阮剛

先後在哈爾濱工程大學和天津大學(導師：王亞權教授)獲化學工程學士和碩士學位。從博士研究(the National University of Singapore, 導師：馮思慎教授)起進入生物納米科技領域。先後在Emory University & Georgia Institute of Technology和 the Ohio State University(導師：Prof. Jessica Winter)從事博士後研究。最近在the Ohio State University擔任研究科學家和項目負責人(Research Scientist and Principal Investigator)職務。於2012年入選中組部國家 ，2013年3月正式加入南京大學新成立的現代工學院生物醫學工程系任教授。 ^[1] 

納米生物材料、分子影像、藥物釋放、生物傳輸。 ^[1] 

生物醫學工程導論(Introduction to Biomedical Engineering)、組織工程與再生醫學(Tissue Engineering and Regenerative Medicine, 與胡勇教授合作開設)、國際聯合工程設計與研究暑期實踐(NJU-OSU Joint International Engineering Design & Research Summer Experience, 與美國the Ohio State University工學院Mark Ruegsegger教授合作開設)。 ^[1] 

阮剛教授團隊通過在以下方向的研究，致力於推動生物納米技術領域的發展。 1.新一代納米生物材料的開發 2.納米結構與生物系統相互作用的基礎研究 3.納米技術的生物醫學應用。阮剛教授在生物納米科技領域已作出多項有重大影響的工作,如：(1)連續變色的熒光納米顆粒,(2)納米傳送帶技術, (3) 納米複合顆粒在生物檢測、生物成像、生物調控等方面的應用, (4) 量子點在活細胞內部的運動規律研究。共發表論文約30篇，其中多篇論文發表在國際高層次期刊上(如Journal of the American Chemical Society, Nano Letters, Biomaterials, Journal of Controlled Release)。論文總被引用(絕大多數屬他引)次數近1000次(單篇最高引用次數約350次)。工作成果被多家國際媒體如 Science Daily, Scientific American, Nanotechnology Now, Popular Science, R&D Magazine報道 (包括Nanowerk 和Imaging & Microscopy上作為亮點報道)。所發表論文曾被三家國際主要科技刊物或數據庫評為”Hottest Paper”或類似稱號。在高水平國際會議和高等院校作受邀學術報告近十次，多次撰寫受邀綜述論文和教材,為多種國際期刊(如Chemical Society Reviews，Nature Communications, ACS Nano)審稿, 曾擔任高水平國際會議Society for Biomaterials Annual Meeting的分會共同主持人和American Institute of Chemical Engineers Annual Meeting獎勵的評委。獲National Science Foundation (USA), State of Ohio, Institute for Materials Research (the Ohio State University)的多項基金資助(作為子課題負責人co-PI)。在技術產業化方面,有多項美國專利申請; 共同創立高科技起步公司Core Quantum Technologies Inc.; 獲Fisher Business Plan Competition 冠軍; 獲Ohio州的 3rd Frontier program，US National Science Foundation的Innovation Corps program和Small Business Innovation Research program獎勵資助和私人風險投資進行產業化開發。美國Baltimore市著名社會公益創業孵化器顧問。 ^[1] 

1、Ruan, G. * & Winter, J.O. * Chemical Engineering at the Intersection of Nanotechnology and Biology. Chemical Engineering Progress (CEP), Dec 2012 special issue. (Invited)

2、Ruan, G. & Winter, J.O.* Alternating-color quantum dot nanocomposites for particle tracking. Nano Letters 11, 941-945 (2011)

3、Ruan, G., Vieira, G. (equal contribution with Ruan, G.), Henighan, T., Chen, A., Thakur, D., Sooryakumar, R.* & Winter, J.O.* Simultaneous magnetic manipulation and fluorescent tracking of multiple individual hybrid nanoparticles. Nano Letters 10, 2220-2224 (2010)

4、Ruan, G., Agrawal, A., Marcus, A.I. & Nie S.* Imaging and tracking of Tat peptide-conjugated quantum dots in living cells: new insights into nanoparticle uptake, intracellular transport, and vesicle shedding. Journal of the American Chemical Society129, 14759-14766 (2007).

5、Ruan, G. & Feng, S.S.* Preparation and characterization of poly(lactic acid)-poly(ethylene glycol)-poly(lactic acid) (PLA-PEG-PLA) microspheres for controlled release of paclitaxel. Biomaterials 24, 5037-5044 (2003).

6、Ruan, G., Feng, S.S.* & Li, Q.T. Effects of material hydrophobicity on physical properties of polymeric microspheres formed by double emulsion process. Journal of Controlled Release84, 151-160 (2002). ^[1] 

1、Ruan, G. Methods of making nanoparticle composites. US Patent no. 14/538,516 (US and China patent pending)

2、Ruan, G., Mahajan, K. & Winter, J.O. A New method to fabricate PLGA nanoparticles with sub-100 nm size and narrow size distribution. Patent no. 61/433,794 (US patent pending)

3、Ruan, G. & Winter, J.O. Nanoparticles with continuously changing colors, and preparations thereof, and methods of use in tracking of single nanoparticles and molecules. Patent no. 61/251,841 (US patent pending)

4、Ruan, G. & Winter, J.O. Nanocontainers of block copolymer micelles to co-encapsulate multiple types of nanospecies, and formulations thereof, and methods of use. Patent no. 61/483,091 (US patent pending) ^[1]