劉奇蹟

1987.9-1991.7華中科技大學同濟醫學院學士

1998.9-2001.7山東大學醫學院 碩士

2002.9-2005.6山東大學醫學院 博士

2007.9-至今 山東大學教授

2008.9-2009.8 香港大學李嘉誠醫學院鄭裕彤獎助金學者

2004.9-2007.8 山東大學副教授

2004.2-2005.2 美國肯塔基大學醫學院訪問學者

2001.7-2004.8 山東大學講師

1991.7-1998.8 山東醫科大學助教講師

2023.9-2023.12 濱州醫學院副院長（試用期一年）。 ^{[7]  [9]} 

2023.12-康復大學（籌）臨時黨委委員、領導小組成員。 ^[10-12] 

2023年9月21日，山東省人民政府決定，任命：劉奇蹟為濱州醫學院副院長（試用期一年）。 ^[7] 

2023年12月14日，山東省人民政府決定，免去：劉奇蹟的濱州醫學院副院長職務。 ^[9] 

1.常見自身免疫性疾病易感基因的鑑定及其發生的遺傳學機制

2.罕見孟德爾遺傳病致病基因的鑑定分離及功能分析

1. ETS-1基因在系統性紅斑狼瘡發生中的機制研究

國家自然科學基金2011.1-2013.12

2. 一新的常染色體顯性遺傳性痙 ^[1]  攣性截癱大家系致病基因的定位候選克隆

國家自然科學基金2008.1—2010.12

3. 遺傳性痙攣性截癱發生的分子機理研究 ^[2] 

山東省中青年科學家獎勵基金2008.1-2010.12

4. 漢族人羣哮喘易感基因的候選基因關聯分析

山東省衞生系統傑出人才計劃2009.1-2011.12

5. TIM基因家族在哮喘發生中的作用機制研究

國家自然科學基金2007.1-2009.12

6. 中國漢族人羣哮喘易感基因的相關研究

國家自然科學基金2004.1-2006.12

1.Shan S, Dang J, Li J, Yang Z, Zhao H, Xin Q, Ma X, Liu Y, Bian X, Gong Y,Liu Q.ETS1 variants confer susceptibility to ankylosing spondylitis in Han Chinese.Arthritis Res Ther.2014 Apr 4;16(2):R87.

2. Ma X, Liu Y, Zhang H, Qiu R, Zhao H, Xin Q, Shan S, Dang J, Li J, Yang Z, Gong Y,Liu Q.Evidence for genetic association of CARD9 and SNAPC4 with ankylosing spondylitis in a Chinese Han population.J Rheumatol. 2014 Feb;41(2):318-24.

3. Dang J, Shan S, Li J, Zhao H, Xin Q, Liu Y, Bian X,Liu Q.Gene-gene Interactions of IRF5, STAT4, IKZF1 andETS1in systemic lupus erythematosus.Tissue Antigens. 2014 Jun;83(6):401-8

4. Qiu R, Zhang H, Zhao H, Li J, Guo C, Gong Y,Liu Q.Genetic variants on 17q21 are associated with ankylosing spondylitis susceptibility and severity in a Chinese Han population.Scand J Rheumatol.2013;42(6):469-72.

5. Liu Y, Zhang H, Li J, Zhao H, Xin Q, Shan S, Dang J, Bian X,Liu Q.Association of common variants in KIF21B and ankylosing spondylitis in a Chinese Han population: a replication study.Immunogenetics.2013 Dec;65(12):835-9.

6. Zhao H, Yang W, Qiu R, Li J, Xin Q, Wang X, Feng Y, Shan S, Liu Y, Gong Y,Liu Q.An intronic variant associated with systemic lupus erythematosus changes the binding affinity of Yinyang1 to downregulate WDFY4.Genes Immun.2012 Oct;13(7):536-42.

7. Fang Q, Zhao H, Wang A, Gong Y,Liu Q.Association of genetic variants in chromosome 17q21 and adult-onset asthma in a Chinese Han population.BMC Med Genet.2011 Oct 11;12:133.

8. Guo C, Xia Y, Yang Q, Qiu R, Zhao H,Liu Q.Association of the ANTXR2 gene polymorphism and ankylosing spondylitis in Chinese Han.Scand J Rheumatol.2012 Feb;41(1):29-32.

9. Zhao B, Abdelmoudjib G, Li J, Li H, Wei C, Gong Y,Liu Q.Two polymorphisms in the TIM-4 gene are associated with asthma in a Chinese han population.Int J Immunogenet.2010 Aug 19. [Epub ahead of print]

10. Yang W, Shen N, Ye DQ,Liu Q,et al.Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus.PLoS Genet.2010 Feb 12;6(2):e1000841

11. Saadi A, Gao G, Li H, Wei C, Gong Y,Liu Q. Association study between vitamin D receptor gene polymorphisms and asthma in the Chinese Han population: a case-control study.BMC Med Genet.2009 Jul 21;10:71

12.Liu Q,Xia Y, Zhang W, Li J, Wang P, Li H, Wei C, Gong Y.A functional polymorphism in the SPINK5 gene is associated with asthma in a Chinese Han Population.BMC Med Genet.2009 Jun 17;10:59.

13. Li J,Liu Q, Wang P, Li H, Wei C, Guo C, Gong Y.Lack of associationbetween three promoter polymorphisms of PTGDR gene and asthma in a Chinese Han population.Int J Immunogenet.2007 Oct;34(5):353-7.

14. Liu QJ, Lin SS, Wang P, et al.A functional polymorphism of Tim-1 promoter region is associated with asthma in a Chinese population.International Archives of Allergy and Immunology, 2007,144:197-202.

15. Wang P,Liu QJ, Li JS, et al.Lack of association between ADAM33 gene and asthma in Chinese population.International Journal of Immunogenetics,2006,8:303-306.

16. Li JS,Liu QJ, Wang P, et al.Absence of association between two insertion/deletion coding genetic polymorphisms of TIM-1 gene and asthma in Chinese Han population.International Journal of Immunogenetics,2006,12:417-421.

1. Wang X, Xin Q, Li L, Li J, Zhang C, Qiu R, Qian C, Zhao H, Liu Y, Shan S, Dang J, Bian X, Shao C, Gong Y,Liu Q.Exome sequencing reveals a heterozygous DLX5 mutation in a Chinese family with autosomal-dominant split-hand/foot malformation.Eur J Hum Genet. 2014 Feb 5. doi: 10.1038/ejhg.2014.7.

2. Feng Y,Ke X,Zhai M,Xin Q,Gong Y,Liu Q.Novel deletion of SPAST in a Chinese family with hereditary spastic paraplegia.Singapore Med J. 2013 May;54(5):251-4

3. Qiu R, Yang Y, Zhao H, Li J, Xin Q, Shan S, Liu Y, Dang J, Yu X, Gong Y,Liu Q.Signal transducer and activator of transcription 6 directly regulates human ORMDL3 expression.FEBS J.2013 May;280(9):2014-26.

4. Xin Q, Li L, Li J, Qiu R, Guo C, Gong Y,Liu Q.Eight-alanine duplication in homeobox D13 in a Chinese family with synpolydactyly.Gene.2012 May 10;499(1):48-51.

5. Wang X, Li L, Li J, Sun J, Heng X, Gong Y,Liu Q.Pathogenic gene screening and mutation detection in a Chinese family with multiple osteochondroma.Genet Test Mol Biomarkers.2012 Jul;16(7):827-32.

6. Lin P, Mao F,Liu Q,Yang W, Shao C, Yan C, Gong Y.A novel deletion mutation in GJB1 causes X-linked Charcot-Marie-Tooth disease in a Han Chinese family.Muscle Nerve.2010 Dec;42(6):922-6.

7. Lin P, Mao F,Liu Q,Shao C, Yan C, Gong Y.Prenatal diagnosis of autosomal dominant hereditary spastic paraplegia (SPG42) caused by SLC33A1 mutation in a Chinese kindred. Prenat Diagn. 2010 May;30(5):485-6.

8. Zou Y, Mi J, Cui J, Lu D, Zhang X, Guo C, Gao G,Liu Q,Chen B, Shao C, Gong Y. Characterization of nuclear localization signal in the N terminus of CUL4B and its essential role in cyclin E degradation and cell cycle progression.J Biol Chem.2009 Nov 27;284(48):33320-32

9. Lin P, Li J,Liu Q, Mao F, Li J, Qiu R, Hu H, Song Y, Yang Y, Gao G, Yan C, Yang W, Shao C, Gong Y.A missense mutation in SLC33A1, which encodes the acetyl-CoA transporter, causes autosomal-dominant spastic paraplegia (SPG42) .Am J Hum Genet.2008 Dec;83(6):752-9.

10. Xia Y, Jiang B, Zou Y, Gao G, Shang L, Chen B,Liu Q,Gong Y.Sp1 and CREB regulate basal transcription of the human SNF2L gene.Biochem Biophys Res Commun.2008 Apr 4;368(2):438-44.

11. Zou Y, Liu Q,Chen B, Zhang X, Guo C, Zhou H, Li J, Gao G, Guo Y, Yan C, Wei J, Shao C, Gong Y. Mutation in CUL4B, a member of cullin-RING ubiquitin ligase complex, causes X-linked mental retardation.American Journal of Human Genetics,2007, 80: 561-566.

12. Zhu G, Ke X,Liu Q, Li J, Chen B, Shao C, Gong Y.Recurrence of the D100N mutation in a Chinese family with brachydactyly type A1: evidence for a Mutational hot spot in the Indian hedgehog gene.Am J Med Genet A. 2007 Jun1;143(11):1246-8.

13. Zhang X,Liu Q,Chen B, et al. A locus for nonspecific X-linked mental retardation mapped to a 22.3 cM region of Xp11.3-q22.3.Am J Med Genet A. 2004,129(3):286-9

14. Liu Q,Gong Yaoqin, Zhang XY, et al. Candidate gene analysis ofSmith-Fineman-Myers Syndrome.Journal of Shandong University (health Sciences), 2004,42(1):29-31

15. Liu Q, Gong YQ, Zhang XY, et al. Characterization of genomic structure and mutation analysis of SMARCA1 gene in a Smith-Fineman-Myers syndrome family.Yi Chuan Xue Bao, 2004,31(2):114-8 ^[3]