1152/ajprenal.00072.2018; PMID: 29923765. 影響因子4.097 /Q2; 被引次數：35次

94. Xuexian Fang#, Jiayu Wei#, Xuyan He#, Jia Lian#, Dan Han, Peng An, Tianhua Zhou, Simin Liu, Fudi Wang*, Junxia Min*. Quantitative association between body mass index and the risk of cancer: A global Meta-analysis of prospective cohort studies. International Journal of Cancer. 2018, 143(7):1595-1603. DOI: 10.1002/ijc.31553; PMID: 29696630. 影響因子7.316 /Q1; 被引次數：103次

93. Peng An, Hao Wang, Qian Wu, Jiaming Wang, Zhidan Xia, Xuyan He, Xinhui Wang, Yan Chen, Junxia Min*, Fudi Wang*. Smad7 deficiency decreases iron and haemoglobin through hepcidin up-regulation by multilayer compensatory mechanisms. Journal of Cellular and Molecular Medicine. 2018, 233(9):7268-7278. DOI: 10.1002/jcp.26559; PMID: 29575577. 影響因子5.295/Q2; 被引次數：16次

92. Yingqi Zhang#, Xudong Wang#, Qian Wu, Hao Wang, Lu Zhao, Xinhui Wang, Mingdao Mu, Enjun Xie, Xuyan He, Dandan Shao, Yanna Shang, Yongrong Lai, Yelena Ginzburg, Junxia Min*, Fudi Wang*. Adenine alleviates iron overload by cAMP/PKA mediated hepatic hepcidin in mice. Journal of Cellular Physiology. 2018, 233(9):7268-7278. DOI: 10.1002/jcp.26559; PMID: 29600572. 影響因子6.513 /Q1; 被引次數：11次

91. Martina Maywald, Fudi Wang, Lothar Rink*. Zinc supplementation plays a crucial role in T helper 9 differentiation in allogeneic immune reactions and non-activated T cells. Journal of Trance Elements in Medicine and Biology. 2018, 50:482-488. DOI: 10.1016/j.jtemb.2018.02.004; PMID: 29439842. 影響因子3.995/Q3; 被引次數：42次

90. Xin Huang#, Ling-ling Li#, Jun-hao Wang#, Junxia Min*, and Fudi Wang*. Functional discoveries and mechanistic studies of manganese transporters. Chinese Bulletin of Life Sciences. 2018,30(06):603-614.DOI:10.13376/j.cbls/2018073. COVER (黃鑫，李玲玲，王君豪，閔軍霞，王福俤. 錳離子轉運蛋白的發現及功能機制研究進展.生命科學2018, 38(6). 封面：錳離子轉運蛋白的發現及功能機制研究進展 被引次數：4次【封面論文】

89. Jiaming Wang, Peng An, Hao Wang, Qian Wu, Xuexian Fang, Junxia Min, Fudi Wang*. Advances in iron homeostasis and ferromagnetic nanoparticles. Chinese Science Bulletin. 2019, 64(08):788-801. DOI: 10.1360/N972018-00707.(王佳明, 安鵬, 王浩, 吳謙, 方學賢, 閔軍霞, 王福俤. 鐵穩態代謝分子機制及鐵磁納米顆粒研究進展. 科學通報, 2018, 63) 被引次數：1次

88. Hong Gao#, Lu Zhao#, Hao Wang, Enjun Xie, Xinhui Wang, Qian Wu, Yingying Yu, Xuyan He, Hongbin Ji, Lothar Rink, Junxia Min* and Fudi Wang*. The Metal Transporter Slc39a10 Regulates Susceptibility to Inflammatory Stimuli by Controlling Macrophage Survival. Proceedings of the National Academy of Sciences USA. 2017, 114(49):12940-12945. DOI: 10.1073/pnas.1708018114;PMID: 29180421.影響因子12.779 /Q1; 被引次數：54次

87. Xiangju Yin#, Qian Wu#, Jitender Monga, Enjun Xie, Hao Wang, Shufen Wang, Huizhen Zhang, Zhan-You Wang, Tianhua Zhou, Yujun Shi, Jack Rogers, Hening Lin, Junxia Min*, Fudi Wang*. HDAC1 Governs Iron Homeostasis Independent of Histone Deacetylation in Iron-overload Murine Models. Antioxidants & Redox Signaling. 2018, 28(13):1224-1237. DOI: 10.1089/ars.2017.7161; PMID: 29113455. 影響因子：7.468 /Q1; 被引次數：18次

86. Qian Wu#, Yuanyuan Shen#, Yunlong Tao, iayu Wei, Hao Wang, Peng An, Zhuzhen Zhang, Hong Gao, Tianhua Zhou, Fudi Wang*, Junxia Min*. Hemojuvelin regulates the innate immune response to peritoneal bacterial infection in mice. Cell Discovery. 2017, 3:17028. DOI: 10.1038/celldisc.2017.28;PMID: 28815056. 影響因子38.079 /Q1; 被引次數：11次

85. Yongjuan Xin#, Hong Gao#, Jia Wang#, Yuzhen Qiang, Mustapha Umar Imam, Yang Li, Jianyao Wang, Ruochen Zhang, Huizhen Zhang, Yingying Yu, Hao Wang, Haiyang Luo, Changhe Shi, Yuming Xu, Shintaro Hojyo, Toshiyuki Fukada, Junxia Min, Fudi Wang*. Manganese transporter Slc39a14 deficiency revealed its key role in maintaining manganese homeostasis in mice. Cell Discovery. 2017, 3:17025. DOI: 10.1038/celldisc.2017.25;PMID: 28751976. 影響因子38.079 /Q1; 被引次數：96次

84. Zhidan Xia#, Jiayu Wei#, Yingniang Li, Jia Wang, Wenwen Li, Kai Wang, Xiaoli Hong, Lu Zhao, Caiyong Chen, Junxia Min*, Fudi Wang*. Zebrafish slc30a10 deficiency revealed a novel compensatory mechanism of atp2c1 in maintaining manganese homeostasis. PLoS Genetics. 2017, 13(7):e1006892. DOI: 10.1371/journal.pgen.1006892, PMID: 28692648. 影響因子6.020 /Q1; 被引次數：38次

83. Sijie Feng, Yinlong Song, Minhong Shen, Shanshan Xie, Wenjing Li, Yi Lu, Yuehong Yang, Guangshuo Ou, Jun Zhou, Fudi Wang, Wei Liu, Xiaoyi Yan*, Xin Liang*, TianhuaZhou*. Microtubule-binding protein FOR20 promotes microtubule depolymerization and cell migration. Cell Discovery. 2017, 3:17032. DOI: 10.1038/celldisc.2017.32;PMID: 28884019. 影響因子：38.079/Q1; 被引次數：13次

82. Fudi Wang*. Tackling iron deficiency in infants: galacto-oligosaccharides may be up to the task. America Journal of Clinical Nutrition. 2017, 106(4):967-968. DOI: 10.3945/ajcn.117.165878; PMID: 28877890. (Editorial ) 影響因子8.472 /Q1; 被引次數：5次【專家評論】

81. Hua Su, Fei Yang, Qiuting Wang, Qiuhong Shen, Jingtao Huang, Chao Peng, Yi Zhang, Wei Wan, Catherine C.L. Wong, Qiming Sun, Fudi Wang, Tianhua Zhou, Wei Liu*. VPS34 Acetylation Controls Its Lipid Kinase Activity and the Initiation of Canonical and Non-canonical Autophagy. Molecular Cell. 2017 , 67(6):907-921.e7. DOI: 10.1016/j.molcel.2017.07.024; PMID: 28844862. 影響因子19.328 /Q1; 被引次數：112次

80. Yi Lu#, Shanshan Xie#, Wen Zhang#, Cheng Zhang, Cheng Gao, Qiang Sun, Yuqi Cai, Zhangqi Xu, Min Xiao, Yanjun Xu, Xiao Huang, Ximei Wu, Wei Liu, Fudi Wang, Yibin Kang, Tianhua Zhou*. Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis. Cell Research. 2017, 27(12):1422-1440. DOI: 10.1038/cr.2017.107; PMID: 28829046. 影響因子46.297/Q1; 被引次數:43次

79. Hao Wang, Peng An, Enjun Xie, Qian Wu, Xuexian Fang, Hong Gao, Zhuzhen Zhang, Yuzhu Li, Xudong Wang, Jiaying Zhang, Guoli Li, Lei Yang, Wei Liu, Junxia Min* and Fudi Wang*. Characterization of Ferroptosis in Murine Models of Hemochromatosis. Hepatology. 2017, 66(2):449-465. DOI: 10.1002/hep.29117. PMID: 28195347.

Cover Story 熱點論文 封面論文：黃鼠狼給雞拜年-封面鏈接(https://aasldpubs.onlinelibrary.wiley.com/toc/15273350/2017/66/2) 影響因子17.298 /Q1; 被引次數：436次【高被引論文/封面論文】

78. Xijuan Wang#, Peng An#, Jiling Zeng, Xiaoyan Liu, Bo Wang, Xuexian Fang, Fudi Wang*, Guoping Ren*, Junxia Min*. Serum ferritin in combination with prostate-specific antigen improves predictive accuracy for prostate cancer. Oncotarget. 2017, 8(11):17862-17872. DOI:10.18632/oncotarget.14977; PMID: 28160568. 被引次數：27次

77. Mustapha Umar Imam, Shenshen Zhang, Jifei Ma, Hao Wang, Fudi Wang*. Antioxidants Mediate Both Iron Homeostasis and Oxidative Stress. Nutrients. 2017, 9(7):671. DOI: 10.3390/nu9070671; PMID: 28657578. (Invited review) 影響因子6.706 /Q1; 被引次數：196次

76. Qingqing Wang, Mustapha Umar Imam*, Yida Zhang, Fudi Wang. Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) as a Target for Concurrent Management of Diabetes and Obesity-Related Cancer. Current Pharmaceutical Design. 2017, 23(25):3677-3688. DOI: 10.2174/1381612823666170704125104; PMID: 28677503.影響因子3.310 /Q3; 被引次數：50次

75. Jiachen Zang, Hai Chen, Guanghua Zhao*, Fudi Wang, Fazheng Ren. Ferritin cage for encapsulation and delivery of bioactive nutrients: From structure, property to applications. Critical Reviews in Food Science and Nutrition.2017, 57(17):3673-3683. DOI: 10.1080/10408398.2016.1149690; PMID: 26980693. 影響因子11.208/Q1; 被引次數：73次

74. Lu Zhao, Jia Lian, Jishun Tian, Ye Shen, Zhiguang Ping, Xuexian Fang, Junxia Min, Fudi Wang*. Dietary intake of heme iron and body iron status are associated with the risk of gestational diabetes mellitus: a systematic review and meta-analysis. Asia Pacific Journal of Clinical Nutrition. 2017, 26(6):1092-1106. DOI: 10.6133/apjcn.022017.09; PMID: 28917236. 影響因子1.322/Q4; 被引次數：30次

73. Peng An#, Li Jiang#, Yu Guan, Yongmei Tian, Yanbo Shi, Jun Xue, Junxia Min, Fudi Wang*. Identification of hereditary hemochromatosis pedigrees and a novel SLC40A1 mutation in Chinese population. Blood Cells, Molecules, and Diseases. 2017, 63:34–36. DOI: 10.1016/j.bcmd.2017.01.002; PMID: 28110135. 影響因子2.372 /Q4; 被引次數：10次

72. Xuexian Fang, Kai Wang, Dan Han, Xuyan He, Jiayu Wei, Lu Zhao, Mustapha Umar Imam, Zhiguang Ping, Yusheng Li, Yuming Xu, Junxia Min and Fudi Wang*. Dietary magnesium intake and the risk of cardiovascular disease, type 2 diabetes, and all-cause mortality: a dose–response meta-analysis of prospective cohort studies. BMC Medicine. 2016, 14(1):210. PMID: 27927203. 影響因子11.150/Q1; 被引次數：264次

71. Igor T, Hilgendorf I, Nairz M, Tymoszuk P, Haschka D, Asshoff M, He S, Gerhardt L, Holderried T, Seifert M, Sopper S, Fenn A, Anzai A, Rattik S, McAlpine C, Theurl M, Wieghofer P, Iwamoto Y, Weber G, Harder N, Chousterman B, Arvedson T, McKee M, Fudi Wang, Lutz O, Rezoagli E, Babitt JL, Berra L, Prinz M, Nahrendorf M, Weiss G, Weissleder R, Lin H, Swirski F. On-demand erythrocyte disposal and iron recycling requires transient macrophages in the liver. Nature Medicine. 2016, 22(8):945-51. DOI: 10.1038/nm.4146; PMID: 27428900. 影響因子87.241/Q1; 被引次數：368次

70 Yi Cai, Qianting Yang, Mingfeng Liao, Hao Wang, Chi Zhang, Subhalaxmi Nambi, Wenfei Wang, Mingxia Zhang, Junying Wu, Guofang Deng, Qunyi Deng, Haiying Liu, Boping Zhou, Qi Jin, Carl G Feng, Christopher Sassetti,Fudi Wang*, Xinchun Chen*. xCT increases tuberculosis susceptibility by regulating antimicrobial function and inflammation. Oncotarget. 2016, 7(21):31001-13. DOI: 10.18632/oncotarget.9052; PMID: 27129162. 被引次數：31次

69. Wendai Bao, Yao Fan, Yuezhen Deng, Lingyun Long, Jingjing Wang, Dongxian Guan, Zhenyu Qian, Peng An, Yuanyuan Feng, Zhiying He, Xiaofan Wang, H. Phillip Koeffler, Ronggui Hu, Jianshe Wang, Xin Wang, Fudi Wang, Jingjing Li, Dong Xie*. Iron overload in hereditary tyrosinemia type 1 induces liver injury through the Sp1/Tfr2/hepcidin axis. Journal of Hepatology. 2016, 65:137–45. DOI: 10.1016/j.jhep.2016.03.007; PMID: 27013087. 影響因子30.083 /Q1; 被引次數：19次

68. Lei R, Zhang K, Liu K, Shao X, Ding Z, Wang F(Fudi Wang), Hong Y, Zhu M, Li H, Li H*. Transferrin receptor facilitates TGF-β and BMP signaling activation to control craniofacial morphogenesis. Cell Death & Disease. 2016, 7(6):e2282. DOI: 10.1038/cddis.2016.170; PMID: 27362800. 影響因子9.685 /Q1; 被引次數：21次

67. Shengli Zhang, Jiachen Zang, Wenming Wang, Hai Chen, Xiaorong Zhang, Fudi Wang, Hongfei Wang*, and Guanghua Zhao*. Conversion of the Native 24-mer Ferritin Nanocage into Its Non-Native 16-mer Analogue by Insertion of Extra Amino Acid Residues. Angew Chem Int Ed Engl. 2016, 55(52):16064-16070. DOI: 10.1002/anie.201609517; PMID: 27885765. 影響因子16.823/Q1; 被引次數：35次

66. Jiachen Zang, Changan Li, Kai Zhou, Haisheng Dong, Bin Chen, Fudi Wang, Guanghua Zhao. Nanomolar Hg2+ Detection Using β-Lactoglobulin-Stabilized Fluorescent Gold Nanoclusters in Beverage and Biological Media.Analytical chemistry. 2016, 88(20):10275-10283. DOI: 10.1021/acs.analchem.6b03011; PMID: 27680745. 影響因子8.008/Q1; 被引次數：85次

65. Ke Liu, Run Lei, Qiong Li, Xinxin Wang, Qian Wu, Peng An, Jianchao Zhang, Minyan Zhu, Zhiheng Xu, Yang Hong, Fudi Wang, Ying Shen, Hongchang Li, Huashun Li*. Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Scientific Reports. 2016, 6:21019. DOI: 10.1038/srep21019; PMID: 26880306. 影響因子4.996 /Q2; 被引次數：31次

64. Mingdao Mu, Peng An, Qian Wu, Xiaoyun Shen, Dandan Shao, Hao Wang, Yingqi Zhang, Shenshen Zhang, Hui Yao, Junxia Min, Fudi Wang*. The dietary flavonoid myricetin regulates iron homeostasis by suppressing hepcidin expression. Journal Nutrition Biochemistry. 2016, 30: 53-61. DOI: 10.1016/j.jnutbio.2015.10.015;PMID: 27012621. 影響因子6.117 /Q1; 被引次數：29次

63. Xianlei Cai#, Chen Wang#, Wanqi Yu, Wenjie Fan, Shan Wang, Ning Shen, Pengcheng Wu, Xiuyang Li*, Fudi Wang*. Selenium Exposure and Cancer Risk: an Updated Meta-analysis and Meta-regression. Scientific Reports.2016, 6:19213. DOI: 10.1038/srep19213; PMID: 26786590. 影響因子4.996/Q2; 被引次數：215次

62. Li Jiang Li, Xuyan He, Jiayu Wei, Xinhui Wang, Fudi Wang*. Advances of phytochemicals in mediating micronutrients metabolisms. Chinese Bulletin of Life Sciences. 2015, 27(8). DOI: 10.13376/j.cbls/2015141. 蔣麗，何旭豔，魏家璵，王鑫慧，王福俤*. 植物化合物調控微量營養素穩態代謝的研究進展. 生命科學. 被引次數：0次

61. Fudi Wang*. Trace element research in China: Present and future. Chinese Bulletin of Life Sciences. 2012, 24(8): 713-730. DOI:10.13376/j.cbls/2012.08.020. 王福俤*. 中國生物微量元素研究的現狀與展望. 生命科學. 被引次數：0次

60. Wenjie Chen*， Fudi Wang*.The critical role of Hemojuvelin in iron homeostasis. Chinese Bulletin of Life Sciences. 2012,24(08):753-758.DOI:10.13376/j.cbls/2012.08.003. 陳文傑*，王福俤*. Hemojuvelin在鐵穩態平衡中的關鍵作用. 生命科學. 被引次數：0次

59. Yu Guan， Peng An， Zhuzhen Zhang，Fudi Wang*. Advances in pathophysiology， diagnosis and management of hereditary hemochromatosis. Chinese Bulletin of Life Sciences. 2012,24(08):775-784.DOI:10.13376/j.cbls/2012.08.005. 管宇，安鵬，張竹珍，王福俤*. 血色病的臨牀與基礎研究進展. 生命科學. 被引次數：0次

58. Jia Shen*， Fudi Wang， Ronggui Hu*. Recent advance on crosstalk between iron metabolism and cellular protein ubiquitylation and degradation. Chinese Bulletin of Life Sciences. 2012,24(08):785-793.DOI:10.13376/j.cbls/2012.08.006. 沈佳*，王福俤， 胡榮貴*. 鐵代謝與蛋白質泛素化-降解調控研究進展. 生命科學. 被引次數：0次

57. Yijun Liao， Yanbo Shi， Zhiqin Zhou， Fudi Wang*. Advances in the study of iron metabolism and pathogenesis of type 2 diabetes. Chinese Bulletin of Life Sciences. 2012, 24(08):794-802. DOI:10.13376/j.cbls/2012.08.007. 廖益均，石彥波，周志欽，王福俤*.鐵與2型糖尿病發病的最新進展. 生命科學. 被引次數：0次

56. Xin Guo， Fudi Wang*.Mouse models of mammalian iron metabolism. Chinese Bulletin of Life Sciences.郭鑫,王福俤.小鼠模型在鐵代謝研究中的應用. 生命科學,2012,24(08):917-926. DOI: 10.13376/j.cbls/2012.08.019. 被引次數：0次

55. Guang Yan， Yanbo Shi， Zeli Peng， Fudi Wang*. Zebrafish as a vertebrate model for trace element metabolism studies. Chinese Bulletin of Life Sciences. 2012, 24(8): 939-947. DOI:10.13376/j.cbls/2012.08.024.顏廣，石彥波，彭澤麗，王福俤*.模式生物斑馬魚在微量元素代謝研究中的應用. 生命科學. 被引次數：0次

54. Xianlei Cai, Chen Wang, Shan Wang, Gaoyang Cao, Chao Jin, Jiawei Yu, Xiuyang Li, Jing Yan, Fudi Wang, Wei Yu, Fang Ding. Carbohydrate Intake, Glycemic Index, Glycemic Load, and Stroke: A Meta-analysis of Prospective Cohort Studies. Asia Pac J Public Health. 2015, 27(5):486-96. DOI: 10.1177/1010539514566742; PMID: 25593213. 影響因子2.27/Q3; 被引次數：47次

53. Jia Shen, Xiangpeng Sheng, ZeNan Chang, Qian Wu, Dong Xie, Fudi Wang, and Ronggui Hu*. The heme-p53 interaction: Linking iron metabolism to p53 signaling and tumorigenesis. Molecular & Cellular Oncology. 2015, 3:e965642–2. DOI: 10.4161/23723548.2014.965642; PMID: 27308524. 被引次數：14次

52. Peng An, Hao Wang, Qian Wu, Xin Guo, Aimin Wu, Zhou Zhang, Di Zhang, Xiaochen Xu, Qianyun Mao, Xiaoyun Shen, Lihong Zhang, Zhiqi Xiong, Lin He, Yun Liu, Junxia Min*, Daizhan Zhou*, Fudi Wang*. Elevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk. Scientific Reports. 2015, 5:13106. DOI: 10.1038/srep13106; PMID: 26290281. 影響因子4.996/Q3; 被引次數：12次

51. Qian Wu#, Hao Wang#, Peng An, Yunlong Tao, Jiali Deng, Zhuzhen Zhang, Yuanyuan Shen, Caiyong Chen, Junxia Min *, Fudi Wang*. HJV and HFE Play Distinct Roles in Regulating Hepcidin. Antioxidants & Redox Signaling.2015, 22:1325–1336.DOI: 10.1089/ars.2013.5819; PMID: 25608116. 影響因子7.468 /Q1; 被引次數：20次

50. Xuexian Fang, Jiayu Wei, Xuyan He, Peng An, Hao Wang, Li Jiang, Dandan Shao, Han Liang, Yi Li, Fudi Wang*, Junxia Min*. Landscape of dietary factors associated with risk of gastric cancer: A systematic review and dose-response meta-analysis of prospective cohort studies. European Journal of Cancer. 2015, 51(18):2820-32. DOI: 10.1016/j.ejca.2015.09.010; PMID: 26589974. 影響因子10.002 /Q1; 被引次數：263次

49. Xuexian Fang, Hao Wang, Peng An, Junxia Min, Fudi Wang*. Cardiomyocyte-specific deletion of ferroportin using MCK-Cre has no apparent effect on cardiac iron homeostasis. International Journal of Cardiology. 2015, 201:90-2. DOI: 10.1016/j.ijcard.2015.07.089; PMID: 26292272. 影響因子4.039/Q2; 被引次數：14次

48. Xuexian Fang, Peng An, Hao Wang, Xinhui Wang, Xiaoyun Shen, Xiuyang Li, Junxia Min, Simin Liu, Fudi Wang*. Dietary intake of heme iron and risk of cardiovascular disease: A dose-response meta-analysis of prospective cohort studies. Nutrition, Metabolism & Cardiovascular Diseases. 2015, 25(1): 24-35. DOI: 10.1016/j.numecd.2014.09.002; PMID: 25439662. 影響因子4.666/Q2; 被引次數：93次

47. Zhen Liu#, Yu Yu#, Xiaohong Li, Aimin Wu, Mingdao Mu, Nana Li, Ying Deng, Shengli Li, Yuan Lin, Xinlin Chen, Fudi Wang*, Jun Zhu*. Maternal lead exposure and risk of congenital heart defects occurrence in offspring. Reproductive Toxicology. 2015, 51:1-6. DOI: 10.1016/j.reprotox.2014.11.002; PMID: 25462788. 影響因子3.421/Q2; 被引次數：56次

46. Xinhui Wang, Xuexian Fang and Fudi Wang*. Pleiotropic actions of iron balance in diabetes mellitus. Reviews in Endocrine & Metabolic Disorders. 2015, 16(1):15-23 (Review). DOI: 10.1007/s11154-014-9303-y; PMID: 25520048. 影響因子9.306/Q1; 被引次數：42次

45. Zhao L, Zhang X, Shen Y, Fang X, Wang Y, and Wang F*(Fudi Wang*). Obesity and iron deficiency: a quantitative meta-analysis. Obesity Reviews. 2015, 16(12):1081-93. DOI: 10.1111/obr.12323. PMID: 26395622. 影響因子10.867/Q1; 被引次數：244次

44. Yi Qian, Chunyang Yin, Yue Chen, Shuping Zhang, Li Jiang, Fudi Wang, Meirong Zhao, Sijin Liu*. Estrogen contributes to regulating iron metabolism through governing ferroportin signaling via an estrogen response element. Cellular Signaling. 2015, 27:934–942. DOI: 10.1016/j.cellsig.2015.01.017; PMID: 25660146. 影響因子4.850 /Q2; 被引次數：49次

43. Tao Huang#, Liang Lan#, Xuexian Fang, Peng An, Junxia Min, Fudi Wang*. Promises and Challenges of BigData Computing in Health Sciences. Big Data Research. 2015, 2(1): 2-11. DOI: 10.1016/j.bdr.2015.02.002. 影響因子3.739 /Q4; 被引次數：256次

42. Lu Zhao, Zhidan Xia, Fudi Wang*. Zebrafish in the sea of mineral (iron, zinc, and copper) metabolism. Frontiers in Pharmacology. 2014; 5:33–33. DOI: 10.3389/fphar.2014.00033; PMID: 24639652. 響因子5.988/Q1; 被引次數：101次

41. Zhuzhen Zhang, Xin Guo, Carolina Herrera, Yunlong Tao, Qian Wu, Aimin Wu, Hao Wang, Thomas B Bartnikas, Zhang Z, Guo X, Herrera C, Tao Y, Wu Q, Wu A, Wang H, Bartnikas TB, Fudi Wang*. Bmp6 expression can be regulated independently of liver iron in mice. PLoS One. 2014, 9(1):e84906. DOI: 10.1371/journal.pone.0084906; PMID: 24454764. 影響因子3.752 /Q2; 被引次數：12次

40. Xinggang Wu, Yang Wang, Qian Wu, Waihang Cheng, Wenjing Liu, Yueshui Zhao, Claire Mayeur, Paul J Schmidt, Paul B Yu, Fudi Wang, Yin Xia*. HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression. Blood. 2014, 124(8):1335-43. DOI: 10.1182/blood-2014-01-552281;PMID: 24904118. 影響因子25.476 /Q1; 被引次數：130次【專家亮點點評】

39. Yunlong Tao, Qian Wu, Xin Guo, Zhuzhen Zhang, Shen, Yuanyuan Shen, Fudi Wang*. MBD5 regulates iron metabolism via methylation-independent genomic targeting of Fth1 through KAT2A in mice. British Journal of Haematology. 2014, 166(2):279-91. DOI: 10.1111/bjh.12863; PMID: 24750026. 影響因子8.615 /Q1; 被引次數：33次

38. Yunlong Tao, Yu Wang, Jack T. Rogers, Fudi Wang*. Perturbed iron distribution in Alzheimer's disease serum, cerebrospinal fluid, and selected brain regions: a systematic review and meta-analysis. Journal of Alzheimer's Disease. 2014, 42(2):679-90. DOI: 10.3233/JAD-140396; PMID: 24916541.影響因子4.160 /Q2; 被引次數：132次

37. Jia Shen, Xiangpeng Sheng, Zenan Chang, Qian Wu, Sheng Wang, Zongliang Xuan, Dan Li, Yalan Wu, Yongjia Shang, Xiangtao Kong, Long Yu, Lin Li, Kangchen Ruan, Hongyu Hu, Ying Huang, Lijian Hui, Dong Xie, Fudi Wang, Ronggui Hu*. Iron metabolism regulates p53 signaling through direct heme-p53 interaction and modulation of p53 localization, stability, and function. Cell Reports. 2014, 7(1):180-93. DOI: 10.1016/j.celrep.2014.02.042;PMID: 24685134. 影響因子9.995 /Q1; 被引次數：206次

36. Mingdao Mu, Aimin Wu, Peng An, Xiaoli Du, Qian Wu, Xiaoyun Shen, Fudi Wang*. Black soyabean seed coat extract regulates iron metabolism by inhibiting the expression of hepcidin. British Journal of Nutrition. 2014, 111(7):1181-9. DOI:10.1017/S0007114513004005; PMID: 24387766. 影響因子4.125/Q3; 被引次數：22次

35. Beben Benyamin, Tonu Esko, Janina S Ried, Aparna Radhakrishnan, Sita H Vermeulen, Michela Traglia, Martin Gögele, Denise Anderson, Linda Broer, Clara Podmore, Jian'an Luan, Zoltan Kutalik, Serena Sanna, Peter van der Meer, Toshiko Tanaka, Fudi Wang, Harm-Jan Westra, Lude Franke, Evelin Mihailov, Lili Milani, Jonas Hälldin, Juliane Winkelmann, Thomas Meitinger, Joachim Thiery, Annette Peters, Melanie Waldenberger, Augusto Rendon, Jennifer Jolley, Jennifer Sambrook, Lambertus A Kiemeney, Fred C Sweep, Cinzia F Sala, Christine Schwienbacher, Irene Pichler, Jennie Hui, Ayse Demirkan, Aaron Isaacs, Najaf Amin, Maristella Steri, Gérard Waeber, Niek Verweij, Joseph E Powell, Dale R Nyholt, Andrew C Heath, Pamela A F Madden, Peter M Visscher, Margaret J Wright, Grant W Montgomery, Nicholas G Martin, Dena Hernandez, Stefania Bandinelli, Pim van der Harst, Manuela Uda, Peter Vollenweider, Robert A Scott, Claudia Langenberg, Nicholas J Wareham, InterAct Consortium; Cornelia van Duijn, John Beilby, Peter P Pramstaller, Andrew A Hicks, Willem H Ouwehand, Konrad Oexle, Christian Gieger, Andres Metspalu, Clara Camaschella, Daniela Toniolo, Dorine W Swinkels, John B Whitfield. Novel loci affecting iron homeostasis and their effects in individuals at risk for hemochromatosis. Nature Communications. 2014, 5:4926. DOI: 10.1038/ncomms5926; PMID: 25352340. 影響因子17.694 /Q1; 被引次數：232次

34. Yu Yu, Aimin Wu, Zhuzhen Zhang, Guang Yan, Fan Zhang, Lihong Zhang, Xiaoyun Shen, Ronggui Hu, Yan Zhang*, Keying Zhang*, Fudi Wang*. Characterization of the GufA subfamily member SLC39A11/Zip11 as a zinc transporter. Journal of Nutritional Biochemistry. 2013, 24(10):1697-708. DOI: 10.1016/j.jnutbio.2013.02.010; PMID: 23643525. 影響因子6.117 /Q1; 被引次數：74次

33. Xin Guo, Daizhan Zhou, Peng An, Qian Wu, Hao Wang, Aimin Wu, Mingdao Mu, Di Zhang, Zhou Zhang, Hui Wang, Lin He, Yun Liu*, Fudi Wang*. Associations between serum hepcidin, ferritin and Hb concentrations and type 2 diabetes risks in a Han Chinese population. British Journal of Nutrition. 2013, 110(12):2180-5. DOI: 10.1017/S0007114513001827; PMID: 23742704. 影響因子4.125/Q3; 被引次數：54次

32. Xin Guo, Zhuzhen Zhang, Fan Zhang, Yunlong Tao, Peng An, Qian Wu, Chia-Yu Wang, Mitchell D Knutson, Fudi Wang*. Fine-mapping and genetic analysis of the loci affecting hepatic iron overload in mice. PLoS One. 2013, 8(5):e63280.DOI: 10.1371/journal.pone.0063280;PMID: 23675470. 影響因子3.752 /Q2; 被引次數：2次

31. Yu Guan, Peng An, Zhuzhen Zhang, Fan Zhang, Yu Yu, Qian Wu, Yanbo Shi, Xin Guo, Yunlong Tao, Fudi Wang*. Screening identifies the Chinese medicinal plant Caulis Spatholobi as an effective HAMP expression inhibitor. Journal of Nutrition. 2013, 143(7):1061-6. DOI: 10.3945/jn.113.174201; PMID: 23700338. 影響因子4.687 /Q2; 被引次數：30次

30. Peizhan Chen, Mian Li, Xiaoli Gu, Yanling Liu, Xiaoguang Li, Chenglin Li, Yuan Wang, Dong Xie, Fudi Wang, Chen Yu, Jingquan Li, Xinlei Chen, Ruiai Chu, Jianmin Zhu, Zhouluo Ou, Hui Wang*. Higher blood 25(OH)D level may reduce the breast cancer risk: evidence from a Chinese population based case-control study and meta-analysis of the observational studies. PLoS One. 2013, 8(1):e49312. DOI: 10.1371/journal.pone.0049312; PMID: 23382798. 影響因子3.752/Q2; 被引次數：95次

29. Zhuzhen Zhang, Fan Zhang, Xin Guo, Peng An, Yunlong Tao, Fudi Wang*. Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice. Hepatology. 2012, 56(3):961-71.DOI: 10.1002/hep.25746; PMID: 22473803. 影響因子17.298 /Q1; 被引次數：93次

28. Fan Zhang, Yunlong Tao, Zhuzhen Zhang, Xin Guo, Peng An, Yuanyuan Shen, Qian Wu, Yu Yu, Fudi Wang*. Metalloreductase Steap3 coordinates the regulation of iron homeostasis and inflammatory responses. Haematologica. 2012, 97(12):1826-35. DOI: 10.3324/haematol.2012.063974; PMID: 22689674. 影響因子11.047 /Q1; 被引次數：100次

27. Guang Yan, Yuchao Zhang, Junlei Yu, Yu Yu, Fan Zhang, Zhuzhen Zhang, Aimin Wu, Xianghua Yan, Yi Zhou, Fudi Wang*. Slc39a7/zip7 plays a critical role in development and zinc homeostasis in zebrafish. PLoS One. 2012, 7(8):e42939.DOI: 10.1371/journal.pone.0042939; PMID: 22912764. 影響因子3.752/Q2; 被引次數：47次

26. Liang Sun, Yu Yu, Tao Huang, Peng An, Danxia Yu, Zhijie Yu, Huaixing Li, Hongguang Sheng, Lu Cai, Jun Xue, Miao Jing, Yixue Li*, Xu Lin*, Fudi Wang*. Associations between ionomic profile and metabolic abnormalities in human population. PLoS One. 2012, 7(6):e38845. DOI: 10.1371/journal.pone.0038845; PMID: 22719963. 影響因子3.752/Q2; 被引次數：86次

25. Jeeyon Jeong, Joel M Walker, Fudi Wang, J Genevieve Park, Amy E Palmer, Cecilia Giunta, Marianne Rohrbach, Beat Steinmann, David J Eide*. Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome. Proceedings of the National Academy of Sciences USA. 2012, 109(51): E3530-8. DOI: 10.1073/pnas.1211775110; PMID: 23213233. 影響因子12.779 /Q1; 被引次數：114次

24. Wei Gan, Yu Guan, Qian Wu, Peng An, Jingwen Zhu, Ling Lu, Li Jing, Yu Yu, Sheng Ruan, Dong Xie, Maria Makrides, Robert A Gibson, Gregory J Anderson, Huaixing Li*, Xu Lin*, Fudi Wang*. Association of TMPRSS6 polymorphisms with ferritin, hemoglobin, and type 2 diabetes risk in a Chinese Han population. American Journal of Clinical Nutrition. 2012, 95(3):626-32.DOI: 10.3945/ajcn.111.025684; PMID: 22301935. 影響因子8.472 /Q1; 被引次數：81次

23. Gregory J Anderson* and Fudi Wang. Essential but toxic: controlling the flux of iron in the body. Clinical and Experimental Pharmacology and Physiology. 2012, 39(8):719-24. DOI: 10.1111/j.1440-1681.2011.05661.x;PMID: 22211782. 影響因子2.963 /Q3; 被引次數：51次

22. Peng An, Qian Wu, Hao Wang, Yu Guan, Mingdao Mu, Yijun Liao, Daizhan Zhou, Pengkun Song, Chunrong Wang, Liping Meng, Qingqing Man, Lixiang Li, Jian Zhang, Fudi Wang*. TMPRSS6, but not TF, TFR2 or BMP2 variants are associated with increased risk of iron-deficiency anemia. Human Molecular Genetics. 2012, 21(9): 2124-31.DOI: 10.1093/hmg/dds028; PMID: 22323359. 影響因子5.121 /Q1; 被引次數：119次

21. Zhuzhen Zhang, Fan Zhang, Peng An, Xin Guo, Yuanyuan Shen, Yunlong Tao, Qian Wu, Yuchao Zhang, Yu Yu, Bo Ning, Guangjun Nie, Mitchell D Knutson, Gregory J Anderson, Fudi Wang*. Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood. 2011, 118(7):1912-22. DOI: 10.1182/blood-2011-01-330324 ; PMID: 21705499. 影響因子25.476 /Q1; 被引次數：221次

20. Qian Ba, Miao Hao, He Huang, Junmei Hou, Shichao Ge, Zhuzhen Zhang, Jun Yin, Ruiai Chu, Hualiang Jiang, Fudi Wang, Kaixian Chen, Hong Liu, Hui Wang*. Iron deprivation suppresses hepatocellular carcinoma growth in experimental studies. Clinical Cancer Research. 2011, 17(24):7625-33. DOI: 10.1158/1078-0432.CCR-10-3099;PMID: 22052937. 影響因子13.801 /Q1; 被引次數:71次

19. Eric Mills, Xianping Dong, Fudi Wang, Haoxing Xu*. Mechanisms of brain iron transport: insight into neurodegeneration and CNS disorders. Future Medicinal Chemistry. 2010, 2(1):51-64. DOI: 10.4155/fmc.09.140; PMID: 20161623. 影響因子4.767 /Q2; 被引次數：322次

18. Liang Guo, Louis A Lichten, Moon-Suhn Ryu, Juan P Liuzzi, Fudi Wang, Robert J Cousins*. STAT5-glucocorticoid receptor interaction and MTF-1 regulate the expression of ZnT2 (Slc30a2) in pancreatic acinar cells. Proceedings of the National Academy of Sciences USA. 2010, 107(7):2818-23. DOI: 10.1073/pnas.0914941107; PMID: 20133611. 影響因子12.779 /Q1; 被引次數：137次

17. Yuxiong Feng, Jiangsha Zhao, Jingjing Li, Tao Wang, Shuqun Cheng, Yunfei Yuan, Fudi Wang, Xiao-Fan Wang, Dong Xie*. Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway. Hepatology. 2010, 51(2):535-44. DOI: 10.1002/hep.23313; PMID: 19918976. 影響因子17.298 /Q1; 被引次數：59次

16. Peizhan Chen, Pingting Hu, Dong Xie, Ying Qin, Fudi Wang, Wang H*. Meta-analysis of vitamin D, calcium and the prevention of breast cancer. Breast Cancer Research and Treatment. 2010, 121(2):469-77. DOI: 10.1007/s10549-009-0593-9; PMID: 19851861. 影響因子4.624/Q2; 被引次數：445次

15. Xianping Dong, Xiping Cheng, Eric Mills, Markus Delling, Fudi Wang, Tino Kurz, Haoxing Xu*. The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel. Nature. 2008;455(7215):992-6. DOI: 10.1038/nature07311;PMID: 18794901. 影響因子69.504 /Q1; 被引次數：548次

14. Fudi Wang, Prasad N Paradkar, Angel O Custodio, Diane McVey Ward, Mark D Fleming, Dean Campagna, Kristina A Roberts, Victor Boyartchuk, William F Dietrich, Jerry Kaplan, Nancy C Andrews. Genetic variation in Mon1a affects protein trafficking and modifies macrophage iron loading in mice. Nature Genetics. 2007, 39(8):1025-32. DOI: 10.1038/ng2059; PMID: 17632513. 影響因子41.307 /Q1; 被引次數：82次

13. Fudi Wang, Adam P Lothrop, Nicholas G James, Tanya A M Griffiths, Lisa A Lambert, Rachael Leverence, Igor A Kaltashov, Nancy C Andrews, Ross T A MacGillivray, Anne B Mason*. A novel murine protein with no effect on iron homoeostasis is homologous with transferrin and is the putative inhibitor of carbonic anhydrase. Biochemical Journal. 2007, 406(1):85-95. DOI: 10.1042/BJ20070384; PMID: 17511619. 影響因子3.766 /Q3; 被引次數：16次

12. Xiaoqing Mao, Byung-Eun Kim, Fudi Wang, David J Eide, Michael J Petris*. A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity. Journal of Biological Chemistry. 2007, 282(10):6992-7000. DOI: 10.1074/jbc.M610552200; PMID: 17202136. 影響因子5.486 /Q2; 被引次數：201次

11. Sijin Liu, Rajasekhar N V S Suragani, Fudi Wang, Anping Han, Wanting Zhao, Nancy C Andrews, Jane-Jane Chen*. The function of heme-regulated eIF2α kinase in murine iron homeostasis and macrophage maturation. Journal of Clinical Investigation. 2007, 117(11):3296-305. DOI: 10.1172/JCI32084; PMID: 17932563. 影響因子19.456 /Q1; 被引次數：103次

10. Wendy R Mathews, Fudi Wang, David J Eide, Mark Van Doren*. Drosophila fear of intimacy encodes a Zrt/IRT-like protein (ZIP) family zinc transporter functionally related to mammalian ZIP proteins. Journal of Biological Chemistry. 2005, 280(1):787-95. DOI: 10.1074/jbc.M411308200; PMID: 15509557. 影響因子5.486 /Q2; 被引次數：74次

9. Jackie E Lim, Ou Jin, Carolyn Bennett, Kelly Morgan, Fudi Wang, Cameron C Trenor 3rd, Mark D Fleming, Nancy C Andrews*. A mutation in Sec15l1 causes anemia in hemoglobin deficit (hbd) mice. Nature Genetics. 2005, 37(11):1270-3. DOI: 10.1038/ng1659; PMID: 17632513. 影響因子41.307/Q1; 被引次數：116次

8. Fudi Wang, Byung-Eun Kim, Michael J Petris, David J Eide*. The mammalian Zip5 protein is a zinc transporter that localizes to the basolateral surface of polarized cells. Journal of Biological Chemistry. 2004, 279(49):51433-41.DOI: 10.1074/jbc.M408361200; PMID: 15322118. 影響因子5.486 /Q2; 被引次數：196次

7. Fudi Wang, Byung-Eun Kim, Jodi Dufner-Beattie, Michael J Petris, Glen Andrews, David J Eide*. Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter. Human Molecular Genetics. 2004, 13(5):563-71. DOI: 10.1093/hmg/ddh049;PMID: 14709598. 影響因子5.121 /Q1; 被引次數：193次

6. Fudi Wang, Jodi Dufner-Beattie, Byung-Eun Kim, Michael J Petris, Glen Andrews, David J Eide*. Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters. Journal of Biological Chemistry. 2004, 279(23):24631-9. DOI: 10.1074/jbc.M400680200. PMID: 15054103. 影響因子5.486/Q2; 被引次數：164次

5. Byung-Eun Kim, Fudi Wang, Jodi Dufner-Beattie, Glen K Andrews, David J Eide, Michael J Petris*. Zn2+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane. Journal of Biological Chemistry. 2004, 279(6):4523-30. DOI: 10.1074/jbc.M310799200; PMID: 14612438. 影響因子5.486/Q2; 被引次數：190次

4. Charissa D Ellis, Fudi Wang, Colin W MacDiarmid, Suzanne Clark, Thomas Lyons, David J Eide*. Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function. Journal of Cell Biology. 2004, 166(3):325-35. DOI: 10.1083/jcb.200401157; PMID: 15277543. 影響因子8.077 /Q1; 被引次數：227次

3. Jodi Dufner-Beattie, Fudi Wang, Yien-Ming Kuo, Jane Gitschier, David Eide, Glen K Andrews*. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. Journal of Biological Chemistry. 2003, 278(35):33474-81. DOI: 10.1074/jbc.M305000200; PMID: 12801924. 影響因子5.486/Q2; 被引：344次

2. Jodi Dufner-Beattie, S Joshua Langmade, Fudi Wang, David Eide, Glen K Andrews*. Structure, function, and regulation of a subfamily of mouse zinc transporter genes. Journal of Biological Chemistry. 2003, 278(50):50142-50. DOI: 10.1074/jbc.M304163200; PMID: 14525987. 影響因子5.486/Q2; 被引次數：212次

1. Fudi Wang, Wei Bian, Lingwei Kong, Faji Zhao, Junsheng Guo, Naihe Jing*. Maternal zinc deficiency impairs brain nestin expression in prenatal and postnatal mice. Cell Research. 2001, 11(2):135-41. DOI: 10.1038/sj.cr.7290078; PMID: 11453545. 影響因子46.297 /Q1; 被引次數：70次