李文凱

主要從事醫學類（研究生、八年制、七年制、五年制各專業和國際留學生）生物化學理論與生化實驗教學及人類重要病原生物高特異性分子診斷與相關疾病的治療研究。

主編全國高等醫學院校規劃教材1部，參編全國高等醫藥院校生物化學教材和參考書十餘部（其中英文版教材2部）。參與省級、校級教改課題4項，主持校級教改課題1項，獲校級教學質量優秀獎2次，校級教學成果獎1次。參與國家、省自然科學基金項目7項，申請國家實用新型專利2項，授權1項，發表教學、科研論文四十餘篇。

1. Wenkai Li, Xinru Feng, Xing Yan, Keyi Liu, Le Deng. A DNA aptamer against influenza A virus: an effective inhibitor to the hemagglutinin-glycan interactions. Nucleic Acid Therapeutics, 2016,26(3):166-172

2. Xinghua Ding, Ruoxu Liu, Wenkai Li, Hengjia Ni, Yong Liu, Dandan Wu, Shuguang Yang, Jing Liu, Bo Xiao, Shaojun Liu. A metabonomic investigation on the biochemical perturbation in post-stroke patients with depressive disorder (PSD). Metab Brain Dis, 2016, 31(2): 279-287. DOI 10.1007/s11011-015-9748-z

3. Xing Yan, Wenkai Li, Keyi Liu and Le Deng. Highly sensitive fluorescent aptasensor for Salmonella paratyphi A via DNase I-mediated cyclic signal amplification. Anal.Methods, 2015, 7: 10243-10250

4. Yi Ning, WenKai Li, YingFen Duan, Ming Yang, Le Deng. High specific DNAzyme-aptamer sensor for Salmonella paratyphiA using single-walled nanotubes- based dual fluorescence-spectrophotometric methods. Journal of Biomolecular Screening. 2014; DOI: 10.1177/1087057114528538.

5. Yang Song, Wenkai Li, Yingfen Duan, Zhongjie Li, Le Deng, Nicking enzyme-assisted biosensor for Salmonella enteritidis detection based on fluorescence resonance energy transfer. Biosensors and Bioelectronics.2014 May; 55: 400-404.

6. Mao P, Ning Y, Li W, Peng Z, Chen Y, Deng L. Novel strategy combining SYBR Green I with carbon nanotubes for highly sensitive detection of Salmonella typhimurium DNA. Enzyme Microb Technol. 2014 Jan;54:15-19.

7. Zhou Q, Chen Y, Yang M, Li W, Deng L. Enhanced bioremediation of heavy metal from effluent by sulfate-reducing bacteria with copper-iron bimetallic particles support. Bioresour Technol. 2013 May;136:413-417.

8. Han-chun Chen, Wei-xin Hu, Qing-xia Liu, Wen-kai Li, Fang-zhi Chen, Zhou-zhou Rao, Xin-fa Liu, Ya-ping Luo and Yan-feiCao. Genetic polymorphisms of metabolic enzymes CYP1A1, CYP2D6, GSTM1 and GSTT1 and leukemia susceptibility. European Journal of Cancer Prevention 2008;17:251-258.

9. 李文凱,劉清霞,陳放知,駱亞萍,陳惠娟,夏嘉志,陳漢春.CYP1A1和CYP2D6基因多態性對白血病發生的影響.基礎醫學與臨牀.2008;28(6):553-556.

10. Yu Junlong, Wang Shiping, Li Wenkai, et al. Clonnig, expression and protective immunity evaluation of the full-length cDNA encoding succinate dehydrogenase iron-sulfur protein of Schistosomma japonucum. Sci China Ser C-Life Sci. 2007;50(2):221-227.

11. LI Wen-Kai, WANG Shi-ping, LÜ Zhi-Yue, PENG Xian-chu , XU Shao-rui , HE Zhuo , ZHOU Song-hua , XIAO Xiao-qin , ZENGShao-hua , DAI Gan , YU J un-long , CHE Hong-li. Anti-fecundity immunity induced by SIEA 26-28kDa antigens of Schistosoma japonicum：Is HGPRT a major target antigen for the immunity? Chinese Journal of Zoonoses.2005;21(1):1-4 . ^[1]