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張偉濱

鎖定
張偉濱,男,漢族,1964年6月生,研究生,博士,主任醫師。
現任第十四屆全國政協委員,民進中央委員 [6]  ,民進上海市委副主委,上海市政協常委、教科文衞體委員會副主任,上海交通大學醫學院附屬瑞金醫院骨科主任、上海市傷骨科研究所副所長。 [1]  [5] 
中文名
張偉濱
國    籍
中國
民    族
漢族
出生日期
1964年6月
臨牀職稱
主任醫師
執業地點
上海交通大學醫學院附屬瑞金醫院
政治面貌
民進會員 [1]  [5-6] 

張偉濱人物經歷

2022年7月18日,中國民主促進會上海市第十三次代表大會,民進上海市第十七屆委員會第一次全體會議選舉張偉濱為民進上海市第十七屆委員會副主委。 [2]  [5] 
第十四屆全國政協委員 [9]  ,中國人民政治協商會議上海市第十四屆委員會委員、常委 [7-8] 

張偉濱研究方向

低氧誘導因子介導的髓核細胞退變機理研究
骨肉瘤肺轉移作用機理及免疫治療靶點譜篩選的影響 [4] 

張偉濱學術任職

中華醫學會骨質疏鬆與骨礦鹽疾病委員會委員
上海肉瘤專業委員會副主任委員
中國抗癌協會肉瘤專業委員會常務委員
中國醫師協會骨科醫師分會常務委員
上海骨科專科委員會副主任委員
上海骨科醫師協會副會長
中華醫學會腫瘤學會骨與軟組織腫瘤學組委員
中華醫學會骨科學分會基礎學組副組長
中華醫學會骨科學會骨腫瘤學組委員
上海市骨質疏鬆專科委員會副主任委員
中華醫學會骨科學分會委員 [4] 

張偉濱擅長領域

各種骨腫瘤保肢治療,轉移性骨腫瘤的綜合治療,骨質疏鬆診治 [3] 

張偉濱負責項目

項目編號
項目名稱
課題來源
起止年月
批准經費
14JC1492400
表面特殊微納米羥基磷灰石生物學作用機理研究
上海市科委重點科技攻關納米項目
2014-09~2017-08
40萬元
81172550
阻斷 PI3K/mTOR 信號通路誘導分化並靶向治療骨肉瘤幹細胞的分子機制研究
國家自然科學基金
2012-01~2015-12
55萬元
10431901202
重組人MNV-骨形態發生蛋白-2的II期臨牀研究生物學檢測
上海市科委科技支撐計劃生化重點科技攻關專項
2010-09~2013-09
34萬元
08411950600
股骨粗隆間骨質疏鬆性骨折的生物力學評估評價及指導個體最優化內固定應用
上海市科委生化重點科技攻關項目
2008-09~2011-09
25萬元

張偉濱代表論文

作者
論文標題
期刊名
出版年
卷期頁碼
Liu Zhuochao, Wen Junxiang, Wu Chuanlong, Hu Chuanzhen, Wang Jun, Bao Qiyuan, Wang Hongyi, Wang Jizhuang, Zhou Qi, Wei Li, Shen Yuhui, Zhang Weibin (通訊作者)
MicroRNA-200a induces immunosuppression by promoting PTEN-mediated PD-L1 upregulation in osteosarcoma
Aging
2020
12(2), 1213-1236
Zang S, He Q, Bao Q, Shen Y, Zhang W (通訊作者)
Establishment and validation of a novel survival prediction scoring algorithm for patients with non-small-cell lung cancer spinal metastasis.
Int J Clin Oncol
2019
24(9):1049-1060
Fangzhou He,Le Qin, Qiyuan Bao, Shizhao Zang,Qin He,Shijing Qiu, Yuhui Shen, Weibin Zhang (通訊作者)
Pre-Operative Chemotherapy Response Assessed by contrast-enhanced MRI Can Predict the Prognosis of Enneking surgical margins in Patients with Osteosarcoma.
J Orthop Res
2019
37(1) : 258-264
Jizhuang Wang; Chuanzhen Hu; Jun Wang; Yuhui Shen; Qiyuan Bao; Fangzhou He; Hongyi Wang; Liangzhi Gong; Zhuochao Liu; Fangqiong Hu; Jing Liang; Qi Zhou; Li Wei; Junxiang Wen; Weibin Zhang
Checkpoint Blockade in Combination With Doxorubicin Augments Tumor Cell Apoptosis in Osteosarcoma. 18.
J Immunother
2019
42(9):321-330
Pei Yu, Junxiang Wen, Jun Wang, Jing Liang, Yuhui Shen, Weibin Zhang (通訊作者)
Establishment and characterization of a novel human osteosarcoma cell line for spontaneous pulmonary metastasis research in vivo
Ann Transl Med
2019
7(20):573-580
Zhuochao Liu, Zhiyong Zheng, Jin Qi, Jun Wang, Qi Zhou, Fangqiong Hu, Jing Liang,Changwei Li , Weibin Zhang (通訊作者),Xingkai Zhang
CD24 identifies nucleus pulposus progenitors/notochordal cells for disc regeneration.
Journal of Biological Engineering
2018
(12):35-50
Liangzhi Gong, Qiyuan Bao, Chuanzhen Hu, Jun Wang, Qi Zhou , Li Wei, Lei Tong, Weibin Zhang (通訊作者), Yuhui Shen
Exosomal miR-675 from metastatic osteosarcoma promotes cell migration and invasion by targeting CALN1.
Biochemical and Biophysical Research Communications
2018
(500):170-176
Fangzhou He, Chuanzhen Hua, Yuhui Shena, Qiyuan Bao, Junxiang Wen, Shijing Qiu,Rong Wan, Weibin Zhang (通訊作者)
Patellar height influences knee function in patients withaggressive bone tumors of the proximal tibia after endoprosthetic reconstruction.
Knee
2018
(25): 952–958
Qiyuan Bao, Yuhui Shen, Weibin Zhang. (通訊作者)
Metastatic Biopsy of Osteosarcoma with Circulating RNA
Ann Surg Oncol
2018
25(Suppl 3):936-937
Qiyuan Bao, , Liangzhi Gong, Jizhuang Wang, Junxiang Wen, Yuhui Shen (通訊作者), Weibin Zhang
Extracellular Vesicle RNA Sequencing Reveals Dramatic Transcriptomic Alterations Between Metastatic and Primary Osteosarcoma in a Liquid Biopsy Approach
Ann Surg Oncol
2018
(25) :2642–2651
C. Hu, J. Wen, L. Gong, X. Chen, Y. Shen, W. Zhang (通訊作者), J. Wang, F. Hu, Q. Zhou, J. Liang, L. Wei
Thrombospondin-1 promotes cell migration, invasion and lung metastasis of osteosarcoma through FAK dependent pathway
Oncotarget
2017
8(44): 75881-75892
C. Hu, X. Chen, J.X. Wen, L.Z. Gong, Z.C.Liu,J. Wang, J. Liang, F.Q. Hu, Q. Zhou, L. Wei, Y.H. Shen, W. Zhang. (通訊作者)
Antitumor effect of focal adhesion kinase inhibitor PF562271 against human osteosarcoma in vitro and in vivo
Cancer Sci
2017
108 :1347–1356
Zhuochao Liu, Changwei Li, Xiangchao Meng, Yunting Bai, Jin Qi,Jun Wang, Qi Zhou, Weibin Zhang (通訊作者), Xingkai Zhang.
Hypoxia-inducible factor-la mediates aggrecan and collagen P expression via NOTCH1 signaling in nucleus pulposus cells during intervertebral disc degeneration.
Biochem Biophys Res Commun
2017
488: 554-561
Fangzhou He,Weibin Zhang (通訊作者),Yuhui Shen, Pei Yu, Qiyuan Bao, Junxiang Wen, Chuanzhen Hu, Shijing Qiu
Effects of resection margins on local recurrence of osteosarcoma in extremity and pelvis: Systematic review and meta-analysis
Int J Surg
2016
36 : 283-292
Gong Liangzhi, Zhang Weibin (共同第一作者),Shen Yuhui
Magnesium substituted hydroxyapatite whiskers: synthesis, characterization and bioactivity evaluation
RSC Adv
2016
6, 114707–114713
Xu Chen, Chuanzhen Hu, Weibin Zang (通訊作者), Yuhui Shen, Jun Wang, Fangqiong Hu, Pei Yu
Metformin inhibites the proliferation , metastasis, and cancer stem-like sphere formation in osteosarcoma MG63 cell in vitro
Tumor Biology
2015
2015 Jul 13
Wu Zhang, Meng-LeiDing, Jia-Nian Zhang, Jian-ru Qiu, Yu-Hui Shen, Xiao-Yi Ding, Lian-fu Deng, Wei-Bin Zhang, Jian Zhu (通訊作者)
mTORC1 Maintains Tumoriginity of SSEA4 + High- Grade Osteosarcoma
Scientfic Reports
2015
1-13
Y. SUNNASSEE, R. WAN, Y. SHEN, J. XU, E. P. SOUTHERN,W. ZHANG (通訊作者)
Preliminary results for the use of knee mega-endoprosthesis in the treatment of musculoskeletal complications of haemophilia
Haemophilia
2014
():1-8
Jianqiang Xu, Yaoqi Yang, Rong Wan, Yuhui Shen, Weibin Zhang (通訊作者)
Hydrothermal Preparation and Characterization of tralong Strontium-Substituted ydroxyapatite Whiskers Using Acetamide as Homogeneous Precipitation Reagent
The Scientific World Journal
2014
():1-6
LIU Pei-yi, ZHANG Wei-bin,WEI Yi-yong (通訊作者)
Targeting the mammalian target of rapamycin pathway in osteosarcoma using combinative chemotherapy
Chin Med J
2013
126(10):197-8
劉沛宜、張偉濱、王君、沈宇輝、魏義勇。,2013;35(3):175-180 (通訊作者)
雷帕黴素對骨肉瘤幹細胞和人骨肉瘤細胞中雷帕黴素靶蛋白傳導通路的抑制作用及意義
中華腫瘤雜誌
2013
35(3):175-180
Yuhui Shen, Jinhao Liu, Kaili Lin, Weibin Zhang (通訊作者)
48) Yuhui Shen, Jinhao Liu, Kaili Lin, Weibin Zhang. Synthesis of strontium substituted hydroxyapatite whiskers used as bioactive and mechanical reinforcement material
Materials Letters
2012
70():76-79
袁高翔、王蕾、張偉濱、沈宇輝、陳博
動力髖螺釘與股骨近端防旋髓內釘治療骨質疏鬆性股骨轉子間骨折的有限元比較研究
中華創傷骨科雜誌
2012
14(10):876-882
Gao-Xiang Yuan, Yu-Hui Shen, Bo Chen, Wei-Bin Zhang. (通訊作者)
Biomechanical comparison of internal fixations in osteoporotic intertrochanteric fracture. A finite element analysis
J Saudi medica
2012
7():732-739
Weibin Zhang, Waiching Liu, Weiming Gu,Lei Chen, Yuhui Shen
Strontium modification of biomaterial: the effective approach to enhance the bioactivity and biocompatibility of calcium silicate
Advanced Materials Research
2012
391():195-199
Wan R, Zhang W (通訊作者), Xu J, Hao P, Yang Y, Shen Y, Ding X, Qiu S
The outcome of surgical treatment for recurrent giant cell tumor in the appendicular skeleton. J Orthop Sci
J Orthop Sci
2012
17():464-469
陳要林、林開澤、張偉濱(通訊)、王青禾、張武、沈宇輝、方成
人骨肉瘤細胞致瘤性與臨牀預後關係的實驗研究
上海醫學
2012
35(2):145-148
Zhang W, Li G, Deng R, Deng L, Qiu S
New bone formation in a true bone ceramic scaffold loaded with desferrioxamine in the treatment of segmental bone defect: a preliminary study
J Orthop Sci
2012
17():289-298
王俊青,郝平,萬榮,顏凌,張偉濱 (通訊作者)
三維重建MRI術前評價骨肉瘤IOR/OS-N4新輔助化療療效的臨牀應用
診斷學理論與實踐
2012
11(3):283-289
Zhang W, Pan W, Zhang M, Wei Y
In vivo evaluation of two types of bioactive scaffold used for tendon-bone interface healing in the reconstruction of anterior cruciate ligamen
Biotechnol Lett
2011
33():837-844
Weibin Zhang, Yuhui Shen, Haobo Pan
Effects of strontium in modified biomaterials.
Acta Biomaterialia
2011
7():800-808
Zhang W, Shen Y, Wan R, Zhu Y
Primary clear cell sarcoma of the sacrum: a case report
Skeletal Radiol
2011
40():633-639
張偉濱 (共同第一作者),沈宇輝,萬榮,周琦,朱亞萍,齊進.
骨折斷端血管性血友病因子表達在骨折癒合中的生物學意義
中華創傷雜誌
2008
-
代洪賓,杜寧,林開澤,蔣水明,張偉濱. (通訊作者)
雄激素對雄性去勢大鼠微結構及力學性能的影響
中國骨傷
2008
-
袁石福,張偉濱 (通訊作者),沈宇輝,朱雅萍,王琚魏立
成骨細胞與骨髓間充質幹細胞DNA甲基化差異的實驗研究
上海醫學
2008
-
張偉濱 (共同第一作者),王蕾,沈宇輝,王亞梓,徐建強
鎖定鋼板治療橈骨遠端不穩定性骨質疏鬆性骨折
中華創傷雜誌
2008
-
代洪賓,李飛躍,羅仕華,張風華,張偉濱. (通訊作者)
健骨湯對去睾丸大鼠松質骨的影響
中國中醫骨傷科雜誌
2008
-
代洪賓,李飛躍,符詩聰,林開澤,蔣水明,張偉濱. (通訊作者)
雄激素對男性骨質疏鬆大鼠模型骨的影響
中國骨質疏鬆雜誌
2008
-
張偉濱 (共同第一作者),莊澄宇,李建民,楊志平,陳曉亮.
鹽酸氨基葡萄糖治療骨性關節炎有效性與安全性評價
中華外科雜誌
2007
-

張偉濱出診時間

週二上午、四上午(特) [3] 
參考資料