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黃方

(中國石油大學教授)

鎖定
黃方,男,漢族,1973年11月出生,無黨派人士,研究生學歷,中國石油大學(華東)教授、博士生導師。泰山學者海外特聘專家。
中文名
黃方
國    籍
中國
民    族
漢族
畢業院校
山東大學
瑞士巴塞爾大學
性    別
學習與工作經歷
1991.9-1995.7
山東大學,化學院,學士學位
1997.9-2000.7
山東大學,化學院,碩士學位
2000.8-2004.6
瑞士巴塞爾大學,物理化學研究所,博士(Prof. Werner Nau)
2004.7-2008.6
英國劍橋大學MRC蛋白質工程中心,博士後(Sir Alan Fersht)
2008.6-2009.9
英國劍橋大學MRC蛋白質工程中心,科學家(Investigator Scientist),長期職位(Established)
2009.6-
中國石油大學生物工程與技術中心,教授,博士生導師
獲獎情況
2012年,山東青年五四獎章 [1] 
榮譽稱號
泰山學者海外特聘專家 [2] 
論文
1.Zhao Y, et al.(2016) Stable folding intermediates prevent fast interconversion between the closed and open states of Mad2 through its denatured state.Protein engineering, design & selection : PEDS29(1):23-29.
2.Yue T, Xu Y, Sun M, Zhang X, & Huang F (2016) How tubular aggregates interact with biomembranes: wrapping, fusion and pearling.Phys. Chem. Chem. Phys.18(2):1082-1091.
3.Yue T, Xu Y, Li S, Zhang X, & Huang F (2016) Lipid extraction mediates aggregation of carbon nanospheres in pulmonary surfactant monolayers.Phys. Chem. Chem. Phys.18(28):18923-18933.
4.Yue T, Tian F, Sun M, Zhang X, & Huang F (2016) Inter-tube adhesion mediates a new pearling mechanism.Phys. Chem. Chem. Phys.18(1):361-374.
5.Yue T, et al.(2016) How transmembrane peptides insert and orientate in biomembranes: a combined experimental and simulation study.Phys. Chem. Chem. Phys.18(26):17483-17494.
6.Yue T, Li S, Xu Y, Zhang X, & Huang F (2016) Interplay Between Nanoparticle Wrapping and Clustering of Inner Anchored Membrane Proteins.J. Phys. Chem. B.
7.Wang XJ, et al.(2016) Steering graphene quantum dots in living cells: lighting up the nucleolus.J Mater Chem B4(4):779-784.
8.Wang X, et al.(2016) Active tumor-targeting luminescent gold clusters with efficient urinary excretion.Chem Commun (Camb)52(59):9232-9235.
9.He H, et al.(2016) An Ultra-High Fluorescence Enhancement and High Throughput Assay for Revealing Expression and Internalization of Chemokine Receptor CXCR4.Chemistry22(17):5863-5867.
10.Chi H, Wang X, Li J, Ren H, & Huang F (2016) Chaperonin-enhanced Escherichia coli cell-free expression of functional CXCR4.J. Biotechnol.231:193-200.
11.Yue TT, Wang XJ, Zhang XR, & Huang F (2015) Molecular modeling of interaction between lipid monolayer and graphene nanosheets: implications for pulmonary nanotoxicity and pulmonary drug delivery.Rsc Adv5(38):30092-30106.
12.Yue T, Zhang X, & Huang F (2015) Molecular modeling of membrane responses to the adsorption of rotating nanoparticles: promoted cell uptake and mechanical membrane rupture.Soft matter11(3):456-465.
13.Yu D, et al.(2015) Enhanced photocurrent production by bio-dyes of photosynthetic macromolecules on designed TiO2 film.Scientific reports5:9375.
14.Wang X, et al.(2015) A two-component active targeting theranostic agent based on graphene quantum dots.J. Mater. Chem. B3:3583--3590.
15.Wang X, Huang H, Sun C, & Huang F (2015) Structural analysis of bacteriorhodopsin solubilized by lipid-like phosphocholine biosurfactants with varying micelle concentrations.J. Colloid Interface Sci.437:170-180.
16.Ge BS, Wang MQ, Li JQ, Liu JG, & Huang F (2015) Maltose binding protein facilitates functional production of engineered human chemokine receptor 3 in Escherichia coli.Process Biochem.50(2):285-293.
17.Chi H, Wang X, Li J, Ren H, & Huang F (2015) Folding of newly translated membrane protein CCR5 is assisted by the chaperonin GroEL-GroES.Scientific reports5:17037.
18.Yue T, Zhang X, & Huang F (2014) Membrane monolayer protrusion mediates a new nanoparticle wrapping pathway.Soft matter10(12):2024-2034.
19.Yue T, Zhang X, & Huang F (2014) Molecular modeling of membrane tube pearling and the effect of nanoparticle adsorption.Phys. Chem. Chem. Phys.16(22):10799-10809.
20.Yue T, Zhang X, & Huang F (2014) Membrane monolayer protrusion mediates a new nanoparticle wrapping pathway.Soft matter10(12):2024-2034.
21.Yu D, et al.(2014) Triton X-100 as an effective surfactant for the isolation and purification of photosystem I from Arthrospira platensis.Photosynth. Res.120(3):311-321.
22.Yu D, et al.(2014) Effect of surfactants on apparent oxygen consumption of photosystem I isolated from Arthrospira platensis.Photosynth. Res.122(2):203-213.
23.Wang X, et al.(2014) Multifunctional graphene quantum dots for simultaneous targeted cellular imaging and drug delivery.Colloids and surfaces. B, Biointerfaces122:638-644.
24.Wang M, Ge B, Yang Q, Jiang X, & Huang F (2014) High-level production of biologically active chemokines in Escherichia coli.Process Biochem.49(4):706-714.
25.Song B, et al.(2014) Irreversible Denaturation of Proteins through Aluminum-Induced Formation of Backbone Ring Structures.Angew. Chem. Int. Ed.53(25):6358-6363.
26.Qu JB, et al.(2014) Coating gigaporous polystyrene microspheres with cross-linked poly(vinyl alcohol) hydrogel as a rapid protein chromatography matrix.ACS applied materials & interfaces6(15):12752-12760.
27.Yue T, Wang X, Huang F, & Zhang X (2013) An unusual pathway for the membrane wrapping of rodlike nanoparticles and the orientation- and membrane wrapping-dependent nanoparticle interaction.Nanoscale5(20):9888-9896.
28.Yu D, Zhu G, Liu S, Ge B, & Huang F (2013) Photocurrent activity of light-harvesting complex II isolated from spinach and its pigments in dye-sensitized TiO2 solar cell.Int. J. Hydrogen Energy38(36):16740-16748.
29.Wang X, et al.(2013) Solubilization and Stabilization of Isolated Photosystem I Complex with Lipopeptide Detergents.PLoS One8(9):e76256.
30.Wang M, et al.(2013) Milligram Production and Biological Activity Characterization of the Human Chemokine Receptor CCR3.PLoS One8(6):e65500.
31.Qu JB, Shao HH, Jing GL, & Huang F (2013) PEG-chitosan-coated iron oxide nanoparticles with high saturated magnetization as carriers of 10-hydroxycamptothecin: preparation, characterization and cytotoxicity studies.Colloids and surfaces. B, Biointerfaces102:37-44.
32.Huang F, Johnson CM, Petrovich M, & Fersht AR (2013) Don't waste good methods on bad buffers and ambiguous data.Proc Natl Acad Sci U S A110(5):E331-332.
33.Ge B, et al.(2013) Combinational biosynthesis of phycocyanobilin using genetically-engineered Escherichia coli.Biotechnol. Lett35(5):689-693.
34.Yu D, Huang F, & Xu H (2012) Determination of critical concentrations by synchronous fluorescence spectrometry.Analytical Methods4(1):47-49.
35.Leith JS, et al.(2012) Sequence-dependent sliding kinetics of p53.Proc Natl Acad Sci U S A109(41):16552-16557.
36.Tafvizi A, Huang F, Fersht AR, Mirny LA, & van Oijen AM (2011) A single-molecule characterization of p53 search on DNA.Proc Natl Acad Sci U S A108(2):563-568.
37.Rajagopalan S, Huang F, & Fersht AR (2011) Single-Molecule characterization of oligomerization kinetics and equilibria of the tumor suppressor p53.Nucleic Acids Res.39(6):2294-2303.
38.Huang F, Ying L, Neuweiler H, & Fersht AR (2009) Reply to Campos et al.: Direct observation versus ambiguous kinetics and thermodynamics.Proce Natl Acad Sci USA106(52):DOI: 10.1073/pnas.0913321107.
39.Huang F, Ying L, & Fersht AR (2009) Direct observation of barrier-limited folding of BBL by single-molecule fluorescence resonance energy transfer.Proc Natl Acad Sci USA106(38):16239-16244.
40.Huang F, et al.(2009) Multiple conformations of full-length p53 detected with single-molecule fluorescence resonance energy transfer.Proc Natl Acad Sci USA106:20758-20763.
41.Huang F, et al.(2009) Time-resolved fluorescence resonance energy transfer study shows a compact denatured state of the B domain of protein A.Biochemistry48(15):3468-3476.
42.Tafvizi A, et al.(2008) Tumor suppressor p53 slides on DNA with low friction and high stability.Biophys. J.95(1):L01-L03.
43.Huang F, Settanni G, & Fersht AR (2008) Fluorescence resonance energy transfer analysis of the folding pathway of Engrailed Homeodomain.Protein engineering, design & selection : PEDS21(3):131-146.
44.Huang F, Sato S, Sharpe TD, Ying L, & Fersht AR (2007) Distinguishing between cooperative and unimodal downhill protein folding.Proc Natl Acad Sci USA104(1):123-127.
45.Huang F & Nau WM (2005) Photochemical techniques for studying the flexibility of polypeptides.Res. Chem. Intermed.31(7-8):717-726.
46.Pischel U, Huang F, & Nau WM (2004) Intramolecular singlet-singlet energy transfer in antenna-substituted azoalkanes.Photochem Photobiol Sci3(3):305-310.
47.Marquez C, Huang F, & Nau WM (2004) Cucurbiturils: molecular nanocapsules for time-resolved fluorescence-based assays.IEEE Trans Nanobioscience3(1):39-45.
48.Huang F, Hudgins RR, & Nau WM (2004) Primary and secondary structure dependence of peptide flexibility assessed by fluorescence-based measurement of end-to-end collision rates.J. Am. Chem. Soc.126(50):16665-16675.
49.Nau WM, et al.(2003) Exploiting long-lived molecular fluorescence.Chimia57(4):161-167.
50.Huang F & Nau WM (2003) A conformational flexibility scale for amino acids in peptides.Angew. Chem. Int. Ed.42(20):2269-2272.
51.Gao X, et al.(2003) Progresses of derivatization techniques for analyses of carbohydrates.Anal. Lett.36(7):1281-1310.
52.Yang J, Huang F, Wang M, Wu X, & Sun C (2002) Study on the molecular recognitions of calix[n]arenes to 2,3-diaminonaphthalene by using fluorometric technique.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy58(8):1775-1778.
53.Liu R, et al.(2002) Resonance Rayleigh light-scattering of thiamine hydrochloride-nucleic acids-cetyl trimethyl ammonium bromide systems and their analytical application.J. Trace Microprobe Tech.20(3):363-376.
54.Hudgins RR, Huang F, Gramlich G, & Nau WM (2002) A fluorescence-based method for direct measurement of submicrosecond intramolecular contact formation in biopolymers: an exploratory study with polypeptides.J. Am. Chem. Soc.124(4):556-564.
55.Huang F, et al.(2001) The study of spectrosgraphic properties and molecular recognition of cali.Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy57A(5):1025-1030.
56.Yang J, Cao X, Huang F, Wu X, & Zhou G (2000) Fluorimetric determination of carbohydrates with 2,3-diaminonaphthalene.Chem. J. Internet2(1).
57.Wu X, et al.(2000) A study on the fluorescence system of Sc-BPMPHD-CTMAB and its analytical application.Chem. Res. Chin. Uni.16(1):93-95.
58.Wang M, Yang J, Wu X, & Huang F (2000) Study of the interaction of nucleic acids with acridine red and CTMAB by a resonance light scattering technique and determination of nucleic acids at nanogram levels.Anal. Chim. Acta422(2):151-158.
59.Ma Q, Yang J, Wu X, Huang F, & Sun L (2000) A selective fluorimetric method for the determination of some b-lactamic antibiotics.Anal. Lett.33(13):2689-2699.
60.Huang F, Liu X, Zhou G, Wu X, & Yang J (2000) The progress of the derivatization methods of carbohydrate.Chem. Online2000(1-12):c00023.
61.Wu X, et al.(1999) Study of the reaction between nucleic acids and Tb-BPMPHD-CTMAB complex and its analytical application.Anal. Lett.32(12):2417-2425.
62.Wu X, Tong C, Su B, Huang F, & Yang J (1999) Determination of dopamine by fluorimetry.Chin. J. Anal. Chem.27(9):1069-1071.
63.Wu X, Tong C, Su B, Huang F, & Yang J (1999) Terbium(III) as fluorescence probe for the determination of epinephrine.Shandong Daxue Xuebao, Ziran Kexueban34(3):352-355.
64.Yang J, et al.(1998) Fluorometric determination of epinephrine with o-phenylenediamine.Anal. Chim. Acta363(1):105-110.
65.Yang J, Ma Q, Huang F, Sun L, & Dong J (1998) A new fluorimetric method for the determination of ascorbic acid.Anal. Lett.31(15):2757-2766.
參考資料