張兆國

1968年11月出生於山東

1987-1991：山東大學化學系畢業，獲學士學位

1991-1994：南京大學化學系畢業，獲碩士學位 導師：徐建華教授

1994-1997：中國科學院上海有機化學研究所畢業，獲博士學位 導師：陸熙炎院士

1997-2000：賓西法尼亞州立大學化學系博士後 導師：張緒穆教授

2000，6- ：中國科學院上海有機化學研究所研究員

2000年度中國科學院百人計劃

2002年上海市科技啓明星

2004年中國科學院優秀研究生導師

2006年科技啓明星跟蹤

2007年曙光學者

2005-至今：上海交通大學化學與化工學院，教授 ^[1] 

2023年6月起任上海交通大學副校長。 ^[2] 

1、金屬有機化學與不對稱催化

2、精細有機合成

3、可見光條件下的催化反應 ^[1] 

主持和參加國家自然科學基金項目、中國科學院基金項目、國家重點實驗室開放基金項目和國際、國內企業合作項目。 ^[1] 

1、2000年獲中國科學院百人計劃

2、2002年獲上海市“科技啓明星”

3、2004年被評為中國科學院優秀研究生導師2

4、2006年獲得美國Eli Lilly Research Excellence Award

5、2007年獲上海市曙光學者 ^[1] 

美國化學會會員 ^[1] 

1、本科生：《有機合成》、

2、研究生：《高等有機合成》 ^[1] 

Zhu, L., Chen, H., Meng, Q., Fan, W., Xie, X., Zhang, Z., "Highly enantioselective hydrogenation of 2-oxo-4-arybutanoic acids to 2-hydroxy-4-arylbutanoic acids." Tetrahedron 2011, 67 (34), 6186-6190.

Yao, Y., Fan, W., Li, W., Ma, X., Zhu, L., Xie, X., Zhang, Z., "Synthesis of (S)-7-amino-5-azaspiro[2.4]heptane via highly enantioselective hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropanecarboxylates." J. Org. Chem. 2011, 76 (8), 2807-2813.

Yang, Y., Chen, L., Zhang, Z., Zhang, Y., "Palladium-catalyzed oxidative C-H bond and C=C double bond cleavage: C-3 acylation of indolizines with α,β-unsaturated carboxylic acids." Organic Letters 2011, 13 (6), 1342-1345.

Xie, X., Ni, G., Ma, F., Ding, L., Xu, S., Zhang, Z., "Palladium-catalyzed monoarylation of aryl amine with aryl tosylates." Synlett 2011, (7), 955-958.

Ma, F. F., Peng, Z. Y., Li, W. F., Xie, X. M.,Zhang, Z., "An efficient Pd-catalyzed coupling of hydrazine derivatives with aryl halides." Synlett 2011, (17), 2555-2558.

Ma, F., Xie, X., Ding, L., Gao, J., Zhang, Z., "Palladium-catalyzed coupling reaction of amino acids (esters) with aryl bromides and chlorides." Tetrahedron 2011, 67 (48), 9405-9410.

Li, X., Ma, X., Li, W., Tao, X., Meng, Q., Fan, W., Zhang, Z., "Catalytic asymmetric hydrogenation of ethyl 2-(benzo[b]thiophen-5-yl)-2- oxoacetate with ru-sunphos in the formal synthesis of T-588." Chinese Journal of Chemistry 2011, 29 (12), 2581-2583.

Li, W., Ma, X., Fan, W., Tao, X., Li, X., Xie, X., Zhang, Z., "Ru-catalyzed asymmetric hydrogenation of 3-oxoglutaric acid derivatives via solvent-assisted pinpoint recognition of carbonyls in close chemical propinquity." Organic Letters 2011, 13 (15), 3876-3879.

Fan, W., Li, W., Ma, X., Tao, X., Li, X., Yao, Y., Xie, X., Zhang, Z., "Ru-catalyzed asymmetric hydrogenation of γ-heteroatom substituted β-keto esters." J. Org. Chem. 2011, 76 (22), 9444-9451.

Zhu, L., Meng, Q., Fan, W., Xie, X., Zhang, Z., "Direct asymmetric hydrogenation of 2-oxo-4-arylbut-3-enoic acids." J. Org. Chem. 2010, 75 (17), 6027-6030.

Xie, X., Ding, L., Ni, G., Zhang, Z., Gao, J., "A general and facile approach for the synthesis of 2'-functionalized 1,1'-binapthyl-2-ols." Chinese Journal of Chemistry 2010, 28 (9), 1630-1634.

Wang, J., Tong, X., Xie, X., Zhang, Z., "Rhodium-catalyzed activation of C(sp3)-X (X = Cl, Br) bond: An intermolecular halogen exchange case." Organic Letters 2010, 12 (23), 5370-5373.

Peng, Z. Y., Ma, F. F., Zhu, L. F., Xie, X. M., Zhang, Z., "Lewis acid promoted carbon - Carbon double-bond formation via organozinc reagents and carbonyl compounds." J. Org. Chem. 2009, 74 (17), 6855-6858.

Lin, X., Busch-Petersen, J., Deng, J., Edwards, C., Zhang, Z., Kerns, J. K., "Efficient and scalable synthesis of 3,5,7-trisubstituted 1H-indazoles as potent IKK2 inhibitors." Synlett 2008, (20), 3216-3220.

Xie, X., Zhang, T. Y., Zhang, Z., "Synthesis of bulky and electron-rich MOP-type ligands and their applications in palladium-catalyzed C-N bond formation." J. Org. Chem. 2006, 71 (17), 6522-6529.

Zhu, L., Chen, H., Meng, Q., Fan, W., Xie, X., Zhang, Z., "Highly enantioselective hydrogenation of 2-oxo-4-arybutanoic acids to 2-hydroxy-4-arylbutanoic acids." Tetrahedron 2011, 67 (34), 6186-6190.

Yao, Y., Fan, W., Li, W., Ma, X., Zhu, L., Xie, X., Zhang, Z., "Synthesis of (S)-7-amino-5-azaspiro[2.4]heptane via highly enantioselective hydrogenation of protected ethyl 1-(2-aminoaceto)cyclopropanecarboxylates." J. Org. Chem. 2011, 76 (8), 2807-2813.

Xie, X., Zhang, T. Y., Zhang, Z., "Synthesis of bulky and electron-rich MOP-type ligands and their applications in palladium-catalyzed C-N bond formation." J. Org. Chem. 2006, 71 (17), 6522-6529.

Wang, D.; Zhang, Z. “Activation and reaction of carboxylic anhydride catalyzed by palladium ” Chin. J. Org. Chem.2004, 24, 258-269.

Guo, M.; Li, D.; Sun, Y.; Zhang, Z. “Selective Reduction of the Carbonyl Group in b,g-Unsaturated a-Ketoesters by Transfer Hydrogenation with Ru-TsDPEN” Synlett, 2004, 741-743

Luo, Y.; Wang, F.; Zhu, G.; Zhang, Z. “A concise synthesis of 2-diarylphosphino-20-methoxy-1,10-binaphthalenes (MOPs) by simple resolution”, Tetrahedron Asymm. 2004, 15, 15-17.

Guo, M.; Li, D.; Zhang, Z. “Novel Synthesis of 2-Oxo-3-butynoates by Copper-Catalyzed Cross-Coupling Reaction of Terminal Alkynes and Monooxalyl Chloride”, J. Org. Chem. 2003, 68, 10172-10175.

Wang, D.; Zhang, Z. “Palladium-Catalyzed Cross-Coupling Reactions of Carboxylic Anhydrides with Organozinc Reagents”, Org. Lett., 2003, 5, 4645-4648.

Zhu, G.; Zhang, Z. “Palladium-Catalyzed Tandem Cyclization/Suzuki Coupling of 1,6-Enynes”, Org. Lett., 2003, 5, 3645-3648.

Cheng, J.; Wang, F.; Xu, J.-H.; Pan, Y.; Zhang, Z. “Palladium-catalyzed Suzuki–Miyaura reaction using aminophosphine as ligand”, Tetrahedron Lett., 2003, 44, 7095-7098.

Tong, X., Zhang, Z., Zhang, X., “Novel Rhodium-Catalyzed Cycloisomerization of 1,6-Enynes with an Intramolecular Halogen Shift” J. Am. Chem. Soc. 2003, 125, 6370-6371.

Zhang, Z.; Lu, X*. and Lang, S. “An Unexpected Reaction of Allyl Propynoate under Palladium Catalysis” Chin. J. Chem. 2002, 20, 1287-1290.

Wang, F. and Zhang Z.* “Palladium Catalyzed Amidocarbonylation”, Chin. J. Org. Chem. 2002, 22, 536-542.

Tian, J. Z.; Zhang, Z. G.; Yang, X. L.; Fun, K. H. and Xu*, J. H “Photooxygenation of Indolizines via Selective Excitation of Their Charge Transfer Complexes with Molecular Oxygen” J. Org. Chem. 2001, 66, 8230-8235

Zhang,Z.; Lu, X.*; Xu, Z.; Zhang, Q. and Han, X. “Role of Halide Ions in Divalent Palladium-Mediated Reactions: Competition between ‚-Heteroatom Elimination and ‚-Hydride Elimination of a Carbon-Palladium Bond”, Organometallics 2001, 20, 3724-3728

Zhang, Z.; Qian, H.; Longmire, J. and Zhang, X*. “Synthesis of Chiral Bisphosphines with Tunable Bite Angles and Their Applications in Asymmetric Hydrogenation of –Ketoesters”, J. Org. Chem. 2000; 65; 6223-6226.

Li, W.; Zhang, Z.; Xiao, D. and Zhang, X*. “Synthesis of Chiral hydroxl Phosphines from D-Mannitol and Their Use in Asymmetric Catalytic Reactions” J. Org. Chem., 2000, 65, 3489-3496.

Wang, Z.; Zhang, Z.; Lu, X*. “Effect of Halide Ligands on the Reactivity of Carbon-Palladium Bonds: Implications for Designing Catalytic Reactions” Organometallics, 2000, 19, 775-780.

Li, W.; Zhang, Z.; Xiao, D.; Zhang, X*. “Rhodium-hydroxyl bisphospholane catalyzed highly enantioselective hydrogenation of dehydroamino acids and esters” Tetrahedron Lett., 1999, 40, 6701-6704.

Jiang, Q.; Xiao, D.; Zhang, Z.; Cao, P.; Zhang, X*. “Highly enantioselective hydrogenation of cyclic enol acetates catalyzed by a Rh-PennPhos complex” Angew. Chem., Int. Ed., 1999, 38, 516-518.

Zhang, Z.; Zhu, G.; Jiang, Q.; Xiao, D.; Zhang, X*. Highly Enantioselective Hydrogenation of Cyclic Enamides Catalyzed by a Rh-PennPhos Catalyst” J. Org. Chem., 1999, 64, 1774-1775.

Xiao, D.; Zhang, Z.; Zhang, X*. “Synthesis of a Novel Chiral Binaphthyl Phospholane and Its Application in the Highly Enantioselective Hydrogenation of Enamides” Org. Lett., 1999, 1, 1679-1681.

Xiao, D.; Zhang, Z.; Jiang, Q.; Zhang, X.. “Syntheses of novel chiral 2,5-dialkyl-7- azabicyclo[2.2.1]heptanes and 2,5-dialkyl-7-thiobicyclo[2.2.1]heptanes” Tetrahedron Lett., 1998, 39, 5331-5334.

Wang, Z.; Lu, X*.; Lei, A.; Zhang, Z. “Efficient Preparation of Functionalized (E,Z) Dienes Using Acetylene as the Building Block” J. Org. Chem., 1998, 63, 3806-3807.

Lu, X*.; Zhu, G.; Wang, Z.; Ma, S.; Ji, J.; Zhang, Z. “Enyne cyclization methodology for the synthesis of bioactive lactones” Pure Appl. Chem., 1997, 69, 553-558.

Lu, X.; Zhu, G.; Wang, Z.; Ma, S.; Ji, J.; Zhang, Z. “Enyne cyclization methodology for the synthesis of bioactive lactones” Youji Huaxue, 1997. 17, 8-11.

Zhang, Z.; Lu, X*. “Total synthesis of phaseolinic acid by enyne cyclization” Tetrahedron: Asymm. 1996, 7, 1923-1928.

Xu, J.; Song, Y.; Zhang, Z.; Wang, L.; Xu, J*. “Photoinduced addition reactions of chloranil with alkenes - factors influencing the reaction site” Tetrahedron, 1994, 50, 1199-1210.

Chen, C.; Zhang,Z.; Yan, B.; Xu, J*. “Phtoinduced Reactions of Chloranil with Aromatic Imines” Tetrahedron Lett. 1994, 35, 9221-9224.

Yan, B.; Zhang, Z.; Yuan, H.; Wang, L. and Xu, J*. “Photoinduced Electron- transfer Reactions of Chloranil with Benzodioxoles” J. Chem. Soc. Perk. T 2, 1994, 2545-2550. ^[1]