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裴正康
鎖定
1976年裴正康獲得台灣大學醫學博士學位;1977年在美國 St. Jude兒童研究醫院從事兒童白血病的研究和治療;2014年,當選台灣中央研究院院士;2015年當選為中國工程院外籍院士。
[1-2]
- 中文名
- 裴正康
- 外文名
- ChingHon Pui
- 國 籍
- 美國 [8]
- 民 族
- 漢族
- 出生地
- 中國台灣
- 出生日期
- 1951年8月
- 畢業院校
- 台灣大學
- 職 業
- 教育科研工作者
- 主要成就
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2014年當選中國台灣中央研究院院士
2015年當選為中國工程院外籍院士
裴正康人物經歷
1951年8月,裴正康出生於中國台灣。
1977年,在美國 St. Jude兒童研究醫院從事兒童白血病的研究和治療。
裴正康主要成就
裴正康科研成就
- 科研綜述
裴正康教授應邀訪問院所並做專題學術報告(4張)
- 學術論著
Pui CH. To delay or not to delay, that is the question for patients with acute lymphoblastic leukemia who do not receive prophylactic cranial irradiation.CancerOct 10, 2018. doi: 10.1002/cncr.31756
Pui CH, Yang JJ, Bhakta N, Rodriguez-Galindo C. Global efforts toward the cure of childhood acute lymphoblastic leukaemia.Lancet Child Adolesc HealthJun;2(6):440-454, 2018. doi: 10.1016/S2352-4642(18)30066-X
Pui CH. Is testicular irradiation necessary for patients with acute lymphoblastic leukemia and testicular relapse?Pediatr Blood CancerMay;65(5):e26977, 2018. doi: 10.1002/pbc.26977
Pui CH,Liu Y, Relling MV. How to solve the problem of hypersensitivity to asparaginase?Pediatr Blood CancerMar;65(3), 2018. PMCID: PMC5766401
Pui CH,Campana D. Minimal residual disease in pediatric ALL.OncotargetSep 13;8(45):78251-78252, 2017. PMCID: PMC5667954
Pui CH,Roberts KG, Yang JJ, Mullighan CG. Philadelphia chromosome-like acute lymphoblastic leukemia.Clin Lymphoma Myeloma LeukAug;17(8):464-470, 2017. PMCID: PMC5638138
Pui CH,Pei D, Raimondi SC, Coustan-Smith E, Jeha S, Cheng C, Bowman WP, Sandlund JT, Ribeiro RC, Rubnitz JE, Inaba H, Gruber TA, Leung WH, Yang JJ, Downing JR, Evans WE, Relling MV, Campana D. Clinical impact of minimal residual disease in children with different subtypes of acute lymphoblastic leukemia treated with response-adapted therapy.LeukemiaFeb;31(2):333-339, 2017. PMCID: PMC5288281
Pui CH.Is Erwinase Necessary for all Children With ALL and Allergic Reactions to E. coli Asparaginase?Pediatr Blood CancerApr;63(4):587-588, 2016. PMCID: PMC4755852
Pui CH, Yang JJ, Hunger SP, Pieters R, Schrappe M, Biondi A, Vora A, Baruchel A, Silverman LB, Schmiegelow K, Escherich G, Horibe K, Benoit YC, Izraeli S, Yeoh AE, Liang DC, Downing JR, Evans WE, Relling MV, Mullighan CG. Childhood Acute Lymphoblastic Leukemia: progress through collaboration.J Clin Oncol33(27):2938-48, 2015.
Pui CH, Pei D, Coustan-Smith E, Jeha S, Cheng C, Bowman WP, Sandlund JT, Ribeiro RC, Rubnitz JE, Inaba H, Bhojwani D, Gruber TA, Leung WH, Downing JR, Evans WE, Relling MV, Campana D. Clinical utility of sequential minimal residual disease measurements in the context of risk-based therapy in childhood acute lymphoblastic leukaemia: a prospective study.Lancet Oncol16(4):465-474, 2015.
Zhang J, Walsh MF, Wu G, Edmonson MN, Gruber TA, Easton J, Hedges D, Ma X, Zhou X, Yergeau DA, Wilkinson MR, Vadodaria B, Chen X, McGee RB, Hines-Dowell S, Nuccio R, Quinn E, Shurtleff SA, Rusch M, Patel A, Becksfort JB, Wang S, Weaver MS, Ding L, Mardis ER, Wilson RK, Gajjar A, Ellison DW, Pappo AS,Pui CH, Nichols KE, Downing JR. Germline Mutations in Predisposition Genes in Pediatric Cancer.N Engl J Med373(24):2336-46, 2015.
Mullighan CG, Jeha S, Pei D, Payne-Turner D, Coustan-Smith E, Roberts KG, Waanders E, Choi JK, Ma X, Raimondi SC, Fan Y, Yang W, Song G, Yang JJ, Inaba H, Downing JR, Leung WH, Bowman WP, Relling MV, Evans WE, Zhang J, Campana D,Pui CH. Outcome of children with hypodiploid ALL treated with risk-directed therapy based on MRD levels.Blood2015 Nov 2. pii: blood-2015-09-671131.
Pui CH, Pei D, Campana D, Cheng C, Sandlund JT, Bowman WP, Hudson MM, Ribeiro RC, Raimondi SC, Jeha S, Howard SC, Bhojwani D, Inaba H, Rubnitz JE, Metzger ML, Gruber TA, Coustan-Smith E, Downing JR, Leung WH, Relling MV, Evans WE. A revised definition for cure of childhood acute lymphoblastic leukemia.Leukemia28(12):2336-43, 2014.
Roberts KG, Pei D, Campana D, Payne-Turner D, Li Y, Cheng C, Sandlund JT, Jeha S, Easton J, Becksfort J, Zhang J, Coustan-Smith E, Raimondi SC, Leung WH, Relling MV, Evans WE, Downing JR, Mullighan CG,Pui CH. Outcome of children with BCR-ABL1-like acute lymphoblastic leukemia treated with risk-directed therapy based on the levels of minimal residual disease.J Clin Oncol32(27):3012-20, 2014.
Yeoh AE, Tan D, Li CK, Hori H, Tse E,Pui CH. Management of adult and paediatric acute lymphoblastic leukaemia in Asia: resource-stratified guidelines from the Asia Oncology Summit 2013.Lancet Oncol14:e508-523, 2013.
Pui CH, Evans WE. A 50-year journey to cure childhood acute lymphoblastic leukemia.Semin Hematol50(3):185-96, 2013.
Krull KR, Bhojwani D, Conklin HM, Pei D, Cheng C, Reddick WE, Sandlund JT,Pui CH. Genetic mediators of neurocognitive outcomes in survivors of childhood acute lymphoblastic leukemia.J Clin Oncol31(17):2182-2188, 2013.
Bhojwani D,Pui CH. Relapsed childhood acute lymphoblastic leukaemia.Lancet Oncol14(6):e205-17, 2013.
Pui CH, Mullighan CG, Evans WE, Relling MV. Pediatric acute lymphoblastic leukemia: where are we going and how do we get there?BloodJune 22, 2012.
Downing JR, Wilson RK, Zhang J, Mardis ER,Pui CH, Ding L, Ley TJ, Evans WE. The pediatric cancer genome project.Nat Genet44(6):619-22, 2012.
Pui CH, Pei D, Pappo AS, Howard SC, Cheng C, Sandlund JT, Furman WL, Ribeiro RC, Spunt SL, Rubnitz JE, Jeha S, Hudson MM, Kun LE, Merchant TE, Kocak M, Broniscer A, Metzger ML, Downing JR, Leung W, Evans WE, Gajjar A. Treatment outcomes in black and white children with cancer: results from the SEER database andSt JudeChildren's Research Hospital, 1992 through 2007.J Clin OncolApril 30, 2012.
Leung W,Pui CH, Coustan-Smith E, Yang J, Pei D, Gan K, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Shook D, Rubnitz JE, Sandlund JT, Jeha S, Inaba H, Ribeiro RC, Handgretinger R, Laver JH, Campana D. Detectable minimal residual disease before hematopoietic cell transplantation is prognostic but does not preclude cure for children with very-high-risk leukemia.BloodApril 19, 2012.
Schrappe M, Hunger SP,Pui CH, Saha V, Gaynon PS, Baruchel A, Conter V, Otten J, Ohara A, Versluys AB, Escherich G, Heyman M, Silverman LB, Horibe K, Mann G, Camitta BM, Harbott J, Riehm H, Richards S, Devidas M, Zimmermann M. Outcomes after induction failure in childhood acute lymphoblastic leukemia.N Engl J Med366(15):1371-81, 2012.
Zhang J, Ding L, Holmfeldt L, Wu G, Heatley SL, Payne-Turner D, Easton J, Chen X, Wang J, Rusch M, Lu C, Chen SC, Wei L, Collins-Underwood JR, Ma J, Roberts KG, Pounds SB, Ulyanov A, Becksfort J, Gupta P, Huether R, Kriwacki RW, Parker M, McGoldrick DJ, Zhao D, Alford D, Espy S, Bobba KC, Song G, Pei D, Cheng C, Roberts S, Barbato MI, Campana D, Coustan-Smith E, Shurtleff SA, Raimondi SC, Kleppe M, Cools J, Shimano KA, Hermiston ML, Doulatov S, Eppert K, Laurenti E, Notta F, Dick JE, Basso G, Hunger SP, Loh ML, Devidas M, Wood B, Winter S, Dunsmore KP, Fulton RS, Fulton LL, Hong X, Harris CC, Dooling DJ, Ochoa K, Johnson KJ, Obenauer JC, Evans WE,Pui CH, Naeve CW, Ley TJ, Mardis ER, Wilson RK, Downing JR, Mullighan CG. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia.Nature481(7380):157-63, 2012.
Diouf B, Cheng Q, Krynetskaia NF, Yang W, Cheok M, Pei D, Fan Y, Cheng C, Krynetskiy EY, Geng H, Chen S, Thierfelder WE, Mullighan CG, Downing JR, Hsieh P,Pui CH, Relling MV, Evans WE. Somatic deletions of genes regulating MSH2 protein stability cause DNA mismatch repair deficiency and drug resistance in human leukemia cells.Nat Med17(10):1298-1303, 2011.
Leung W, Campana D, Yang J, Pei D, Coustan-Smith E, Gan K, Rubnitz JE, Sandlund JT, Ribeiro RC, Srinivasan A, Hartford C, Triplett BM, Dallas M, Pillai A, Handgretinger R, Laver JH,Pui CH. High success of hematopoietic cell transplantation regardless of donor source in children with very high-risk leukemia.BloodMay 25, 2011.
Howard SC, Jones DP,Pui CH. The tumor lysis syndrome.N Engl J Med364(19):1844-54, 2011.
Mullighan CG, Zhang J, Kasper LH, Lerach S, Payne-Turner D, Phillips LA, Heatley SL, Holmfeldt L, Collins-Underwood JR, Ma J, Buetow KH,Pui CH, Baker SD, Brindle PK, Downing JR. CREBBP mutations in relapsed acute lymphoblastic leukaemia.Nature471(7337):235-9, 2011.
Yang JJ, Cheng C, Devidas M, Cao X, Fan Y, Campana D, Yang W, Neale G, Cox NJ, Scheet P, Borowitz MJ, Winick NJ, Martin PL, Willman CL, Bowman WP, Camitta BM, Carroll A, Reaman GH, Carroll WL, Loh M, Hunger SP,Pui CH, Evans WE, Relling MV. Ancestry and pharmacogenomics of relapse in acute lymphoblastic leukemia.Nat GenetFebruary 6, 2011.
Pui CH, Carroll WL, Meshinchi S, Arceci RJ. Biology, risk stratification, and therapy of pediatric acute leukemias: an update.J Clin OncolJanuary 1, 2011.
裴正康人才培養
裴正康榮譽表彰
年份 | 榮譽/表彰 | 授予機構 |
---|---|---|
1996年 | 美國臨牀研究學會會員 | |
1998年 | 美國促進會會員 | |
1999年 | 美國醫師協會會員 | |
2007年 | 華人成就獎 | 孟菲斯華人聯合會 |
2009年 | AACR團隊科學獎(團隊領導) | |
2011年 | ASH Henry M.Stratton獎 | 美國癌症研究學會 |
2011年 | Joseph H.Bur chenal 臨牀研究獎 | |
2014年 | 台灣中央研究院院士 | 台灣中央研究院 |
2015年 | 中國工程院外籍院士 | 中國工程院 |
裴正康社會任職
裴正康人物評價
- 參考資料
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- 1. 裴正康 .中國工程院[引用日期2019-08-13]
- 2. 全球兒童白血病領軍人物裴正康院士擔任廣醫兒科學院、廣州市婦兒中心榮譽客座教授 .廣州市婦女兒童醫療中心.2017-11-01[引用日期2018-01-11]
- 3. 各級級社 .香港培正同學會[引用日期2019-08-16]
- 4. 美國聖潔德兒童研究醫院腫瘤科主任裴正康(Ching-Hon Pui)教授應邀訪問院所並做專題學術報告 .中國醫學科學院血液學研究所血液病醫院[引用日期2018-01-11]
- 5. 心懷堅持不讓任何孩子失去生命 .同濟大學關工委[引用日期2019-08-15]
- 6. Ching-Hon Pui, MD .St. Jude Children's Research Hospital[引用日期2019-08-16]
- 7. 上海兒童醫學中心血液腫瘤中心首席顧問裴正康教授榮獲2020年上海市“白玉蘭紀念獎” .澎湃新聞網[引用日期2018-01-11]
- 8. 院士館-中國工程院外籍院士--裴正康 .中國工程院[引用日期2023-04-09]