王昊陽

1996/09–2000/06，中國藥科大學，藥學院，藥物分析專業，本科

2000/09–2003/06，中國藥科大學與上海有機化學研究所聯合培養，碩士

2003/09–2006/06，中國科學院上海有機化學研究所，博士

2006/07–2008/07，德國奧爾登堡大學，化學系，博士後

2008/09–2017/02，中國科學院上海有機化學研究所，副研究員

2017/03–至今，中國科學院上海有機化學研究所，公共技術服務中心質譜組，課題組長 ^[2] 

主要從事有機質譜學研究，致力於開發質譜學新技術解決有機化學中有挑戰的難題，並基於有機化學基本理論發展新的質譜學方法。在新型質譜離子源研發，反應機理與氣相化學研究，食品安全和藥物分析的質譜快檢技術開發等方面取得了一些科研成果。 ^[2] 

近年代表性科研論文

1. Meng-Xi Wu, Hao-Yang Wang*, Jun-Ting Zhang, Yin-Long Guo*. Multifunctional Carbon Fiber Ionization Mass Spectrometry, Anal. Chem. 2016, 88(19), 9547−9553.

2.Jun-Ting Zhang, Hao-Yang Wang*, Xiang Zhang, Fang Zhang, Yin-Long Guo*. Study of short-lived and early reaction intermediates in organocatalytic asymmetric amination reactions by ion-mobility mass spectrometry. Catal. Sci. Technol. 2016, 6, 6637–6643.

3.Qilun Liu, Zheliang Yuan, Hao-Yang Wang*, Yang Li, Yichen Wu, Tao Xu, Xuebing Leng, Pinhong Chen, Yin-long Guo, Zhenyang Lin*, Guosheng Liu*. Abnormal Mesoionic Carbene Silver Complex: Synthesis, Reactivity and Mechanistic Insight on Oxidative Fluorination. ACS Catalysis, 2015, 5(11), 6732–6737.

4.Zheliang Yuan, Hao-Yang Wang, Xin Mu, Pinhong Chen, Yin-long Guo, Guosheng Liu*. Highly Selective Pd-Catalyzed Intermolecular Fluorosulfonylation of Styrenes. J. Am. Chem. Soc. 2015, 137(7), 2468–2471.

5.Xiao-Pan Liu, Hao-Yang Wang*, Jun-Ting Zhang, Meng-Xi Wu, Wan-Shu Qi, Hui Zhu, Yin-Long Guo*. Direct and Convenient Mass Spectrometry Sampling with Ambient Flame Ionization. Scientific Reports, 2015, 5, 16893.

6.Hao-Yang Wang*, Jun-Ting Zhang, Shu-Sheng Zhang, Yin-Long Guo*. The remarkable role of solvent in reaction mechanism studies by electrospray mass spectrometry. Org. Chem. Front., 2015, 2, 990–994.

7.Hao-Yang Wang*, Jun-Ting Zhang, Shi-Hao Sun, Shu-Sheng Zhang, Fang Zhang, Hui Zhu, Yin-Long Guo*. Study on the Accelerated Gutknecht Self-Cyclocondensation of Amino-sugars at Atmospheric Pressure Chemical Ionization Condition. RSC Advances, 2015, 5, 105079–105083.

8.Youai Qiu, Jing Zhou, Junzhao Li, Chunling Fu, Yin-long Guo, Haoyang Wang*, Shengming Ma*. Asymmetric Construction of Six-Membered Rings by Cyclization of Allenes with Dinuclear Gold Catalysis. Chem. Eur. J. 2015, 21(45):15939–15943.

9.Jun-Ting Zhang, Hao-Yang Wang*, Wei Zhu, Ting-Ting Cai, Yin-Long Guo*. Solvent-assisted Electrospray Ionization for Direct Analysis of Various Compounds (complex) from Low/non-polar Solvents and Eluents. Anal. Chem. 2014, 86(18), 8937–8942.

10.Haoyang Wang*, Zhixiong Zhao, Yinlong Guo*. Chemical and biochemical applications of MALDI TOF-MS based on analyzing the small organic compounds. in: Applications of MALDI-TOF Spectroscopy. Zongwei Cai, Shuying Liu (Eds.) Top. Curr. Chem. 2013, 331, 165–192.

11.Hao-Yang Wang*, Ying Gao, Fang Zhang, Chong-Tian Yu, Chu Xu, Yin-Long Guo*. Mass spectrometric study of the gas-phase difluorocarbene expulsion of polyfluorophenyl cations via F-atom migration. J. Am. Soc. Mass Spectrom. 2013, 24(12), 1919–1926.

12.Hao-Yang Wang*, Zhang Xiang, Guo-Sheng Liu, Yin-Long Guo*. Study of the gas phase intramolecular aryltrifluoromethylation of phenyl(trifluoromethyl) iodonium by ESI-MS/MS. J. Am. Soc. Mass Spectrom. 2013, 24(5), 761–767.

13.Hao-Yang Wang, Wai-Leung Yim, Yin-Long Guo, Jürgen O. Metzger*. ESI-MS studies and calculations on second-generation Grubbs and Hoveyda-Grubbs ruthenium olefin metathesis catalysts. Organometallics 2012, 31(5), 1627–1634.

14.Xin Mu, Tao Wu, Hao-yang Wang, Yin-long Guo, Guosheng Liu*. Palladium-catalyzed oxidative aryltrifluoromethylation of activated alkenes at room temperature. J. Am. Chem. Soc. 2012, 134 (2), 878–881.

15.Hao-Yang Wang, Wai-Leung Yim, Thorsten Klüner, Jürgen O. Metzger*. ESIMS studies and calculations on alkali metal adduct ions of Ruthenium olefin metathesis catalysts and their catalytic activity in metathesis reactions. Chem. Eur. J. 2009, 15(41), 10948-10959.

16.Cesar A. Marquez, Haoyang Wang, Francesco Fabbretti, Jürgen O. Metzger*. Electron-transfer-catalyzed dimerization of trans-anethole: detection of the distonic tetramethylene radical cation intermediate by extractive electrospray ionization mass spectrometry. J. Am. Chem. Soc. 2008, 130(51), 17208-17209.

17.Haoyang Wang, Jürgen O. Metzger*. ESI-MS Study on first generation Ruthenium olefin metathesis catalysts in solution: direct detection of the catalytically active 14-electron ruthenium intermediate. Organometallics. 2008, 27(12), 2761-2766.

18.Hao-Yang Wang, Qing Hong Tang, Xiang Zhang, Yin-Long Guo*, Long Lu*. Using tandem mass spectrometry to predict chemical transformations of 2-pyrimidinyloxy-N-arylbenzyl amine derivatives in solution. J. Am. Soc. Mass Spectrom. 2006, 17(2), 253-263.

19.Hao-Yang Wang, Xiang Zhang, Yin-Long Guo*, Long Lu*. Mass spectrometric studies of the gas phase retro-Michael type fragmentation reactions of 2-hydroxybenzyl-N-Pyrimidinylamine derivatives. J. Am. Soc. Mass Spectrom. 2005, 16(10), 1561-1573.

20.Hao-Yang Wang, Yin-Long Guo*, Long Lu*. Studies of rearrangement reactions of protonated and lithium cationized 2-pyrimidinyloxy-N-arylbenzylamine derivatives by MALDI-FTICR MS. J. Am. Soc. Mass Spectrom. 2004, 15(12), 1820-1832. ^[2]