複製鏈接
請複製以下鏈接發送給好友

杜大明

鎖定
杜大明,教授,博士生導師,專業:有機化學,應用化學,研究方向:不對稱合成,有機合成化學。研究興趣和領域:1. 新型手性配體、有機催化劑設計合成及不對稱催化反應研究,發展不對稱合成的先進方法學。2. 化學藥物及藥物中間體的合成。
中文名
杜大明
國    籍
中國
民    族
職    業
教師
主要成就
化學藥物及藥物中間體的合成、不對稱合成的先進方法學
職    稱
教授
職    務
博士生導師

杜大明個人履歷

1989年獲鄭州大學理學學士學位
1992年獲南開大學理學碩士學位。
1995年獲南開大學理學博士學位。
1995-1997年山東大學講師。
1997-1999年山東大學副教授。
1996-1997年香港中文大學訪問學者。
1998-1999年香港科技大學博士後。
1999-2001年北京大學博士後。
2001-2008年北京大學化學學院副教授。
2008年起北京理工大學化工與環境學院教授。 [1] 

杜大明主要論著

1. Yang,W.;Du,D. M.* Chiral squaramide-catalyzed highly diastereo- and enantioselective direct Michael addition of nitroalkanes to nitroalkenes. Chem. Commun. 2011,47(47),12706–12708.
2. Yang,W.;Du,D. M.* Chiral squaramide-catalyzed highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes. Adv. Synth. Catal. 2011,353(8),1241–1246.
3. Yang,W.;Du,D. M.* Highly enantioselective Michael addition of nitroalkanes to chalcones using chiral squaramides as hydrogen bonding organocatalysts. Org. Lett. 2010,12(23),5450–5453.
4. Liu,H.;Du,D. M.* Development of diphenylamine-linked bis(imidazoline) ligands and their application in asymmetric Friedel-Crafts alkylation of indole derivatives with nitroalkenes. Adv. Synth. Catal. 2010,352(7),1113–1118.
5. Guo,Q. S.;Du,D. M.*;Xu,J. The development of new double axially chiral phosphoric acids and their catalytic asymmetric transfer hydrogenation of quinolines. Angew. Chem. Int. Ed. 2008,47(4),759–762.
6. Zhou,W. M.;Liu,H.;Du,D. M.* Organocatalytic highly enantioselective Michael addition of 2-hydroxy-1,4-naphthoquinones to nitroalkenes. Org. Lett. 2008,10(13),2817–2820.
7. Liu,H.;Lu,S. F.;Xu,J.;Du,D. M.* Asymmetric Friedel-Crafts alkylation of electron-rich N-heterocycles with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline) and bis(thiazoline)-Zn(II) complexes. Chem. Asian J. 2008,3(7),1111–1121.
8. Liu,H.;Xu,J.;Du,D. M.* Asymmetric Friedel-Crafts alkylation of methoxyfuran with nitroalkenes catalyzed by diphenylamine-tethered bis(oxazoline)-Zn(II) complexes. Org. Lett. 2007,9(23),4725–4728.
9. Lu,S. F.;Du,D. M.*;Xu,J.;Zhang,S. W. Asymmetric conjugate addition of nitroalkanes to nitroalkenes catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) zinc complexes. J. Am. Chem. Soc. 2006,128(23),7418-7419.
10. Du,D. M.*;Fang,T.;Xu,J.;Zhang,S. W. Structurally well-defined,recoverable C3-symmetric tris(b-hydroxy phosphoramide) catalyzed enantioselective borane reduction of ketones. Org. Lett. 2006,8(7),1327-1330.
11. Lu,S. F.;Du,D. M.*;Xu,J. Enantioselective Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by bifunctional tridentate bis(oxazoline)-Zn(II) complex. Org. Lett. 2006,8(10),2115-2118.
12. Du,D. M.*;Lu,S. F.;Fang,T.;Xu,J.* Asymmetric Henry reaction catalyzed by C2-symmetric tridentate bis(oxazoline) and bis(thiazoline) complexes: metal-controlled reversal of enantioselectivity. J. Org. Chem. 2005,70(9),3712-3715.
13. Fang,T.;Du,D. M.*;Lu,S. F.;Xu,J.* Synthesis of C3-symmetric tris(b-hydroxy amide) ligands and their Ti(IV) complex-catalyzed enantioselective alkynylation of aldehydes. Org. Lett. 2005,7(11),2081-2084.
14. Du,D. M.;Carlier,P. R.* Development of bivalent acetylcholinesterase inhibitors as potential therapeutic drugs for Alzheimer’s disease. Current Pharm. Design 2004,10(25),3141-3156.
15. Carlier,P. R.*;Du,D. M.;Han,Y. F.;Liu,J.;Perola,E.;Williams,I. D.;Pang,Y. P. Dimerization of an inactive fragment of Huperzine A produces a drug with twice the potency of the natural product. Angew. Chem. Int. Ed. 2000,39(10),1775-1777.
16. Yang,X. P.;Du,D. M.;Li,Q.;Mak,T. C. W.;Wong,H. N. C.* Synthesis,structure and inclusion properties of 1,4,15,18-tetrahedro-1,4,15,18-tetraoxodibenzo[b,h]tetraphenylene. Chem. Commun. 1999,(16),1607-1608.
參考資料