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李小波
(博士,西湖大學生命科學學院教師)
鎖定
李小波(1985-),江蘇宿遷人,現為西湖大學生命科學學院教師。
李小波博士長期從事植物學和微生物學研究。北京時間2023年10月6日,李小波團隊在Science發表題為“A chlorophyll c synthase widely co-opted by phytoplankton”的文章,首次揭示了葉綠素c合成酶編碼基因及該酶作用機制,挖掘了葉綠素c的生理功能,討論了該基因的演化形成與轉移。
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李小波個人簡介
2007年畢業於西安交通大學,獲得生物工程學士學位。
2007-2012年在密歇根州立大學攻讀植物學博士學位。
先後在斯坦福卡內基研究所(2012-2016)和普林斯頓大學(2016-2018)進行博士後研究。
2018年加入西湖大學任特聘研究員。
李小波代表論文
1.Li X, Patena W, Fauser F, Jinkerson RE, Saroussi S, Meyer MT, Ivanova N, Robertson JM, Yue R, Zhang R, Vilarrasa-Blasi J, Wittkopp TM, Ramundo S, Blum S, Goh A, Laudon M, Srikumar T, Lefebvre PA, Grossman AR, Jonikas MC. (2019) A genome-wide algal mutant library and functional screen identifies genes required for eukaryotic photosynthesis.Nature Genetics. DOI: 10.1038/s41588-019-0370-6.
· This manuscript presents the world’s first genome-wide, indexed and mapped mutant library for any unicellular photosynthetic organism; this research also reveals 303 candidate genes involved in photosynthesis (65 previously known and 238 novel)
2.Li X#, Handee W#, Kuo MH. (2017) The slim, the fat, and the obese: guess who lives the longest?Current Genetics. 63 (1): 43-49.
3.Li X#, Zhang R#, Patena W#, Gang SS, Blum SR, Ivanova N, Yue R, Robertson JM, Lefebvre PA, Fitz-Gibbon ST, Grossman AR, Jonikas MC. (2016) An indexed, mapped mutant library enables reverse genetics studies of biological processes in Chlamydomonas reinhardtii.The Plant Cell. 28 (2): 367-387.
·ESI highly cited paper(defined as top 1% in citation in the field of Plant & Animal Science for the publication year)
4. Handee W#,Li X#, Hall K, Li P, Benning C, Williams B, Kuo MH. (2016) An energy-independent pro-longevity function of triacylglycerol in yeast.PLOS Genetics. 12(2): e1005878.
· Reported by over 20 websites in China and USA
5.Li X, Jonikas MC. (2016) High-throughput genetics strategies for identifying new components of lipid metabolism in the alga Chlamydomonas reinhardtii.Lipids in plant and algae development. Yonghua Li-Beisson and Yuki Nakamura, eds (Springer Publishing), Series Subcellular Biochemistry, 86: 223-247.
6. Yang W#, Wittkopp T#,Li X, Warakanont J, Dubini A, Catalanotti C, Kim R, Mowack EMC, Mackinder L, Aksoy M, Page MD, D’Adamo S, Saroussi S, Heinnickel M, Johnson X, Richaud P, Alric J, Boehm M, Jonikas M, Benning C, Merchant S, Posewitz MC, Grossman AR. (2015) Critical role of Chlamydomonas reinhardtii ferredoxin-5 in maintaining membrane structure and dark metabolism.Proc Natl Acad Sci USA. 112(48): 14978-14983.
7. Kong F, Yamasaki T, Kurniasih SD,Li X, Ivanova N, Okada S, Ohama T. (2015) Robust expression of heterologous genes by selection marker fusion system in improved Chlamydomonas strains.Journal of Bioscience and Bioengineering. 120(3): 239-45.
8.Li X, Umen JG, Jonikas MC. (2014) Waking sleeping algal cells.Proc Natl Acad Sci USA. 111 (44): 15610-15611.
9.Li X, Moellering ER, Liu B, Johnny C, Fedewa M, Sears BB, Kuo MH, Benning C. (2012) A galactoglycerolipid lipase is required for triacylglycerol accumulation and survival following nitrogen deprivation in Chlamydomonas reinhardtii.The Plant Cell. 24(11): 4670-4686.
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李小波獲獎
獲得了美國遺傳學會的DeLill Nasser獎(2016)
國際植物脂類代謝論壇的 Paul Stumpf獎 (2016)
美國植物學家協會的Robert Rabson獎 (2016)。
- 參考資料
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- 1. 李小波博士 .西湖大學[引用日期2021-11-08]
- 2. 破解百年難題,西湖大學新發Science—新聞—科學網 .科學網.2023-10-06[引用日期2023-10-06]