鹽酸伊立替康三水合物

中文名稱：鹽酸伊立替康三水合物

中文別名：鹽酸依立替康三水合物;L-(+)-N-[4-[[(2,4-二氨基-6-蝶啶基)甲氨基]苯甲三水合物;三水鹽酸伊立替康;鹽酸三水伊立替康三水合物;伊立替康鹽酸鹽三水合物

英文名稱：Irinotecan hydrochloride trihydrate

英文別名：(+)-7-Ethyl-10-hydroxycamptothecine 10-(1,4'-bipiperidine)-1'-carboxylate, monohydrochloride, trihydrate; Camptosar; Irinotecan HCl trihydrate; (1,4'-Bipiperidine)-1'-carboxylic acid, 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, monohydrochloride, trihydrate, (S)-; (1,4'-bipiperidine)-1'-carboxylicacid,4,11-diethyl-3,4,12,14-tetrahydro-4-hyd monohydrochloride, trihydrate; roxy-3,14-dioxo-1h-pyrano(3',4',6,7)indolizino(1,2-b)quinolin-9-ylester,mono; trihydrate,(s)-hydrochlorid trihydrate; irinotecan monohydrochloride trihydrate; [1,4'-bipiperidine]-1'-carboxylic acid (s)-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano; [3',4',6,7]indolizino[1,2-b]quinolin-9-yl ester, hcl trihydrate; (s)-[1,4'-bipiperidine]-1'-carboxylic acid 4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1h-pyrano; [3',4':6,7]indolizino[1,2-b]quinolin-9-yl ester hydrochloride trihydrate; irinotecanhydrochloridetrihydrate(cpt-11)

分子量：623.139

熔點：250-256℃ (dec.)

：主要用於治療消化系統腫瘤如胃癌、結腸癌、直腸癌、肺癌等,也用於治療白血病、葡萄胎和絨毛膜上皮癌。伊立替康是一種經過化學結構修飾的天然喜樹鹼的衍生物。它是療效確切、毒副作用較小的新型抗癌藥物,主要用於治療肺癌、結直腸癌、胃癌、子宮癌、卵巢癌等癌症。