周江寧

周江寧 ^[2]  ，男, 1956年10月4日出生於江蘇省南京市。現任中國科技大學生命科學院神經生物學與生物物理學系主任、神經生物學教授，博士生導師。中國神經科學學會常務理事、中國神經科學學會神經發育專業委員會主任委員。中國藥理學會抗衰老和痴呆專業委員會副主任委員。

1985年寧夏醫學院碩士畢業，1996年荷蘭AMSTERDAM 大學醫學系博士畢業。1996年至1998年荷蘭皇家科學院腦研究所博士後。1998年回國在安徽醫科大學第一附屬醫院工作，曾任老年醫學教授，副主任醫師，副院長，安徽省老年病研究所所長，中科院知識創新工程重要方向項目首席科學家，中國科學神經科學會理事。2001年入選中國科學院“百人計劃”。2002年建立了國內第一家“中國人腦庫”。現為國家973項目中期評估組專家成員。承擔了國家重點基礎研究發展規劃項目（973）、國家高新技術領域規劃項目（863）、國家國際合作重點項目、國家自然科學基金委項目等國家級項目九項，獲資助經費近800萬元。 ^[1] 

主要從事神經精神系統疾病的發病機制與診治基礎的研究。在以“Nature”為代表的SCI期刊發表論文40篇。Nature 論文被評為1995年世界100項重大科學發現之一。

2000年獲安徽省科技進步（自然科學類）一等獎。

2002年國際“性別鑑定研究和教育學會”研究論文獎；

國家“百千萬”工程第一、第二層次人選；

國家級有突出貢獻的中青年專家，教育部骨幹教師，享受國務院政府特殊津貼。 ^[1-2] 

近五年承擔國家科技計劃項目情況： ^[2] 

Zhou J-N., Hofman M. A., Gooren L. J. G and Swaab D. F. A sex difference in the human brain and its relation to transsexuality . Nature. Vol.378,68-70 (1995).

Zhou J-N., Hofman M. A. and Swaab D. F.VIP neurons in the human SCN in relation to sex ,age and Alzheimer’s disease. Neurobiology of Aging. Vol.16,571-576(1995).

Zhou J-N., Hofman M. A. and Swaab D. F. No changes in the number of vasoactive intestinal polypeptide(VIP)-expressing neurons in the suprachiasmatic nucleus of homosexual men; comparison with vasopressin-expressing neurons. Brain Research. Vol.672,285-288(1995).

Zhou J-N., Swaab D. F. Age-related changes in neuropeptidergic neurons in the human hypothalamus. in Molecular Basis of Aging. ed by Macieira-Coelho A.CRC press,Boca Raton, pp. 527-552(1995).

Zhou J-N., Hofman M. A. and Swaab D. F. Morphometric analysis of vasopressin and vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus, influence of microwave treatment. Brain Research. 742,334-338(1996).

Zhou J-N., Hofman M. A. and Swaab D. F. Alteration in the human hypothalamus start in middle age but are more severe in Alzheimer's Disease. Neurobiology of Aging. 19, S309(1998).

Zhou J-N. and Swaab D. F. Activation and degeneration during aging, A morphometric study of the human hypothalamus. In Histology of the hypothalamic-pituitary axis. Microscopy Research and Techniques. 44, 36-48(1999).

Zhou J-N., Hu X-Y., Liu R-Y., Qin S. Ostrogen receptor containing neurons decrease in the hippocampus of Alzheimer patients. Neurobiology Aging. 21, s264(2000).

Zhou J-N., Riemersma R. F, Witte Hoogendijk. J. G., Swaab D. F. Alterations in Arginine Vasopressin Neurons in the Suprachiasmatic Nucleus in Depression. Arch Gen Psychlatry. VOL.58,July 2001;58,655-662(2001).

Zhou J-N., Liu R-Y., Van Heerikhuize J., Hofman M. A. and Swaab D. F. Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J. Pineal Res. 34,11-16(2003).

周江寧 (2001) 衰老和老年性痴呆中晝夜節律調節系統的改變, 復旦神經生物學講座, NO.255。

周江寧，劉榮玉.。 (2000) 老年性痴呆的非藥物治療 老年性痴呆的治療和護理（盛樹立主編）, pp. 158-175， 科學技術文獻出版社。

周江寧 （2002）雌激素與Alzheimer Disease.。神經科學進展（科學出版社）pp,315-318。

周江寧 （2001）前額葉皮質與下丘腦在抑鬱症發病中的作用。安徽醫科大學學報。Vol.36 No.4,247-250。

Liu R-Y, Zhou J-N., Hoogendijk W. J. G., Van Heerikhuize J., Kamphorst W, Unmehopa U. A., Hofman M. A., and Swaab D. F. Decreased vasopressin mRNA expression in the suprachiasmatic nucleus in Alzheimer's disease. J. Neuropath Exp Neurol. 59（4）,314-322(2000).

Liu R-Y., Zhou J-N. Alteration of vasopressin mRNA expression in the suprachiasmatic nucleus of the patients with Alzheimer’s disease. Neurobiology Aging. 21, s54(2000).

Liu R-Y, Zhou J-N, Van Heerikhuize J, Hofman M. A and Swaab D. F. Decreased melationin levels in postmortem cerebrospinal fluid in elation to aging, Alzheimer’s disease and ApoE-ε4/4 genotype. J. Clin Endocr&Metab. 84,323-327(1999).

Liu R-Y, Zhou J-N, Kamphorst W, Hofman M.A, Swaab D.F The first appearance of neurofibrillary tangles and plaques in the temporal cortex of aged controls is accompanied by decreased cerebrospinal fluid melatonin levels. Neurobiology of aging. Vol.23, Iss1, pp,1397- (2002)

Liu R-Y, Zhou J-N (2001). Biological Rhytm disorder, In aging and Alzheimer’s disease. Neuroendocrinologie des demences. Pp,11-30..

劉榮玉, 周江寧。糖皮質激素對人視交叉上核加壓素表達的影響。中國藥理學通報。16（3）,286-289 (2000)。

劉榮玉, 周江寧。腦脊液松果體素晝夜和季節節律在衰老和老年痴呆中的改變。 中華老年醫學雜誌。19（4）,258-261(2000)。

劉榮玉, 周江寧。人視交叉上核加壓素基因表達的晝夜節律改變。安徽醫科大學學報35（2）,88-90(2000)。

Swaab D. F., Zhou J-N., Ehlhart T. and Hofman M. A. Development of vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus in relation to birth and sex. Development of Brain Research. Vol.79,249-259(1994).

Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Gender and sexual orientation-related differences in the human hypothalamus. in Sex differentiation clinical and biological aspect(ed.Hughes). Frontiers in Endocrinology 20, Cambridge, 135-152(1996).

Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human hypothalamus, differences according to sex, sexual orientation, and transsexuality in Sexual Orientation Toward Biological Understanding. (ed by Ellis L., Praeger, Westport) pp.129-150(1997).

Swaab D. F., Zhou J-N., Fodor M. and Hofman M. A. Sexual differentiation of the human brain. Biomedical Reviews. 7, 17-32(1997).

Swaab D. F., Hofman M. A., Van Smeren E. J. W. and Zhou J-N. (1993). Development and aging of the biological clock. In De Biologische klok praktische toepassingen in klinjek en huisartspraktijk. (ed. Rietved W. J and Kerkhof G. A Leiden 1993) pp. 9-23.

Swaab D. F., Hofman M.A., Mirmiran M., Van Someren E. J. W., and Zhou J-N. The human suprachiasmatic mucleus (SCN) in a periodic environment. New functional aspect of the suprachiasmatic nucleus. pp. 232-336(1994).

Swaab D. F., Slob A. K., Houtsmuller E. J., Brand T. and Zhou J-N. Increased number of vasopressin neurons in the suprachiasmatic nucleus (SCN) of ‘bisexual’ adult male rats fllowing perinatal treatment with the aromataes blocker ATD. Dev. Brain Research. Vol.85,273-279(1995).

Swaab D.F, Fliers E, Hoogendijk W.J.G, Veltman D.J, Zhou J-N. Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression. Progress in brain research.Vol.126, pp,369-396(2001)

Swaab D.F., VanSomeren E.J.W., Zhou J-N, Hofman M.A. (1996) Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus. Hypothalamic integration of circadian rhythms. Vol.111, pp,349-368.

Hofman M.A., Zhou J-N, Swaab D.F. No evidence for a diurnal vasoactive intestinal polypeptide(VIP) rhythm in human suprachiasmatic nucleus. Brain Research. Vol.722,78-82(1996).

Hofman M.A., Zhou J-N, Swaab D.F. Suprachiasmatic nucleus of the human brain, An immunocytochemical and morphometric analysis. Anatomical Record. Vol.244,552-562(1996).

Hoogendijk W. J. G., Van Someren, E. J. W., Mirmiran M., Hofman M. A., Lucassen P. L., Zhou J-N and Swaab D. F. Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer’s disease. International Psychogeriatrics. Vol.8,245-252 (1996).

Kruijver F. P. M., Zhou J-N, Pool C. W., Hofman M. A., Gooren L. J. G., Swaab D. F. Male-to-female transsexuals have female neuron numbers in a limbic neurocleus. J Clin Endocr&Metab. 85,2034-2041 (2000).

Wang Q-S, Zhou J-N, Xu T-L, Li L-S A phospholipase C inhibitor, phenylmethylsulfonyl fluoride, ameliorates ischemic injury to brain mitochondria in rats. Acta Pharmacol Sin, Mar, 22（3）,249-252 (2001).

Wang Q-S, Zhou J-N. Retrieval and encoding of epsodic memory in normal aging and patients with mild cognitive inpairment. Brain Research. 924,113-115(2002).

Wang Q-S, Tian L, Huang Y-L, Qin S, He L-Q, Zhou J-N. Olfactory identification and apolipoprotein Eε4 allele in mild cognitive impairment. Brain Research. 951,77-81(2002).

Wang Q-S, Qin S, Zhou J-N. Olfactory identification and apolipoprotein E epsilon-4 allele in mild cognitive impairment. Neurobiology of aging. Vol.23, Iss1, pp,635- (2002)

汪青松，許浩，秦松，趙卉，吳穎慧，黃永璐，周江寧。輕度認知損害患者情節記憶的編碼和提取。中國神經科學雜誌。Vol.18 No.1,451-463（2002）。

Hu X-Y, Zhang H-Y, Qin S, Xu H, Swaab D. F., Zhou J-N. (Increased p75NTR expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Neurobiology of aging. Vol,23, Iss1, pp,997-.2002).

Hu X-Y, Zhou J-N, Swaab D.F Decreeased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphorylated tau in Alzheimer patients. Neurobiology of aging. Vol.23, Iss1, pp,1808- (2002).

Huang Y-L, Liu R-Y, Wang Q-S, Van Someren E.J.W., Xu H, Zhou J-N. Age-associated difference in circadian sleep-wake and rest-activity rhythms. Physiology&Behavior. 76, 597-603(2002).

黃永璐，汪青松，吳穎慧，周江寧。晝夜靜息-活動、睡眠-覺醒節律的年齡相關性變化。安徽醫科大學學報。Vol.37 No.1,44-46（2002）。

Xu H, Hu X-Y, Wu L, Zhou J-N.(2002) Neurotensin expressing neurons developed earlier than vasoactive intestinal polypeptide and vasopressin expressing neurons in the human suprachiasmatic nucleus. Neuroscience Letters.

許浩，胡祥友，秦松，周江寧。阿爾茨海默病腦海馬凋亡神經元發生率增高。中國神經科學雜誌。Vol.18 No.1,462-465（2002）.

Wang K, Hoosain R, Li X-S, Zhou J-N, Wang C-Q, Fu X-M, Yue X-M. Impaired recognition of fear in a Chinese man with bilateral cingulated and unilateral amygdala damage. Cognitive neuropsychology. Vol.19,pp,641-652(2002).

Bao A-M, Zhou J-N, Liu R-Y, Wang Y-L, Cao Y-X, Chu X-H Circadian rhythm of free estrogen during menstrual cycle and its periodic regression analysis. Neurobiology of aging. Vol.23, Iss 1, pp,640-(2002)

陳貴海，周江寧。神經遞質認識過程的哲學思考。醫學與哲學。Vol.23 No.3,9-11（2002）。 ^[2]