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周長林

（中國藥科大學教授）

鎖定
周長林，1964年1月生，1986、1989和1997年於華東理工大學生物工程專業分別獲學士、碩士和博士學位，1999~2000年日本近畿大學藥學部訪問學者，2004~2005年美國ProvidenceCollege生物系博士後。
現任中國藥科大學生命科學與技術學院微生物學教研室主任、教授，中國微生物學會江蘇省微生物學分會理事，中華醫學會江蘇省免疫學分會委員。 [1] 
中文名
周長林
國    籍
中國
出生日期
1964年
畢業院校
華東理工大學

目錄

  1. 1 人物經歷
  2. 2 研究方向
  3. 3 主要成就
  1. 4 獲獎記錄
  2. 5 社會任職
  3. 6 人物評價
  1. 7 發表論文專著

周長林人物經歷

2002年被授予江蘇省普通高等學校“青藍工程”優秀青年骨幹教師稱號。2008年獲得江蘇省“青藍工程”中青年學術帶頭人。

周長林研究方向

抗感染藥物藥效及機理、微生物代謝調控與藥物生物合成 [1] 

周長林主要成就

2008年被評為江蘇省“青藍工程”中青年學術帶頭人 [1] 

周長林獲獎記錄

江蘇省科學技術獎三等獎 [3] 

周長林社會任職

江蘇省生物工程學會副理事長，江蘇省第九屆生物化學和分子生物學學會常務理事 [1] 

周長林人物評價

無

周長林發表論文專著

（1）Zhou Wang, Lingman Ma, Mengqi Su, Yiran Zhou, Ke Mao, Chengqin Li, Guangyong Peng, Changlin Zhou*, Baiyong Shen* and Jie Dou*. Baicalin induces cellular senescence in human colon cancer cells via upregulation of DEPP and the activation of Ras/Raf/MEK/ERK signaling. Cell Death and Disease (2018) 9:217, DOI 10.1038/s41419-017-0223-0 (IF 5.965) [4] 
（2）Yu C, Wei S, Han X, Liu H, Wang M, Jiang M, Guo M, Dou J, Zhou C*, Ma L*. Effective inhibition of Cbf-14 against Cryptococcus neoformans infection in mice and its related anti-inflammatory activity. Fungal Genet Biol. 2018 Jan;110:38-47. doi: 10.1016/j.fgb.2017.11.008. Epub 2017 Dec 6 (IF 3.072)
（3）Jing Jin, Shuo chen Dechuan Wang, Yuanjin Chen, Yuxu Wang, Ming Guo, Changlin Zhou*, Jie Dou*. Oroxylin A suppresses influenza A virus repplication correlating with neuraminidase inhibition and induction of IFNs. Biomedicine & Pharmacotherapy. (2017), 97:385-394
（4）Wei Kang1, Hanhan Liu1, Lingman Ma, Mengxiao Wang, Shanshan Wei, Pengbo Sun, Meiling Jiang, Min Guo, Changlin Zhou*, Jou Dou*. Effective antimicrobial activity of a peptide mutant Cbf-14-2 against penicillin-resistant bacteria based on its unnatural amino acids. European Journal of Pharmaceutical Science. (2017), 105:169-177 (IF 3.756)
（5）Xin Xie, Yiran Zhou, Xue Wang, Jian Guo, Jingwen Li, Hongye Fan, Jie Dou, Baiyong Shenb*, Changlin Zhou*. Enhanced antitumor activity of gemcitabine bypolysaccharide-induced NK cell activation and immune cytotoxicityreduction in vitro/vivo. Carbohydrate Polymers, 173 (2017) 360–371 (IF 4.811)
（6）Wei Kang, Hanhan Liu, Lingman Ma, Mengxiao Wang, Shanshan Wei , Pengbo Sun, Meiling Jiang, Min Guo, Changlin Zhou*, Jie Dou*. Effective antimicrobial activity of a peptide mutant Cbf-14-2 against penicillin-resistant bacteria based on its unnatural amino acids. European Journal of Pharmaceutical Sciences, European Journal of Pharmaceutical Sciences, 105 (2017) 169–177 (IF 3.773)
（7）LI Jing-Wen△, LIU Yang△, LI Bao-Hui, Wang Yue-Yang, WANG Hui, ZHOU Chang-Lin*. A polysaccharide component purified from Radix Adenophorae promotes cell activation and pro-inflammatory cytokine production of murine RAW264.7 macrophages. Chinese Journal of Natural Medicines. 2016, 14(5): 0370-0376 (IF 1.382)
（8）Mengyun Ke, Hui Wang, Yiran Zhou, Jingwen Li, Yang Liu, Min Zhang, Jie Dou, Tao Xi, Baiyong Shen*, Changlin Zhou*. SEP enhanced the antitumor activity of 5-fluorouracil by up-regulating NKG2D/MICA and reversed immune suppression via inhibiting ROS and caspase-3 in mice. Oncotarget(2016), DOI: 10.18632/oncotarget.10375 (IF 5.008)
（9）Hailong Chen, Zhilai Wang, Haibo Cai, Changlin Zhou*. Progress in the Microbial Production of S-Adenosyl-L-methionine. World J Microbiol Biotechnol (2016), 32(9), 1-8 (IF 1.532)
（10）Bo Li, Wei Kang,Hanhan Liu, Yanrong Wang, Changzhong Yu, Xinyi Zhu, Jie Dou, Haibo Cai, Changlin Zhou*. The antimicrobial activity of Cbf-K16 against MRSA was enhanced by β-lactam antibiotics through cell wall non-integrity. Archives of Pharmacal Research (2016), DOI 10.1007/s12272-016-0769-x (IF 2.490)
（11）Lingman Ma, Yanrong Wang, Mengxiao Wang, Yuwei Tian, Wei Kang, Hanhan Liu, Hui Wang, Jie Dou*, Changlin Zhou*. Effective antimicrobial activity of Cbf-14, derived from a cathelin-like domain, against penicillin-resistant bacteria. Biomaterials (2016). 87: 32-45 (IF 8.387)
（12）Jie Yu, Dechuan Wang, Jing Jin, Jun Xu, Mengwei Li, Hui Wang, Jie Dou, Changlin Zhou*, Antiviral activity of SA-2 against influenza A virus in vitro/vivo and its inhibition of RNA polymerase. Antiviral Research. (2016), 127: 68-78 (IF 4.909)
（13）Hailong Chen, Jie Dou, Yang Yang, Baohui Li, Changlin Zhou*. Elevated intracellular acetyl-CoA availability by acs2 overexpression and mls1 deletion combined with metK1 introduction enhanced SAM accumulation in Saccharomyces cerevisiae. Biochemical Engineering Journal (2016), 107: 26-34. (IF 2.463)
（14）Hailong Chen, Zhou Wang, Zhilai Wang, Jie Dou, Changlin Zhou*. Improving methionine and ATP availability by MET6 and SAM2 co-expression combined with sodium citrate feeding enhanced SAM accumulation in Saccharomyces cerevisiae. World J Microbiol Biotechnol (2016), 32:56 (IF 1.532)
（15）Yang Yang, Chao Yuan, Jie Dou, Xiaorong Han, Hui Wang, Hongqing Fang, Changlin Zhou*. Recombinant expression of glpK and glpD genes improves the accumulation of shikimic acid in E. coli grown on glycerol. World J Microbiol Biotechnol (2014), 30: 3263-3272 (IF 1.779)
（16）Yue Ding, Jie Dou, Zaijin Teng, Jie Yu, Tingting Wang, Na Lu, Hui Wang, Changlin Zhou*. Antiviral activity of baicalin against influenza A (H1N1/ H3N2) virus in cell culture and in mice and its inhibition of neuraminidase. Arch Virol (2014), 159 (12): 3269-3278 (IF 2.39)
（17）Wang Y, Wang W, Lv Y, Zheng W, Mi Z, Pei G, An X, Xu X, Han C, Liu J, Zhou C*, Tong Y*. Characterization and complete genome sequence analysis of novel bacteriophage IME-EFm1 infecting Enterococcus faecium.J Gen Virol. 2014 Nov; 95(Pt 11): 2565-75 (IF 3.183)
（18）Mengyun Ke, Hui Wang, Min Zhang, Yuwei Tian, Yizhou Wang, Bing Li, Jie Yu, Jie Dou, Tao Xi, Changlin Zhou*. The anti-lung cancer activity of SEP is mediated by the activation and cytotoxicity of NK cells via TLR2/4 in vivo. Biochemical Pharmacology, 2014, 89: 119-130 (IF 5.009)
（19）Jing Wang, Bing Li, Yang Li, Jie Dou, Qingru Hao, Yuwei Tian, Hui Wang, Changlin Zhou*. BF-30 effectively inhibits ciprofloxacin-resistant bacteria in vitro and in a rat model of vaginosis. Arch Pharm Res. 2014, 37(7): 927-936 (IF 2.046) [1-2] 
參考資料