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史慶華

(中國科學技術大學生命科學學院教授)

鎖定
史慶華,男,1964年出生於江蘇徐州,博士,中國科學技術大學教授、博士生導師,國家傑出青年基金獲得者、科技部重大科學研究計劃專家組專家。
中文名
史慶華
出生地
江蘇徐州
出生日期
1964年出
畢業院校
南京師範大學
學位/學歷
博士
專業方向
分子細胞遺傳學/腫瘤染色體異常的發生途徑
職    務
博士生導師 [1] 
主要成就
國家傑出青年基金獲得者 [1] 
任職院校
中國科學技術大學
職    稱
中國科學技術大學教授

史慶華人物經歷

史慶華 史慶華
1998年畢業於南京師範大學,獲博士學位。
1992年10月-1993年11月德國國立環境與健康研究中心訪問學者。
1996年10月-1997年12月作為聯合培養博士生在德國國立環境與健康研究中心(GSF-National Research Center for Environment and Health, Germany)學習。
1998年11月-2001年12月加拿大卡加里大學(University of Calgary, Canada)博士後。
2002年1月-2004年12月哈佛大學醫學院(Harvard Medical School, USA)Research Fellow。
2004年入選中國科學院“引進國外傑出人才”項目,同年12月全職全時回國,現為中國科技大學合肥微尺度物質科學國家實驗室PI(Principal Investigator)和生命科學學院教授、博士生導師。
2005年7月通過中科院”百人計劃”擇優支持。

史慶華科研成果

工作以來共發表研究論文30餘篇,已作為第一或聯繫作者在Nature、Am J Hum Genet(影響因子12.34) 等SCI雜誌上發表論文11篇,被他引200餘次;在2005年,論文被引用80餘次。
擔任《PloS One》、《遺傳》、《中國細胞生物學報》和《生命科學》等多家雜誌的常務編委或編委。作為第一或通訊作者在NatureAmerican Journal of Human Genetics、Human Genetics、Cell Cycle、Bioinformatics和Cell Research等雜誌上發表SCI論文30餘篇,被他人引用1000餘次。

史慶華科研項目

中國科學院“百人計劃”啓動經費課題、國家自然科學基金項目

史慶華研究方向

1、分子細胞遺傳學/腫瘤染色體異常的發生途徑
2、生殖生物學/配子發生的遺傳調控 [1] 

史慶華論文專著

(1) Chromosome nondisjunction yields tetraploid rather than aneuploid cells in human cell lines. - NATURE - 200510 - 437:1038-1042
(2) Absence of age effect on meiotic recombination between human X and Y chromosomes - AMERICAN JOURNAL OF HUMAN GENETICS - 2002 - 71(2):254-261
(3) Lagging chromosomes entrapped in micronuclei are not‘lost’by cells - Cell Research - 201202 - 2012
(4) Recurrent trisomy and Robertsonian translocation of chromosome 14 in murine iPS cell lines - Chromosome Research - 201110 - 19(7):857-68
(5) Complex relationship between meiotic recombination frequency and autosomal synaptonemal complex length per cell in normal human males - American Journal of Medical Genetics - 201202 - Epub ahead of print
(6) Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries - PLoS One - 201101 - 6(1):e16046
(7) Prediction of novel pre-microRNAs with high accuracy through boosting and SVM - Bioinformatics - 201103 - 27(10):1436-1437
(8) The fate of micronucleated cells post X-irradiation detected by live cell imaging - DNA Repair (Amst) - 201103 - 10:629-638
(9) Multiple origins of spontaneously arising micronuclei in HeLa cells: Direct evidence from long-term live cell imaging - MUTATION RESEARCH - 200811 - 646(1-2):41-49
(10) Abnormal synapsis and recombination in an azoospermic male carrier of a reciprocal translocation t(1;21). - FERTILITY AND STERILITY - 200902 - 91(4):1293 e17-22
(11) Cryopreservation has no effect on meiotic recombination and synapsis in testicular tissues - FERTILITY AND STERILITY - 200808 - 91(4):1404-7
(12) Cigarette smoking and aneuploidy in human sperm - MOLECULAR REPRODUCTION AND DEVELOPMENT - 200108 - 59(4):417-421
(13) Recombination in the pseudoautosomal region in a 47, XYY male - HUMAN GENETICS - 200108 - 109(2):143-145
(14) Increased nondisjunction of chromosome 21 with age in human peripheral lymphocytes - MUTATION RESEARCH - 200007 - 452(1):27-36
(15) Incidence of mosaic cell lines in vivo and malsegregation of chromosome 21 in lymphocytes in vitro of trisomy 21 patients: detection by fluorescence in situ hybridization on binucleated lymphocytes - HUMAN GENETICS - 200001 - 106(1):29-35
(16) Aneuploidy in human spermatozoa: FISH analysis in men with constitutional chromosomal abnormalities, and in infertile men - REPRODUCTION - 200105 - 121(5):655-666
(17) Single sperm typing demonstrates that reduced recombination is associated with the production of aneuploid 24,XY human sperm - AMERICAN JOURNAL OF MEDICAL GENETICS - 200102 - 99(1):34-38
(18) Multicolor fluorescence in situ hybridization analysis of meiotic chromosome segregation in a 47,XYY male and a review of the literature - AMERICAN JOURNAL OF MEDICAL GENETICS - 200007 - 936(1):40-46
(19) Spontaneous frequencies of aneuploid and diploid sperm in 10 normal Chinese men: assessed by multicolor fluorescence in situ hybridization - CYTOGENETICS AND CELL GENETICS - 2000 - 90(1-2):79-83
(20) Aneuploidy in human sperm: a review of the frequency and distribution of aneuploidy, effects of donor age and lifestyle factors - CYTOGENETICS AND CELL GENETICS - 2000 - 90(3-4):219-226
(21) The polycomb group protein Bmi-1 represses the tumor suppressor PTEN and induces epithelial-mesenchymal transition in human nasopharyngeal epithelial cells - J Clin Invest - 200912 - 119(12):3626-36
(22) Comparative proteome profile of immature rat ovary during primordial follicle assembly and development - Proteomics - 200907 - 9(13):3425-34
(23) Nucleophosmin/B23 inhibits Eg5-mediated microtubule depolymerization by inactivating its ATPase activity - J Biol Chem - 201006 - 285(25):19060-7 [1] 
參考資料