朱麗君

研究方向

● 藥物吸收與代謝途徑及機理研究

發表論文

[1] Zhu LJ, Liu XW, Zhu L, Zhang XF, Fu XJ, Huang JJ, Yuan M*, Identification of human cytochrome P450 isozymes involved in the metabolism of naftopidil enantiomers in vitro. Journal of Pharmacy and Pharmacology. doi:10.1111/jphp.12281, 2014.

[2] Zhu LJ, Lu LL, Guo ES, Wu JJ, Wang Y, Hu M, Liu ZQ*, The influence of aconitine, an active and toxic alkaloid from Aconitum, on the pharmacokinetic of CYP3A probe drug buspirone in rats. Drug Metabolism Letters. doi: 10.2174/1872312808666140505162139, 2014.

[3]ZhuLJ, Yang XS, Zhou J, Tang L, Xia BJ, Hu M, Liu ZQ*, The exposure of highly toxic aconitine does not significantly impact the activity and expression of cytochrome P450 3A in rats determined by a novel ultra performance liquid chromatography-tandem mass spectrometric method of a specific probe buspirone, Food and Chemical Toxicololy, 51(1):396-403, 2013.

[4]Zhang YY, Liu XW, Zhu LJ, Yuan M*, Simultaneous stereoselective analysis of naftopidil and O-desmethyl naftopidil enantiomers in rat feces using an online column-switching high performance liquid chromatography method, Biomedical Chromatography. DOI:10.1002/bmc. 3112, 2013.

[5]Cai Z,Wang Y, Zhu LJ, Liu ZQ*, Nanocarriers: A General Strategy for Enhancement of Oral Bioavailability of Poorly Absorbed or Pre-Systemically Metabolized Drugs, Current Drug Metablism, 11(2): 197-207, 2010.

[6 ]楊曉珊, 吳錦俊, 盧琳琳, 朱麗君*. 劉中秋. 附子藥代動力學研究進展，世界中醫藥，9(2): 171-174, 2014.

[7]朱麗君, 潘仕榮*, 兩性黴素 B/聚乙二醇-聚天冬氨酸苄酯嵌段共聚物納米膠束的製備與性能,中國藥學雜誌, 45(05):359-365, 2010.

[8]張廣平, 朱麗君, 周娟, 唐斕, 劉中秋, 葉祖光*, 附子配伍甘草對 CYP3A4 體內活性的影響研究,中國中藥雜誌, 37(15):2206-2209, 2012. ^[1]